Short communication: Activity of nisin, lipid bilayer fragments and cationic nisin-lipid nanoparticles against multidrug-resistant Staphylococcus spp. isolated from bovine mastitis.

Staphylococci are the main etiological agents of bovine mastitis. Bacteriocins and nanoparticles have emerged as promising alternatives for the future development of antimicrobial agents. This study evaluated the activity of the bacteriocin nisin and bicelles of the synthetic cationic lipid dioctadecyldimethylammonium bromide, alone and in combination, against multidrug-resistant Staphylococcus spp. strains isolated from bovine mastitis. In summary, cationic nisin/dioctadecyldimethylammonium bromide nanoparticles are shown to be a promising alternative for the control of mastitis caused by multidrug-resistant Staphylococcus spp.

[Capsule endoscopy: indication, diagnosis and patient management in the doctor's office]. / Ambulante Dünndarmdiagnostik. Was leistet die Kapselendoskopie in der Praxis?

In this prospective clinical study, 50 consecutive patients in whom there was an indication for capsule endoscopy were evaluated with regard to indication, examination course, outcome and modifications to patient management, and the data obtained analysed. In 88% of the patients, capsule endoscopy revealed pathological changes. Patient management was modified in 78% of the cases.