ABSTRACT
The ascorbic acid contents of skin, plasma and urine were estimated in 12 vitiligo cases, one albino and 10 normal subjects. All the estimations were repeated after saturation with ascorbic acid. There was no difference between the two groups with regard to the ascorbic acid contents of their plasma or urine. The ascorbic acid level of vitiliginous skin was decreased; however, this difference just falls short of significance at the level P = 0-05. Further investigations with a larger group of patients are indicated.
Subject(s)
Ascorbic Acid/analysis , Vitiligo/metabolism , Albinism/metabolism , Ascorbic Acid/blood , Ascorbic Acid/metabolism , Ascorbic Acid/urine , Female , Humans , Male , Melanins/biosynthesis , Pigmentation Disorders/metabolism , Skin/analysisABSTRACT
Malignant melanoma is rather uncommon in India. Pigmented moles are also less common than among Caucasians. The fewer number of moles probably is one factor responsible for the relative rarity of malignant melanomas in this area.
Subject(s)
Melanoma/epidemiology , Nevus, Pigmented/epidemiology , Skin Neoplasms/epidemiology , Adolescent , Adult , Child , Child, Preschool , Female , Humans , India , Infant , Male , Middle Aged , SunlightABSTRACT
Isopathic phenomenon of SAGHER was elicited in 21 proved leprosy patients (consisting of 7 lepromatous, 7 tuberculoid, 3 neuritic, 2 borderline, and 2 indeterminate types). The substances used to elicit the isopathic phenomenon were BCG lepromin, Indian ink and staphylococcal vaccine. Isopathic phenomenon was elicited in most of the cases and BCG was the substance which produced the most responses. The phenomenon could be used to classify difficult cases of leprosy.
