ABSTRACT
Coagulation factor VII (FVII) deficiency is a congenital disorder with heterogeneous clinical phenotypes ranging from asymptomatic to life-threatening bleeding and/or thrombotic events. We present the case of an adolescent male who developed acute deep and superficial venous thromboses of the upper extremities in the setting of multiple peripheral venous line insertions and shortly after receiving his second coronavirus disease of 2019 immunization dose. A hemostatic work-up revealed low FVII activity levels associated with 4 different FVII genetic variants. We highlight the need to better understand the pathophysiologic mechanisms behind FVII deficiency-associated prothrombotic risk and the role that specific FVII genetic variants may play in the clinical presentation of these patients.
Subject(s)
Coronavirus Infections , Coronavirus , Factor VII Deficiency , Thrombosis , Male , Humans , Factor VII Deficiency/complications , Factor VII Deficiency/genetics , Factor VII/genetics , ImmunizationABSTRACT
The purpose of this literature review is to describe the state of the science on teen dating violence (TDV) research identifying support and barriers in accessing services. This review will help identify gaps in dating violence (DV) research and inform secondary and tertiary prevention services, as well as ways that these could be integrated into comprehensive primary prevention efforts. This review was conducted via electronic search through CINAHL, PubMed, and PsychINFO. Results show a serious lack of research in the content area and the importance of increasing research efforts in discovering supports for accessing DV services is emphasized.
