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Phys Med Biol ; 58(2): 373-91, 2013 Jan 21.
Article in English | MEDLINE | ID: mdl-23257566

ABSTRACT

Understanding the influence of exposure of biological systems to THz radiation is becoming increasingly important. There is some evidence to suggest that THz radiation can influence important activities within mammalian cells. This study evaluated the influence of the high peak power, low average power THz radiation produced by the ALICE (Daresbury Laboratory, UK) synchrotron source on human epithelial and embryonic stem cells. The cells were maintained under standard tissue culture conditions, during which the THz radiation was delivered directly into the incubator for various exposure times. The influence of the THz radiation on cell morphology, attachment, proliferation and differentiation was evaluated. The study demonstrated that there was no difference in any of these parameters between irradiated and control cell cultures. It is suggested that under these conditions the cells are capable of compensating for any effects caused by exposure to THz radiation with the peak powers levels employed in these studies.


Subject(s)
Cell Differentiation/radiation effects , Embryonic Stem Cells/cytology , Embryonic Stem Cells/radiation effects , Epithelial Cells/cytology , Epithelial Cells/radiation effects , Terahertz Radiation/adverse effects , Cell Adhesion/radiation effects , Cell Line , Cell Proliferation/radiation effects , Humans
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