ABSTRACT
BACKGROUND: Radial scar is a breast lesion with mammographic and histologic features similar to carcinoma. We reviewed the characteristics of patients with radial scars to better understand these lesions and to determine the incidence of associated carcinoma. METHODS: Records for all patients undergoing diagnostic wire localized excisional breast biopsy from January 1993 to September 1999 were reviewed to identify those with histologic or mammographic evidence of radial scar. Clinical records, mammograms, and pathologic slides of these patients were reviewed. RESULTS: We identified 45 cases of radial scar: 10 patients had mammographic and histologic evidence of radial scar (group I), 29 only mammographic evidence (group II), and 6 only histologic evidence (group III). Breast cancer risk was similar in the three patient groups. Carcinoma was identified in 18 patients with mammographic radial scars. CONCLUSION: Mammographically detected radial scars were associated with carcinoma in 18 of 39 (46%) cases. Histologically identified radial scars are not associated with malignancy and should not be confused with mammographically identified lesions.
Subject(s)
Breast Diseases/diagnostic imaging , Breast Diseases/pathology , Adult , Aged , Aged, 80 and over , Breast Neoplasms/diagnostic imaging , Breast Neoplasms/pathology , Female , Fibrocystic Breast Disease/diagnostic imaging , Fibrocystic Breast Disease/pathology , Humans , Mammography , Middle Aged , Retrospective StudiesABSTRACT
Microcystic adnexal carcinoma is an uncommon cutaneous tumor with multiple synonyms. On cursory microscopic examination, the tumor mimics syringoma and other benign skin adnexal tumors. However, the asymmetric, infiltrative growth pattern clearly sets the lesion apart as carcinoma. The tumor is locally aggressive, with recurrences common, but regional metastases are rare. Histogenesis is controversial. Optimal treatment consists of complete surgical excision with clear surgical margins.
Subject(s)
Carcinoma, Skin Appendage/pathology , Eyelid Neoplasms/pathology , Skin Neoplasms/pathology , Adult , Carcinoma, Skin Appendage/surgery , Eyelid Neoplasms/surgery , Female , Humans , Skin Neoplasms/surgeryABSTRACT
Lung transplantation is a successful alternative treatment for a variety of end-stage lung diseases. The first 20 lung transplants performed in Louisiana between November 1990 and July 1994 are reported from Ochsner Foundation Hospital. Transplant procedures included 1 heart-lung, 11 bilateral sequential lung, and 8 single-lung transplants in 8 males and 11 females (1 retransplantation). The average age was 38 years (range 7-60), and the median waiting time was 34.5 days (range 1-329). Indications for transplant included emphysema, pulmonary fibrosis, pulmonary hypertension, cystic fibrosis, bronchiectasis, and bronchiolitis obliterans. Overall 1-year and 3-year survival were 65.0% and 58.5%, respectively. Infection was the major cause of morbidity and mortality. Rejection episodes were observed but treated successfully in all 20 patients. Lung transplantation has proved to be a successful treatment for a variety of severely limiting and terminal pulmonary conditions for patients in our state.
Subject(s)
Lung Diseases/surgery , Lung Transplantation/trends , Postoperative Complications/etiology , Adolescent , Adult , Cause of Death , Child , Female , Follow-Up Studies , Humans , Louisiana , Lung Diseases/mortality , Lung Transplantation/mortality , Male , Middle Aged , Postoperative Complications/mortality , Survival Rate , Treatment OutcomeABSTRACT
A case of nonHodgkin's lymphoma of the perianal region in a patient with AIDS is reported. The unusual features of AIDS-related lymphoma and the possible role of immunodeficiency increasing susceptibility to oncogenic viruses are discussed.
Subject(s)
Acquired Immunodeficiency Syndrome/complications , Anus Neoplasms/etiology , Lymphoma, Non-Hodgkin/etiology , Adult , Anus Neoplasms/pathology , Humans , Lymphoma, Non-Hodgkin/pathology , MaleSubject(s)
Aortic Aneurysm/complications , Aortic Dissection/complications , Ischemia/etiology , Liver/blood supply , Humans , Male , Middle AgedABSTRACT
Successful resection of an orbital angiolipoma in a 3-year-old child was performed. To our knowledge, this is the first report of angiolipoma in this site.
Subject(s)
Hemangioma/surgery , Lipoma/surgery , Orbital Neoplasms/surgery , Child, Preschool , Female , Hemangioma/diagnosis , Hemangioma/pathology , Humans , Lipoma/diagnosis , Lipoma/pathology , Magnetic Resonance Imaging , Orbital Neoplasms/diagnosis , Orbital Neoplasms/pathologyABSTRACT
Pure squamous neoplasia of the uterine corpus and uterine tube is explained by two possible mechanisms termed horizontal spread and vertical proliferation. We have reported a case of epidermoid carcinoma in situ of the uterine tube exemplifying the latter.
Subject(s)
Carcinoma in Situ/pathology , Carcinoma, Squamous Cell/pathology , Fallopian Tube Neoplasms/pathology , Neoplasms, Germ Cell and Embryonal/pathology , Uterine Neoplasms/pathology , Cell Division , Female , Humans , Middle AgedABSTRACT
To the authors' knowledge, this is the first reported case of any form of nephroblastomatosis occurring in an adult. Such a lesion is the presumed precursor of the rare Wilms' tumors that arise in adults.
Subject(s)
Kidney Neoplasms/epidemiology , Kidney/pathology , Wilms Tumor/epidemiology , Age Factors , Female , Humans , Kidney Neoplasms/pathology , Kidney Tubules/pathology , Middle Aged , Wilms Tumor/pathologyABSTRACT
Eleven cases of monomorphic adenoma of the salivary glands are interpreted as variants of pleomorphic adenomas (mixed tumors) that lack chondroid or myxomatous components. Nine of these tumors were in the parotid gland and two were on the hard palate. Monomorphic adenomas are usually encapsulated and frequently are partially cystic. Their histologic pattern may be confused with that of adenoid cystic carcinoma, but they grow in an expansile fashion and usually are monolobular. Histologically, they may be divided into trabecular-tubular, canalicular, and basaloid variants. Morphologically, they bear a resemblance to basaloid sweat-gland tumors (eccrine spiradenoma and cylindroma).
Subject(s)
Adenoma/pathology , Salivary Gland Neoplasms/pathology , Aged , Female , Humans , Male , Middle Aged , Palate/pathology , Parotid Neoplasms/pathologyABSTRACT
Neoplasia is the least common complication of Meckel's diverticulum. A case of partial obstruction of the small intestine due to adenocarcinoma arising in a Meckel's diverticulum is presented. The noteworthy feature of this case is the presence of neoplastic Paneth cells in the tumor.
