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Z Geburtshilfe Perinatol ; 197(3): 144-7, 1993.
Article in German | MEDLINE | ID: mdl-7690173

ABSTRACT

The etiology of fetal arrhythmias is still unknown. We therefore did a research for immunologic causes: antimyolemmal antibodies (AMLA) in mothers and umbilical cord serum resulting from secondary immunopathogenesis caused by myocarditis of the mother. Is there a correlation between immunological and clinical findings giving a possible explanation for fetal arrhythmias? In 21 cases mothers and umbilical cord serum was investigated for AMLA; 16 with fetal atrial premature beats, 4 with fetal tachycardia and 1 with fetal bradyarrhythmia. From 16 mothers with fetal atrial premature beats had 12 AMLA, from these were in 4 cases in the umbilical cord serum AMLA. In 4 cases of fetal tachycardia we found in 1 case AMLA in mothers and umbilical cord serum. In the other 3 cases accessory pathways have been the cause for tachycardia. From 19 healthy persons were found in 3 cases AMLA in mothers serum, umbilical cord serum was negative.


Subject(s)
Arrhythmias, Cardiac/congenital , Antibodies, Viral/analysis , Arrhythmias, Cardiac/immunology , Autoantibodies/analysis , Bradycardia/congenital , Bradycardia/immunology , Cardiac Complexes, Premature/congenital , Cardiac Complexes, Premature/immunology , Echocardiography , Female , Humans , Infant, Newborn , Myocarditis/immunology , Myocardium/immunology , Pregnancy , Pregnancy Complications, Cardiovascular/immunology , Tachycardia/congenital , Tachycardia/immunology , Tachycardia, Supraventricular/congenital , Tachycardia, Supraventricular/immunology , Ultrasonography, Prenatal
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