ABSTRACT
The authors present information on 44 patients with local breast carcinoma (Stages II and III) who were treated by a new type of operation in the form of radical subtotal resection of the breast and one-stage reconstruction without the use of endoprostheses. The authors describe some scientific and technical problems of the performance of these complicated surgical interventions. In future these operations may become operations of choice for a certain category of patients because they solve both therapeutic and rehabilitation problems.
Subject(s)
Breast Neoplasms/surgery , Mastectomy, Modified Radical , Breast Neoplasms/radiotherapy , Combined Modality Therapy , Female , Follow-Up Studies , Humans , Preoperative Care , Radiotherapy Dosage , Time FactorsABSTRACT
Combined treatment was used in 380 patients with breast cancer stage IIB, IIIA and IIIB. Preoperative therapy included large-fraction radiation (213 patients) or CMP chemotherapy course (176 patients). It was followed by radical mastectomy and postoperative chemotherapy, radiation. Cytograms of the specimens from the removed tumors were compared to pretreatment findings. This served the basis for recognition of 4 degrees of breast cancer pathomorphosis. The scheme can be used as additional morphological information on the degree of the breast cancer destruction and should be taken into consideration together with other data.