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1.
Sci Rep ; 11(1): 10088, 2021 05 12.
Article in English | MEDLINE | ID: mdl-33980922

ABSTRACT

Identifying vital nodes in networks exhibiting a community structure is a fundamental issue. Indeed, community structure is one of the main properties of real-world networks. Recent works have shown that community-aware centrality measures compare favorably with classical measures agnostic about this ubiquitous property. Nonetheless, there is no clear consensus about how they relate and in which situation it is better to use a classical or a community-aware centrality measure. To this end, in this paper, we perform an extensive investigation to get a better understanding of the relationship between classical and community-aware centrality measures reported in the literature. Experiments use artificial networks with controlled community structure properties and a large sample of real-world networks originating from various domains. Results indicate that the stronger the community structure, the more appropriate the community-aware centrality measures. Furthermore, variations of the degree and community size distribution parameters do not affect the results. Finally, network transitivity and community structure strength are the most significant drivers controlling the interactions between classical and community-aware centrality measures.

2.
IEEE J Biomed Health Inform ; 20(6): 1640-1649, 2016 11.
Article in English | MEDLINE | ID: mdl-26259204

ABSTRACT

Biomedical information systems (BIS) require consideration of three types of variability: data variability induced by new high throughput technologies, schema or model variability induced by large scale studies or new fields of research, and knowledge variability resulting from new discoveries. Beyond data heterogeneity, managing variabilities in the context of BIS requires extensible and dynamic integration process. In this paper, we focus on data and schema variabilities and we propose an integration framework based on ontologies, master data, and semantic annotations. The framework addresses issues related to: 1) collaborative work through a dynamic integration process; 2) variability among studies using an annotation mechanism; and 3) quality control over data and semantic annotations. Our approach relies on two levels of knowledge: BIS-related knowledge is modeled using an application ontology coupled with UML models that allow controlling data completeness and consistency, and domain knowledge is described by a domain ontology, which ensures data coherence. A system build with the eClims framework has been implemented and evaluated in the context of a proteomic platform.


Subject(s)
Medical Informatics/methods , Proteomics/methods , Semantics , Data Curation , Databases, Factual , Humans
3.
Comput Soc Netw ; 3(1): 5, 2016.
Article in English | MEDLINE | ID: mdl-29355230

ABSTRACT

Influence in Twitter has become recently a hot research topic, since this micro-blogging service is widely used to share and disseminate information. Some users are more able than others to influence and persuade peers. Thus, studying most influential users leads to reach a large-scale information diffusion area, something very useful in marketing or political campaigns. In this study, we propose a new approach for multi-level influence assessment on multi-relational networks, such as Twitter. We define a social graph to model the relationships between users as a multiplex graph where users are represented by nodes, and links model the different relations between them (e.g., retweets, mentions, and replies). We explore how relations between nodes in this graph could reveal about the influence degree and propose a generic computational model to assess influence degree of a certain node. This is based on the conjunctive combination rule from the belief functions theory to combine different types of relations. We experiment the proposed method on a large amount of data gathered from Twitter during the European Elections 2014 and deduce top influential candidates. The results show that our model is flexible enough to to consider multiple interactions combination according to social scientists needs or requirements and that the numerical results of the belief theory are accurate. We also evaluate the approach over the CLEF RepLab 2014 data set and show that our approach leads to quite interesting results.

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