ABSTRACT
This is an analytic-descriptive study, parallel with a randomized, controlled trial performed at Amir'Alam Hospital, a tertiary referral center, with the aim of evaluating the correlation between otoacoustic emission (OAE) and auditory brainstem response (ABR) findings with hearing outcome after treatment of idiopathic sudden sensorineural hearing loss (SSNHL). Sixty patients with idiopathic SSNHL who presented to the emergency services and otology clinics between 2012 and 2014, and whose symptoms had begun <10 days previously, enrolled in this study. Before commencing treatment, distortion-product OAE (DP-OAE) and ABR were performed for all patients. They also underwent magnetic resonance imaging ± gadolinium. Therapeutic intervention was done in a parallel randomized, controlled trial, and responders to the medical therapy were selected for our final analysis. There was no significant correlation between the OAE record and responsiveness to treatment, but there was a correlation between ABR presence and the probability of responsiveness in patients with profound hearing loss who responded to medical therapy and had at least wave V ABR. However, in those who had no recorded wave, the response to treatment was variable. In conclusion, in patients with profound hearing loss, studying the waves of ABR could be a factor in predicting hearing loss resolution after treatment.
Subject(s)
Anti-Inflammatory Agents/administration & dosage , Evoked Potentials, Auditory, Brain Stem/drug effects , Hearing Loss, Sensorineural/physiopathology , Hearing Loss, Sudden/physiopathology , Otoacoustic Emissions, Spontaneous/drug effects , Adult , Aged , Aged, 80 and over , Audiometry, Evoked Response , Dexamethasone/administration & dosage , Female , Hearing Loss, Sensorineural/drug therapy , Hearing Loss, Sudden/drug therapy , Humans , Injection, Intratympanic , Male , Methylprednisolone/administration & dosage , Middle Aged , Treatment Outcome , Young AdultABSTRACT
OBJECTIVE: To determine functional results after lateral semicircular canal fenestration on congenital conductive hearing loss. STUDY DESIGN: Case series with chart review. SETTING: Amir-Alam otolaryngology tertiary referral center. SUBJECTS AND METHODS: Twenty patients with congenital oval window malformations who were not candidates for ossicular reconstruction underwent lateral semicircular canal fenestration. A skin graft was placed over the perforated fascial graft on the fenestrated area. RESULTS: The median preoperative mean air conduction (MAC) was 56.9 dB (50.0 dB median air-bone). Postoperative median MAC gain of 34.3 dB (P < 0.001) and the median air-bone gap of 18.8 dB were observed. The mean bone conduction (MBC) did not show any significant changes postoperatively (P = 0.12). No sensorineural hearing loss, tinnitus, or imbalance was observed. CONCLUSION: We demonstrated hearing improvement after lateral semicircular canal fenestration. This technique can be considered as an alternative for patients with middle ear anomalies who are not candidates for ossicular reconstruction.
