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1.
Sci Rep ; 13(1): 19695, 2023 11 11.
Article in English | MEDLINE | ID: mdl-37951980

ABSTRACT

Short stems are associated with a significantly lower blood loss (BL) compared to straight stems in total hip arthroplasty (THA). Different types of stems differ in design, fixation and level of femoral neck osteotomy. Therefore, we sought to evaluate the difference regarding the perioperative BL between two short stems with different designs in direct anterior approach (DAA). A total of 187 THA performed by a single surgeon were analysed. 107 patients received a neck-resecting (Group A) and 80 patients a neck-sparing short stem (Group B). Blood counts of the day before surgery and of two days after surgery were evaluated. Total blood volume and BL were calculated. Additionally, duration of surgery was analysed. The perioperative BL was significantly lower in Group B (451.4 ± 188.4 ml) compared to Group A (546.6 ± 232.7 ml; p = 0.002). The postoperative haematocrit (31.6 ± 3.7% vs. 30.4 ± 4.4%; p = 0.049) and haemoglobin-level (11.0 ± 1.3 g/dL vs. 10.4 ± 1.5 g/dL; p = 0.002) were significantly higher in Group B. Duration of surgery was significantly shorter in Group B (62.0 ± 11.4 min vs. 72.6 ± 21.8 min; p < 0.001). The use of a neck-sparing short stem leads to a significantly decreased BL compared to a neck-resecting short stem in DAA THA. A less extensively conducted capsular release necessary for optimal femoral exposition might lead to a lower perioperative BL and shorter durations of surgery.


Subject(s)
Arthroplasty, Replacement, Hip , Hip Prosthesis , Humans , Arthroplasty, Replacement, Hip/adverse effects , Hemorrhage , Femur Neck/surgery , Femur/surgery , Retrospective Studies
2.
Medicina (Kaunas) ; 59(2)2023 Feb 09.
Article in English | MEDLINE | ID: mdl-36837521

ABSTRACT

Background and Objectives: Noise exposure during total knee arthroplasty (TKA) has been demonstrated to exceed thresholds that are deemed as over-exposure by industry noise level standards. With orthopedic surgeons being at risk of suffering from Noise Induced Hearing Loss, the purpose of this pilot study was to evaluate the viability of the use of industry grade active noise cancelling headphones (ANCH) during TKA. Material and Methods: In this prospective pilot study, 10 TKA were performed. In five of these cases, surgeon, assistant, scrub nurse and anesthetist wore ANCH with automatic noise level dependent noise attenuation above 82 dB. A validated 14-item questionnaire was used after each case to evaluate the quality of communication, performance, teamwork and mental load. In seven cases a calibrated sound level meter was used to measure the operating theatre noise. Peak sound level (LApeak), A-weighted continuous sound level (LAeq) and A-weighted noise exposure averaged for an 8-h time-period (LEPd) were calculated. Results: There was no perceived benefit of ANCH for the surgeons (p = 0.648), assistants (p = 0.908) and scrub nurses (p = 0.251). There was an overall improvement observed by anesthetists (p = 0.001). A worse communication while wearing ANCH was reported by surgeons but not by the rest of the team. Average LApeak was 90.6 ± 3.2 dB(C), LAeq was 61.9 ± 1.0 dB(A) and LEPd was 53.2 ± 1.2 dB(A). Conclusions: Industry grade ANCH seem to provide no benefit for surgeons, assistants and scrub nurses during TKA, while anesthesiologists seem to benefit from the use of ANCH during TKA. Due to the limitations of this pilot study, further studies with larger study populations are necessary to adequately investigate the use of ANCH during TKA.


Subject(s)
Arthroplasty, Replacement, Knee , Surgeons , Humans , Pilot Projects , Prospective Studies , Noise
3.
Arch Orthop Trauma Surg ; 143(3): 1619-1626, 2023 Mar.
Article in English | MEDLINE | ID: mdl-35179634

