ABSTRACT
The incidence of the Helicobacter-like organisms (HLO) was investigated on biopsy specimens of antral gastric mucosa, stained by the Wayson technique, in 509 patients with various gastric and duodenal diseases. The incidence of HLO was: 72.8 percent in gastric ulcer, 69.6 percent in duodenal ulcer, 69.2 percent in bulbitis, 61.0. percent in chronic gastritis, 37.5 percent in the postoperative stomach, 50 percent in gastric cancer, and 34.3 percent on healthy controls. The HLO were present over the whole year, with a peak in March. Sex and age had little influence on the HLO incidence. The Wayson staining technique proved to be a good technique of detection of HLO on gastric mucosa smears.
Subject(s)
Campylobacter/isolation & purification , Duodenal Diseases/microbiology , Stomach Diseases/microbiology , Adult , Biopsy , Chronic Disease , Duodenal Ulcer/microbiology , Duodenitis/microbiology , Female , Gastric Mucosa/microbiology , Gastritis/microbiology , Humans , Male , Middle Aged , Postoperative Complications , Stomach Diseases/surgery , Stomach Neoplasms/microbiology , Stomach Ulcer/microbiologyABSTRACT
The present paper analyses, in correlation with histologic lesions, the incidence of infection with Campylobacter pylori (CP) in patients with chronic gastritis, operated stomach, gastric neoplasm and healthy subjects. In chronic gastritis, incidence of infection with CP is 71.6%, significantly increased in comparison with the controls, in whom the positive percentage is 37.5. The most of the patients in this group suffered from superficial chronic gastritis. In the group with operated stomach, the CP infection included 48% of the patients studied; all had superficial chronic gastritis. In gastric cancer, CP bacteria appeared in 50% of cases. CP may represent a pathogenetic ring that starts the gastric process.
Subject(s)
Campylobacter Infections/complications , Gastritis, Atrophic/etiology , Gastritis/etiology , Stomach Neoplasms/etiology , Biopsy , Campylobacter/isolation & purification , Campylobacter Infections/microbiology , Campylobacter Infections/pathology , Female , Gastritis, Atrophic/microbiology , Gastritis, Atrophic/pathology , Gastroscopy , Humans , Male , Middle Aged , Stomach/microbiology , Stomach/pathology , Stomach/surgery , Stomach Neoplasms/microbiology , Stomach Neoplasms/pathologyABSTRACT
The incidence of infection with Campylobacter pylori (CP) in gastric ulcer (GU) and duodenal ulcer (DU) and its correlation with the gastritis lesions associated to the two diseases, was investigated. In GU the incidence of CP infection was 76.3%, close to that in DU (71.4), but different from controls (33.3%). Chronic gastritis associated to gastric or duodenal ulcer is of variable severity, CP infection being the more often encountered the higher the severity of gastritis. Presence of CP was also observed in 75% of the cases associated also with intestinal metaplasia from UG. The diameter of CP-positive GU was significantly increased as compared with that in CP-negative GU. Type I GU was associated with CP infection in 81.8% of the cases. The results obtained allowed the conclusion that in GU and DU the incidence of CP infection is significantly higher as compared with that in controls but the pathogenetic relationship ulcer-bacterium is not yet elucidated.
