Subject(s)
Blood Pressure , Cerebrovascular Circulation , Hypoxia/physiopathology , Seizures/physiopathology , Adaptation, Biological , Animals , Hypoxia/blood , Male , Rats , Rheology , Seizures/bloodABSTRACT
Effect of single and chronic irradiation on factors of hamsters natural immunity such as complement, lysozyme and antibodies in norm and in the cestode invasion has been investigated. Significant phase changes in the complement activity level, lysozyme content and specific antibodies titre have been shown to occur in hamster blood under the influence of ionizing radiation. Cestode invasion in irradiated host organism increases the negative effect of ionizing radiation on the hamster immune system.
Subject(s)
Hymenolepiasis/immunology , Radiation Injuries, Experimental/immunology , Animals , Complement System Proteins/analysis , Cricetinae , Hymenolepiasis/complications , Hymenolepiasis/parasitology , Hymenolepis/growth & development , Immunity, Innate/radiation effects , Intestines/parasitology , Male , Muramidase/blood , Radiation Injuries, Experimental/complications , Radiation Injuries, Experimental/parasitologySubject(s)
Antigens, Helminth/isolation & purification , Diphyllobothrium/immunology , Animals , Antibodies, Helminth/analysis , Antigens, Helminth/immunology , Antigens, Surface/immunology , Antigens, Surface/isolation & purification , Epitopes/immunology , Epitopes/isolation & purification , Immunization , Immunodiffusion/methods , Mercaptoethanol , Mercaptoethylamines , Rabbits , Time FactorsABSTRACT
A new method of obtaining the diphyllobothriid surface antigens has been developed. It allows to obtain antigens with the increased content of the surface components of worm strobila. It was found that the antigens from extracts I are relatively more active than the antigens from extracts II and III.