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8.
Bone Joint J ; 97-B(6): 862-8, 2015 Jun.
Article in English | MEDLINE | ID: mdl-26033070

ABSTRACT

Rebound growth after hemiepiphysiodesis may be a normal event, but little is known about its causes, incidence or factors related to its intensity. The aim of this study was to evaluate rebound growth under controlled experimental conditions. A total of 22 six-week-old rabbits underwent a medial proximal tibial hemiepiphysiodesis using a two-hole plate and screws. Temporal growth plate arrest was maintained for three weeks, and animals were killed at intervals ranging between three days and three weeks after removal of the device. The radiological angulation of the proximal tibia was studied at weekly intervals during and after hemiepiphysiodesis. A histological study of the retrieved proximal physis of the tibia was performed. The mean angulation achieved at three weeks was 34.7° (standard deviation (sd) 3.4), and this remained unchanged for the study period of up to two weeks. By three weeks after removal of the implant the mean angulation had dropped to 28.2° (sd 1.8) (p < 0.001). Histologically, widening of the medial side was noted during the first two weeks. By three weeks this widening had substantially disappeared and the normal columnar structure was virtually re-established. In our rabbit model, rebound was an event of variable incidence and intensity and, when present, did not appear immediately after restoration of growth, but took some time to appear.


Subject(s)
Bone Development/physiology , Epiphyses/surgery , Growth Plate/surgery , Tibia/surgery , Animals , Epiphyses/physiology , Epiphyses/physiopathology , Female , Growth Plate/physiology , Models, Animal , Orthopedic Procedures/instrumentation , Osteotomy/methods , Postoperative Period , Prospective Studies , Rabbits , Radiography , Tibia/diagnostic imaging , Tibia/pathology
9.
An. med. interna (Madr., 1983) ; 22(9): 441-444, sept. 2005. ilus, tab
Article in Es | IBECS | ID: ibc-042375

ABSTRACT

El síndrome de Schönlein-Henoch es una vasculítis sistémica que afecta a arteriolas y capilares. Aunque es un enfermedad típica de la infancia puede aparecer en edades más tardías. La enfermedad parece ser más severa en los adultos que la desarrollan. Las manifestaciones clínicas incluyen la clásica tétrada de rash cutáneo, artralgias, dolor abdominal y enfermedad renal, pero pueden verse afectados otros órganos como el miocardio, el pulmón, el uréter o el sistema nervioso central. La hemorragia pulmonar es una complicación rara del síndrome de Shönlein-Henoch, que aparece generalmente en adolescentes y adultos, y está asociada con una mortalidad significativa. Presentamos a un paciente de 76 años de edad con afectación renal severa, diagnosticado por biopsia renal de síndrome de Schönlein-Henoch, que desarrolla hemorragia pulmonar tras un tratamiento inicial con bolus de esteroides por glomerulonefrítis, desapareciendo la afectación pulmonar tras un segundo ciclo de bolus de esteroides


Schönlein-Henoch purpura is a systemic vasculitic disorder involving both arterioles and capillaries. Although it is mainly a disease of early chilhood, it can occur at any age. The disease may be more severe in the few adults who develop this disorder. The clinical manifestations include a classic tetrad: rash, arthralgias, abdominal pain and renal disease. However it may affect almost every other bodily organ such us myocardium, lungs, ureter and nervous system. Pulmonary hemorrhage, a rare complication of Schönlein-Henoch purpura, has been found mainly in adolescents and adults, and it is associated with significant mortality. We present a case of 76-year-old men with Schönlein-Henoch purpura, pulmonary haemorrhage and severe renal involvement. Therapy with intravenous prednisolone resulted in resolution of the pulmonary lesions and renal failure


Subject(s)
Male , Aged , Humans , Hemorrhage/etiology , Kidney Diseases/etiology , IgA Vasculitis/complications , Lung Diseases/etiology , Syndrome
10.
An Med Interna ; 22(9): 441-4, 2005 Sep.
Article in Spanish | MEDLINE | ID: mdl-16386079

ABSTRACT

Schönlein-Henoch purpura is a systemic vasculitic disorder involving both arterioles and capillaries. Although it is mainly a disease of early chilhood, it can occur at any age. The disease may be more severe in the few adults who develop this disorder. The clinical manifestations include a classic tetrad: rash, arthralgias, abdominal pain and renal disease. However it may affect almost every other bodily organ such us myocardium, lungs, ureter and nervous system. Pulmonary hemorrhage, a rare complication of Schönlein-Henoch purpura, has been found mainly in adolescents and adults, and it is associated with significant mortality. We present a case of 76-year-old men with Schönlein-Henoch purpura, pulmonary haemorrhage and severe renal involvement. Therapy with intravenous prednisolone resulted in resolution of the pulmonary lesions and renal failure.


Subject(s)
Hemorrhage/etiology , IgA Vasculitis/complications , Kidney Diseases/etiology , Lung Diseases/etiology , Aged , Humans , Male , Syndrome
13.
An Otorrinolaringol Ibero Am ; 22(4): 405-12, 1995.
Article in Spanish | MEDLINE | ID: mdl-7573859

ABSTRACT

We report a case of maxillary sitting of a calcifying odontogenic epithelial tumor (Pindborg's tumor). It is a benign tumor with similar microscopical findings with the ameloblastoma although its natural evolution is different. The tumor has an actodermal odontogenic origin. The stem cell from which it develops and its growth stimulus are unknown. Although the intermediary stratum of the enamel producing organ has been incriminated. A swelling of the maxillae or a casual finding--as the case reported--are the most common manifestations at beginning of these cases. The differential diagnosis depends on the radiological pattern we may find. Various surgical procedures may be considered optional. It could vary from enucleation to complete resection of the affected structure. Aggressive surgery is not indicated.


Subject(s)
Ameloblastoma/pathology , Calcinosis/pathology , Maxilla/pathology , Maxillary Neoplasms/pathology , Adolescent , Ameloblastoma/diagnosis , Ameloblastoma/surgery , Calcinosis/surgery , Diagnosis, Differential , Female , Humans , Maxilla/surgery , Maxillary Neoplasms/surgery
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