ABSTRACT

PURPOSE: Minimally invasive approaches (MIS) in total hip arthroplasty (THA) show inconsistent findings regarding planning adherence in digital templating. The purpose of this study is to evaluate any difference in planning adherence between the direct anterior approach (DAA) and an anterolateral MIS approach (AL MIS) in cementless short stem THA. METHODS: A single surgeon series of 222 THAs in 208 patients with an uncemented short curved stem and a bi-hemispherical acetabular cup were screened for inclusion. A total of 118 THAs were implanted via the DAA and 72 THAs via the AL MIS were included. The planning adherence for the offset option, stem size and the acetabular cup were retrospectively evaluated. RESULTS: Planning adherence for cup size (perfect match: p = 0.763; ± 1 size: p = 0.124), offset option (0.125) and stem size (perfect match: p = 0.275; ± 1 size: p = 0.552) did not show any statistical significance. Preoperative diagnosis of avascular necrosis of the femoral head in AL MIS approach (OR 6.045; CI 1.153-31.696) or mild hip dysplasia in the general cohort poses (OR 11.789; CI 1.386-100.293) a significant risk for inadequate prediction of the offset option. CONCLUSION: digital templating for THA with an uncemented short curved stem and a bi-hemispherical acetabular cup show comparable results between a direct anterior approach and a minimally invasive anterolateral approach in supine position. Surgeons should be aware of a low planning adherence for this type of short stem in minimally invasive approaches. CONCLUSION: Digital templating for THA with an uncemented short curved stem and a bi-hemispherical acetabular cup show comparable results between a direct anterior approach and a minimally invasive anterolateral approach in supine position. Surgeons should be aware of a low planning adherence for this type of short stem in minimally invasive approaches.


Subject(s)
Arthroplasty, Replacement, Hip , Hip Dislocation, Congenital , Hip Prosthesis , Humans , Arthroplasty, Replacement, Hip/methods , Retrospective Studies , Acetabulum
4.
J Orthop Res ; 41(3): 641-648, 2023 03.
Article in English | MEDLINE | ID: mdl-35735256

ABSTRACT

To biomechanically evaluate the stability of a diaphyseal anchored, cementless stem in presence of a proximal periprosthetic femoral medial wall defect compared to the stability of the same stem in an intact femur. Twenty-two paired human cadaveric femora were pairwise assigned either to a fracture group, featuring a proximal medial wall defect involving 40% of the stems medial anchorage distance, or a control group with native specimens. The specimens were tested under a monotonically increasing cyclic axial loading protocol. Load, cycles, and multiples of the respective body weight at implant loosening was measured. Mean initial stiffness was 2243.9 ± 467.9 N/mm for the intact group and 2190.1 ± 474.8 N/mm for the fracture group. Mean load to loosening in the intact group was 3210.5 ± 1073.2 N and 2543.6 ± 576.4 N in the fracture group, with statistical significance. Mean cycles to loosening in the intact group were 27104.9 ± 10731.7 and 20431.5 ± 5763.7 in the fracture group, with statistical significance. Mean multiples of the resulting body weight at loosening in the intact group was 548.3 ± 158.5% and 441.4 ± 104% in the fracture group, with statistical significance. A medial wall defect involving 40% of the medial anchorage distance significantly decreases the axial stability of a diaphyseal anchored stem. However, mechanical failure occurred beyond physiological stress. At loosening rates of about 4 multiples of the body weight in the fracture group, a "safe zone" remains of a 0.5-fold body weight for maximum loads and twofold body weights for average loads.


Subject(s)
Arthroplasty, Replacement, Hip , Femoral Fractures , Hip Prosthesis , Periprosthetic Fractures , Humans , Arthroplasty, Replacement, Hip/methods , Prosthesis Design , Femur/surgery , Reoperation , Femoral Fractures/surgery
5.
BMC Musculoskelet Disord ; 23(1): 280, 2022 Mar 23.
Article in English | MEDLINE | ID: mdl-35321671

ABSTRACT

BACKGROUND: Periprosthetic femoral fractures (PFFs) represent a major cause for surgical revision after hip arthroplasty with detrimental consequences for patients. The Vancouver classification has been traditionally used since its introduction in 1995. The Unified Classification System (UCS) was described in 2014, to widen the spectrum by aiming for a more comprehensive approach. The UCS also aimed to replace the Vancouver classification by expanding the idea of the Vancouver classification to the whole musculoskeletal apparatus. After introduction of the UCS, the question was raised, whether the UCS found its place in the field of analysing PFFs. Therefore, this systematic review was performed to investigate, the use of the UCS compared to the established Vancouver classification. METHODS: Medline was searched for reports published between 1 January 2016 and 31 November 2020, without language restriction. Included were original articles, irrespective of the level of evidence and case reports reporting on a PFF and using either the Vancouver or the UCS to classify the fractures. Excluded were reviews and systematic reviews. RESULTS: One hundred forty-six studies were included in the analysis. UCS has not been used in a single registry study, giving a pooled cohort size of 3299 patients, compared to 59,178 patients in studies using the Vancouver classification. Since 2016, one study using UCS was published in a top journal, compared to 37 studies using the Vancouver classification (p=0.29). During the study period, the number of yearly publications remained stagnant (p=0.899). CONCLUSIONS: Despite valuable improvement and expansion of the latter UCS, to date, the Vancouver system clearly leads the field of classifying PFFs in the sense of the common use.


