Subject(s)
Angiogenesis Inhibitors , Central Serous Chorioretinopathy , Intravitreal Injections , Propranolol , Rifampin , Vascular Endothelial Growth Factor A , Humans , Administration, Oral , Rifampin/administration & dosage , Rifampin/therapeutic use , Central Serous Chorioretinopathy/drug therapy , Central Serous Chorioretinopathy/diagnosis , Vascular Endothelial Growth Factor A/antagonists & inhibitors , Propranolol/administration & dosage , Angiogenesis Inhibitors/administration & dosage , Adrenergic beta-Antagonists/administration & dosageABSTRACT
We present a very rare case of torpedo maculopathy (TM) with multifocal central serous chorioretinopathy. A 26-year-old male presented with painless loss of vision in the right eye of 2 months duration. Clinical examination showed a torpedo-shaped lesion temporal to fovea and subretinal fluid in foveal center. Fluorescein angiography showed multifocal leaks. Optical coherence tomography showed an optically clear space/neurosensory detachment at the site of lesion. Patient underwent focal laser to the leaks. TM is a rare congenital disorder detected accidentally during routine fundus examination. It is usually unilateral and does not affect vision.
Subject(s)
Central Serous Chorioretinopathy/complications , Choroid/blood supply , Ciliary Arteries/diagnostic imaging , Macula Lutea/pathology , Visual Acuity , Adult , Central Serous Chorioretinopathy/diagnosis , Central Serous Chorioretinopathy/physiopathology , Computed Tomography Angiography , Fluorescein Angiography , Fundus Oculi , Humans , Male , Retinal Diseases/complications , Retinal Diseases/diagnosis , Retinal Pigment EpitheliumSubject(s)
Central Serous Chorioretinopathy/diagnosis , Choroid/pathology , Choroiditis/diagnosis , Fluorescein Angiography/methods , Fovea Centralis/pathology , Visual Acuity/physiology , Adult , Central Serous Chorioretinopathy/physiopathology , Central Serous Chorioretinopathy/surgery , Diagnosis, Differential , Fundus Oculi , Humans , Laser Therapy/methods , MaleABSTRACT
A 49-year-old man with lepromatous leprosy treated with dapsone monotherapy for 12 years (1967 to 1979) reported in the hospital in 2003, with relapsed disease. A slit skin smear showed a bacteriological index of 4+. Biopsies from skin lesions before and after anti-leprosy therapy showed features of lepromatous leprosy. Both biopsies showed unusual features of bacillary clumps in epidermal cells demonstrating clearly that dissemination of M. leprae can take place even through unbroken skin. The presence of lepra bacilli in clumps in the epidermis is an indicator that the skin is a potential route of transmission of the disease.