ABSTRACT
A complex simultaneous assessment of the microbiota (the aerobic and anaerobic links as well as the parietal and lumen components) of the gutter, vagina, and intestines of women with a pathological pregnancy was performed. In 30% of women the study revealed system dysbiotic changes. Local immune reactivity was decreased, which may be considered a provoking factor. In conclusion, complex microbiological examination makes it possible to objectivize the picture of the pathological process and its outcome. A criterion for the administration of correcting measures is offered.
Subject(s)
Abortion, Threatened/microbiology , Abortion, Threatened/pathology , Bacteria/isolation & purification , Intestines/microbiology , Oropharynx/microbiology , Pregnancy Trimester, First , Vagina/microbiology , Biopsy , Colony Count, Microbial , Female , Humans , Intestines/pathology , Oropharynx/pathology , Pregnancy , Risk Factors , Vagina/pathologyABSTRACT
Ligenten gel is a combined dosage form containing gentamicin (a broad spectrum antibiotic), lidocaine (an anesthetic) and ethonium (an antiseptic). The hydrogel sodium carboxymethylcellulose in combination with polyvinylpyrrolidone is used as the ligenten base. The clinical trials in urologic and gynecologic patients showed that ligenten had a high therapeutic efficacy in the treatment of inflammatory diseases, as well as an anesthetic action in instrumental examinations and surgical endoscopic manipulations.