ABSTRACT
In a field study, the reduction in the anaesthetic effectiveness of Articain was investigated in relation to various influencing parameters. Both in the ZMK-Klinik (Dental Hospital) of Würzburg as well an in various independent practices, the local anaesthetic Articain was given to over 2000 patients in the course of dental treatment. With 12.1% of all test-subjects, inspite of the initial positive effectiveness upon application of the nerve-blocking anaesthetic, touch sensitivity and/or painfulness was established in the area concerned. Statistical evaluations of the recorded data of the test-subjects investigated showed a significantly higher quota of anaesthetic failure in the case of heavy cigarette consumption, chronic exposure to inhaled toxins as well as in the case of the intake of medicines of certain pharmaceutical types. Apart from that, a connection was also established between reduction in the effectiveness of the local anaesthetic and various treatments as well as the way in which the local anaesthetic was applied and the site of injection. Possible causes will be presented and discussed in relation to information from the literature on the subject.
Subject(s)
Anesthesia, Dental/methods , Anesthesia, Local/methods , Carticaine/pharmacokinetics , Smoking/adverse effects , Drug Interactions , Humans , Pain MeasurementSubject(s)
Fibroma/pathology , Mouth Mucosa/pathology , Mouth Neoplasms/pathology , Diagnosis, Differential , Female , Humans , Middle AgedABSTRACT
The healing of bony defects of the femur in guinea pigs is markedly accelerated after administration of 10 microgram of Flavichromin, an anabolic agent. Fluorescent microscopic studies showed an early transformation in the perivascular lamellar bones, particularly in the callus of the defect region.
Subject(s)
Femur/injuries , Quinones/therapeutic use , Wound Healing/drug effects , Animals , Bony Callus/drug effects , Guinea PigsABSTRACT
The advantages of a form for case history, clinical findings and therapeutical measures which meets the requirements of computerized documentation, are pointed out by means of individual groups of questions. In this connection, an example from maxillofacial traumatology, i.e. fractures of the mandible, is discussed. After discussion of the questionnaire, some results of the evaluation of the compiled data are presented.
Subject(s)
Computers , Germany, West , Humans , Surveys and Questionnaires , Tooth ExtractionSubject(s)
Fracture Fixation, Internal/methods , Mandibular Fractures/surgery , Bone Plates , HumansABSTRACT
In an experimental study using rabbits, bone is supercooled by means of liquid nitrogen flowing through a silicone chamber. The surrounding soft tissue is protected by a heating element of silicone. The histological findings in the stages of devitalization of osteocytes are described. X-rays and fluorescent labelling were used, searching for the time of total recalcification in supercooled bone.
