ABSTRACT
Mirabilis Jalapa Linn. is a widely used traditional medicine in many parts of the world for the treatment of various diseases viz. virus inhibitory activity, anti tumour activity. It is claimed in traditional medicine that the leaves of the plant are used in the treatment of inflammation. In the present study, the total alcoholic extract and successive petroleum ether fractions of leaves of Mirabilis Jalapa Linn were screened for its anti-inflammatory activity using carageenan induced rat paw edema and cotton pellet induced granuloma models. The total alcoholic extract at the dose of 300 mg/kg p.o and successive petroleum ether fraction at the dose of 200 mg/kg exhibited significant anti-inflammatory activity in carrageenan induced paw edema model (p<0.01). In cotton pellet granuloma model, the total alcoholic extract at the dose of 300 mg/kg and successive petroleum ether fraction at the dose of 200 mg/kg inhibited granuloma formation significantly (p<0.05) indicating that both test samples inhibit the increase in number of fibroblasts and synthesis of collagen and mucopolysaccharides during granuloma tissue formation during the chronic inflammation. These experimental results have established a pharmacological evidence for the folklore claim of the drug to be used as an anti inflammatory agent.
ABSTRACT
Pandanus odoratissimus Linn.f. (Syn: Pandanus fascicularis Lamk) belongs to the family Pandanacea, is a palm like small tree or shrub, which usually grow in old world tropics and few warm temperate regions. Mostly all parts are medicinally used. In the present study, histological, physical, powdered characteristics and preliminary phytochemical investigations were carried out on the leaves of Pandanus odoratissimus Linn.f.
ABSTRACT
The present study deals with the macroscpical, microscopical and preliminary phytochemical investigation on Monochoria vaginalis P. The transverse section shows in the root, the presence of cork, cortex, xylem, phloem, pith etc. The diagnostic features of the roots are the presence of fibers associated with vessels, calcium oxalates, and xylem vessel which will help in the identification and authentification process of the drug. Preliminary phytochemical work of the alcoholic extract showed the presence of glycosides, flavonoids and tannins.