1.
Org Lett
; 10(4): 685-7, 2008 Feb 21.
Article
in English
| MEDLINE
| ID: mdl-18198882
ABSTRACT
A simple, one-pot procedure that converts 5,15-substituted porphyrins into the corresponding meso-formylated porphyrins has been developed. The method, based on a new synthetic concept for functionalized porphyrins utilizing the (2-pyridyldimethylsilyl)methyl group as a latent formyl functionality, affords the desired product in good yield and is especially appropriate for the direct formylation of free base porphyrins, which has never been achieved by known methods.