[Predominantly intraductal low-grade differentiated adenocarcinoma in young man with long time mask clinic of chronic pancreatitis].

The authors present the case of diagnosis of low-grade adenocarcinoma of the pancreas, a man 34 years old, a long time to mask clinic chronic pancreatitis. Laboratory and instrumental investigations, including tumor markers CD 19-9, CEA, ultrasound, CT, MRI showed no reliable data for the presence of tumor. On the other hand, a young man of 34 years present credible evidence of chronic pancreatitis, in the form of a typical pain, a significant increase in serum am- ylase and lipase, and the presence of parenchymal and ductal signs of pancreatitis in visual research methods. Diagnosis of tumors, including obtaining morphological material, pre-operative pain relief were obtain by endoscopic methods. Histological examination of surgical specimens was detected a rare type of poorly differentiated adenocarcinoma of the pancreas tubulo-papillary structures, with predominant intraductal growth and a minimum depth of invasion due to pronounced fibrotic outcome variables, which leads to a complex disease diagnostics. After 1.5 years, after adequately performed surgery the patient was revealed metastases to the liver.

[Use of the multislice spiral computed tomography in planning the treatment of patients with tumors of the biliopancreatoduodenal zone].

The authors elucidate an experience with using multislice spiral computed tomography with the method of multiphase scanning (CT-angiography) in patients with suspected tumors of organs of the biliopancreatoduodenal zone. The proposed method allows getting information on the character of the pathological process, dissemination of the tumor lesion. It helps to decide on the strategy of treatment of the patient, to plan the operative intervention and assess the results of operative treatment.

[Morphological characteristic of labyrinthine zone of rat allantoic placenta after exposure to vibration of industrial frequency].

The labyrinthine zone of allantoic placenta was studied after dosated exposure to vibration. The study was carried out in pregnant female Wistar rats (n=68). Rats were subjected to short-term vibration from Day 9 to Day 13 and long-term vibration from the Day 9 to Day 18 of pregnancy (taking into account embryogenesis periodization and the development period of extraembryonic organs). Vibration table with fixed parameters (frequency of 32 Hz and acceleration of 50 m/s2) was used. Placental and fetal mass were measured, labyrinthine zone components were evaluated using the morphometric methods, while labyrinthine cord and fetal vessels along Duval's sinus were studied ultrastructurally. Labyrinth was analyzed from the point of view of rapprochement of maternal and fetal bloodstreams. It was found that the exposure to vibration together with the development of compensatory adaptive mechanisms led to chronic placental insufficiency. Experimental group with short-term vibration exposure (Days 9-13) is of particular interest since chronic placental insufficiency in this group should be considered as decompensated.

[Clinicophysiological assessment of physical performance in patients recovering from hemorrhagic fever with renal syndrome]. / Kliniko-fiziologicheskaia otsenka fizicheskoi trudosposobnosti u perenesshikh gemorragicheskuiu likhoradku s pochechnym sindromom.

Tolerance of physical load was investigated in 50 convalescents of hemorrhagic fever with renal syndrome (HFRS) at bicycle exercise test (BET). Calculations were made of maximal oxygen consumption and energy consumption at the threshold load. It is shown that for three months after HFRS physical performance of the convalescents remained low. By the end of the expected disability objective recovery of physical performance was registered only in 33-37% convalescents. More than for 3 months disability persisted in reconvalescents engaged in professions with energy consumption above 4.1 kkal/min throughout the working day. Use of BET in the practice of medical labour expertise of HFRS convalescents provides an objective assessment of their working ability and feasible job.

[Effects of hyperbaric oxygenation on free radical oxidation and antioxidant system of blood in the newborn who had acute hypoxia at birth]. / Vliianie giperbaricheskoi oksigenatsii na svobodnoradikal'noe okislenie i antioksidantnuiu sistemu krovi novorozhdennykh detei, perenesshikh ostruiu gipoksiiu pri rozhdenii.

Hyperbaric oxygenation (HBO) was added to the complex of intensive care for 14 full-term newborns born asphyxiated and with cerebral circulation disorders of the I-II degree. Study of the antioxidant enzymatic system and free-radical oxidation by chemiluminescence showed no changes in superoxide dismutase and catalase and a 1.6-2 times increase in the activity of glutathione peroxidase, on the one hand, and an appreciable decrease of free radical processes, on the other. This permitted a conclusion about the absence of toxic effects during HBO and on its membrane-stabilizing action.