Subject(s)
Arthroplasty, Replacement, Hip , Femoral Fractures , Periprosthetic Fractures , Arthroplasty, Replacement, Hip/adverse effects , Femoral Fractures/etiology , Femur/surgery , Humans , Periprosthetic Fractures/diagnosis , Periprosthetic Fractures/etiology , Periprosthetic Fractures/surgery , Retrospective Studies
6.
Arch Orthop Trauma Surg ; 142(7): 1661-1668, 2022 Jul.
Article in English | MEDLINE | ID: mdl-34169356

ABSTRACT

PURPOSE: Digital templating shows reliable accuracy for straight stem systems. In recent years, the implantation of short stems through minimally invasive approaches has gained more popularity. Minimally invasive approaches (MIS) show the risk of undersizing femoral components. Therefore, we questioned the planning adherence for a curved short stem and a bi-hemispherical acetabular cup implanted through an anterolateral MIS approach. METHODS: A consecutive series of 964 hips (index surgery between 2014 and 2019) with Fitmore® curved short stem and Allofit/-S® acetabular cup (both ZimmerBiomet Inc, Warsaw, IN) were included. Preoperative digital templating was conducted anterior-posterior (AP) digital radiographs of the hip using mediCAD® version 5.1 (Hectec GmbH, Altdorf, Germany). The templates of acetabular and femoral components (offset option and stem size) were retrospectively evaluated for general adherence, and according to sex, BMI and planner's experience. RESULTS: Planning adherence for the exact offset option was 70.6 and 21.6% for exact offset option and stem size. Adherence for acetabular cup ± 1 size was 74.8%. A significant difference between male and female patients for the offset option could be found (p = 0.03, z = -2983). In 22.5% of male patients, an offset option one size higher and in 12.3% of female patients an offset option one size smaller than templated was used intraoperatively CONCLUSION: Digital templating for the Fitmore® stem in cementless THA with a minimally invasive anterolateral approach shows comparable planning adherence to the existing literature for this cementless short stem. However, a lower planning adherence was detected compared to conventional straight stem systems. In male patients, the femoral offset is frequently undersized and in female patients frequently oversized compared to the preoperative plan. Surgeons should be aware of this difficulty in digital templating for Fitmore® hip stem.


Subject(s)
Arthroplasty, Replacement, Hip , Hip Prosthesis , Female , Hip/surgery , Hip Joint/diagnostic imaging , Hip Joint/surgery , Humans , Male , Retrospective Studies , Sex Factors
7.
Arch Orthop Trauma Surg ; 142(5): 871-878, 2022 May.
Article in English | MEDLINE | ID: mdl-34076711

ABSTRACT

PURPOSE: Minimally invasive surgery using short stems in total hip arthroplasty gained more popularity. The differences in change of hip offset and implant positioning in minimally invasive approaches are not fully known. Therefore, this study was conducted to evaluate the difference in reconstruction of hip offset and implant positioning in direct anterior approach (DAA) and minimally invasive anterolateral approach (AL MIS). METHODS: A single surgeon series of 117 hips (117 patients; mean age 65.54 years ± 11.47; index surgery 2014-2018) were included and allocated into two groups: group A (DAA) with 70 hips and Group B (AL MIS) with 47 patients operated. In both groups the same type of cementless curved short hip stem and press fit cup was used. RESULTS: Both groups showed an equal statistically significant increase of femoral (p < 0.001) and decrease of acetabular offset (p < 0.001). Between both groups no statistically significant difference in offset reconstruction, leg length difference or implant positioning could be found. Leg length increased in both groups significantly and leg length discrepancy showed no difference (group A: - 0.06 mm; group B: 1.11 mm; p < 0.001). A comparable number of cups were positioned outside the target zone regarding cup anteversion. CONCLUSION: The usage of a curved short stem shows an equal reconstruction of femoro-acetabular offset, leg length and implant positioning in both MIS approaches. The results of this study show comparable results to the existing literature regarding change of offset and restoration of leg length. Malposition of the acetabular component regarding anteversion poses a risk.


