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1.
Opt Express ; 28(15): 22266-22275, 2020 Jul 20.
Article in English | MEDLINE | ID: mdl-32752492

ABSTRACT

The problem of a vertical electric dipole radiating above a periodic multilayer whose unit cell comprises a layer of a topological insulator (TI) and a columnar thin film (CTF) was solved in order to investigate the left/right asymmetry of the total electric field in the far zone in the half-space containing the dipole. Occurring in a wide range of the polar observation angle, the left/right asymmetry of Eϕ is due to both the CTFs and the TI layers. Occurring in a narrow range of the polar observation angle, the left/right asymmetry of Eθ is entirely due to the TI layers. For presently available values of the magnitude of the surface admittance γTI of TIs, significant left/right asymmetry occurs if the number of unit cells in the periodic TI/CTF multilayer is high enough.

2.
Appl Opt ; 58(7): 1724-1732, 2019 Mar 01.
Article in English | MEDLINE | ID: mdl-30874207

ABSTRACT

Very weak left/right asymmetry in reflection and transmission is offered by a layer of a topological insulator on top of a layer of an anisotropic dielectric material, but it can be enhanced very significantly by using a periodic multilayer of both types of materials. This is an attractive prospect for realizing one-way terahertz devices, because both types of materials can be grown using standard physical-vapor-deposition techniques.

3.
Electromagn Biol Med ; 33(4): 289-95, 2014 Dec.
Article in English | MEDLINE | ID: mdl-23977831

ABSTRACT

We evaluated the effects, on cultured human SaOS-2 cells, of exposures to the low frequency (LF) electric signal (60 kHz sinusoidal wave, 24.5 V peak-to-peak voltage, amplitude modulated by a 12.5 Hz square wave, 50% duty cycle) from an apparatus of current clinical use in bone diseases requiring regenerating processes. Cells in flasks were exposed to a capacitively coupled electric field giving electric current density in the sample of 4 µA/cm(2). The whole expressed cellular mRNAs were systematically analyzed by "DNA microchips" technology to identify all individual species quantitatively affected by field exposure. Comparisons were made between RNA samples from exposed and control sham-exposed cells. Results indicated that immediately and 4 h after exposure there were almost no differentially modulated mRNA species. However, samples obtained at 24 h after exposure showed a small number of limitedly differential signals (7 down-regulated and 3 up-regulated with a cut-off value of ±1.5; 38 and 11, respectively, with a cut-off value of ±1.3), which included mostly mRNA encoding transcription factors and DNA binding proteins. Nevertheless, in identical experimental conditions, we previously demonstrated enzymatic changes of alkaline phosphatase occurring immediately after exposure and declining in a few hours. Therefore, since enzymatic changes occur before those observed at gene regulation level, it is conceivable that only earlier effects are directly due the treatment and then these effects are later able to affect gene expression only indirectly.


Subject(s)
Bone and Bones/cytology , Electromagnetic Fields , Gene Expression Regulation/radiation effects , Bone and Bones/radiation effects , Cell Line, Tumor , Cell Proliferation/radiation effects , Cell Survival/radiation effects , Humans , RNA, Messenger/genetics , RNA, Messenger/metabolism , Time Factors
4.
Bioelectromagnetics ; 32(2): 113-9, 2011 Feb.
Article in English | MEDLINE | ID: mdl-21225888

ABSTRACT

Low-frequency (LF) electric fields (EFs) are currently used in clinical therapies of several bone diseases to increase bone regenerative processes. To identify possible molecular mechanisms involved in these processes, we evaluated the effects on cell cultures of 1 h exposures to the signal generated by an apparatus of current clinical use (frequency 60 kHz, frequency of the modulating signal 12.5 Hz, 50% duty cycle, peak-to-peak voltage 24.5 V). Two different human cell lines, bone SaOS-2 and liver HepG2, were used. Exposures significantly increased alkaline phosphatase (ALP) enzymatic activity in both cell lines. The increase was about 35% in SaOS-2 cells and about 80% in HepG2 cells and occurred in the first 4 h after exposure and decreased to almost no change by 24 h. Since ALP represents a typical marker of bone regeneration, these results represent a first molecular evidence of biological effects from 60 kHz EF exposures. The finding of similar effects in cells derived from two different tissues more likely indicates the effective operation of the mechanism in living organisms.


Subject(s)
Alkaline Phosphatase/metabolism , Electric Stimulation Therapy/instrumentation , Cell Survival , Hep G2 Cells , Humans , Time Factors
5.
Bioinspir Biomim ; 6(1): 014002, 2011 Mar.
Article in English | MEDLINE | ID: mdl-21183779

ABSTRACT

Multifrequency numerical simulations of the light-coupling efficiency of a prismatic bioinspired compound lens (BCL) of silicon atop a thick silicon substrate were carried out within the framework of geometrical optics. Comparison was made with untextured and groove-textured silicon substrates as well as with untextured silicon substrates with a double-layer anti-reflection (DLAR) coating. Taking into account the broadband nature and the sea-level spectral irradiance of the insolation flux, and averaging over all admissible directions and both linear polarization states of the incident light, we found that the light-coupling efficiency can be almost doubled with respect to the untextured silicon substrate and enhanced by about a third with respect to a DLAR-coated untextured silicon substrate, by adopting a DLAR-coated silicon BCL.


Subject(s)
Biomimetic Materials , Compound Eye, Arthropod/physiology , Diptera/physiology , Electric Power Supplies , Lens, Crystalline/physiology , Refractometry/instrumentation , Solar Energy , Animals , Computer Simulation , Computer-Aided Design , Equipment Design , Equipment Failure Analysis , Lenses , Models, Biological
6.
Bioinspir Biomim ; 5(2): 026002, 2010 Jun.
Article in English | MEDLINE | ID: mdl-20479523

ABSTRACT

Inspired by the apposition compound eyes of many dipterans, we formulated a fractal scheme to design prismatic lenses to improve the performance of silicon solar cells. We simulated the absorption of light, both directly illuminating and diffuse, using the geometrical-optics approximation. We found that properly designed bioinspired compound lenses (BCLs) can significantly improve the light-harvesting capabilities of silicon solar cells. The degree of improvement will depend on the material chosen to make the BCLs as well as the operating conditions.


Subject(s)
Biomimetic Materials , Compound Eye, Arthropod/physiology , Diptera/physiology , Electric Power Supplies , Lens, Crystalline/physiology , Lenses , Refractometry/instrumentation , Animals , Computer Simulation , Computer-Aided Design , Equipment Design , Equipment Failure Analysis , Models, Biological , Solar Energy
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