Subject(s)
Arthroplasty, Replacement, Hip , Hip Prosthesis , Acetabulum/surgery , Aged , Arthroplasty, Replacement, Hip/methods , Humans , Leg Length Inequality/surgery
8.
Medicina (Kaunas) ; 57(11)2021 Nov 22.
Article in English | MEDLINE | ID: mdl-34833501

ABSTRACT

Background and objectives: Based on the preparation of 20 formalin-fixed anatomical cadavers, the feasibility of the anterior, minimally invasive approach to the hip joint was investigated in each side of the body. The hypothesis of the study was that the Lateral Femoral Cutaneous Nerve can be spared under the use of this approach. Materials and Methods: The anterior approach to the hip was performed via an incision of 8 cm. The position of the nerve was noticed in relation to the skin incision, and the distance was measured in millimeters. The nerves main, gluteal and femoral trunk were distinguished and investigated for injury. Results: No injury of the main trunk was noticed. The average distance of the main trunk to the skin incision was 14.9 and 15.05 mm in the medial direction, respectively (p < 0.001). Injury of the gluteal branch has to be considered at an overall rate of 40%. Conclusions: The anterior, minimally invasive approach to the hip joint can be performed without injury of the Lateral Femoral Cutaneous Nerve.


Subject(s)
Arthroplasty, Replacement, Hip , Cadaver , Femur , Hip Joint/surgery , Humans , Thigh
9.
Int Orthop ; 45(11): 2833-2841, 2021 11.
Article in English | MEDLINE | ID: mdl-34191091

ABSTRACT

PURPOSE: Obesity is associated with increased risk for surgical complications in total hip arthroplasty (THA). The impact of obesity on short-term complication in minimally invasive (MIS) anterolateral approach is not well known. Therefore, this study was conducted to evaluate the early complications within the first 90 days after THA using a MIS anterolateral approach with a short-curved stem stratified by Body Mass Index (BMI). PATIENTS AND METHODS: A single centre consecutive series of 1052 hips in 982 patients (index surgery 2014-2019) with a short-curved stem and press fit cup implanted using a MIS anterolateral approach in supine position were screened for inclusion. Inclusion criteria were defined as end-stage primary osteoarthritis of the hip. Eventually, 878 implantations in 808 patients were included and stratified by body mass index (BMI). Peri-operative complications, within the first 90 days after surgery, were retrospectively evaluated. RESULTS: Severely obese patients (BMI ≥ 35 kg/m2) and morbidly obese patients (BMI ≥ 40 kg/m2) demonstrated a significantly increased operation time (p < 0.001) and a higher risk for general surgical complications (p = 0.015) (odds ratio (OR) = 4.365; OR = 4.985), periprosthetic joint infection (PJI) (p = 0.001) (OR = 21.687; OR = 57.653), and revision (OR = 8.793; OR = 20.708). CONCLUSION: The risk for early PJI and overall surgical complications in MIS anterolateral approach is significantly increased in severely and morbidly obese patients. This leads to a significantly higher risk for revision surgery after index surgery within the first 90 days. A BMI above 35 kg/m2 is the clear threshold for increased risk of PJI in MIS anterolateral THA with a short curved stem. As the surgical complications are comparable to other approaches, MIS anterolateral short stem THA is also feasible with increasing BMI.


Subject(s)
Arthroplasty, Replacement, Hip , Obesity, Morbid , Postoperative Complications/epidemiology , Arthroplasty, Replacement, Hip/adverse effects , Humans , Minimally Invasive Surgical Procedures/adverse effects , Obesity, Morbid/complications , Reoperation , Retrospective Studies , Risk Factors
10.
J Orthop Traumatol ; 22(1): 19, 2021 May 21.
Article in English | MEDLINE | ID: mdl-34019194

ABSTRACT

PURPOSE: Minimally invasive (MIS) approaches in combination with short stems have gained popularity in recent years in total hip arthroplasty (THA). A decreased risk for periprosthetic femoral fractures (PFFs) is reported for cementless short-stem THA, but in contrast to other approaches, the risk factors for PFFs for short-stem THA using MIS anterolateral approach in supine position are not described in literature. METHODS: A single-center consecutive series of 1052 hips in 982 patients, performed between 2014 and 2019 with a short curved stem and a press fit using an MIS anterolateral approach in supine position, was retrospectively screened for inclusion. Fourteen patients were lost to follow-up. Therefore, 1038 THAs in 968 patients were included. Risk factors for intra- and postoperative PFFs within 90 days were analyzed. We investigated for sex, age, body mass index (BMI), diagnosis, and laterality. RESULTS: In total, 18 PFFs (1.7%) occurred. Intraoperative fracture occurred in ten cases ( 0.9%), with another eight cases (0.8%) occurring postoperatively. Increased American Society of Anesthesiologists (ASA) Score was a significant risk factor for PFF (p = 0.026), whereas sex (p = 0.155), age (p = 0.161), BMI (p = 0.996), and laterality (p = 1.000) were not. Seven PFFs (0.7%) required revision arthroplasty. CONCLUSION: Cementless short-stem THA using the MIS anterolateral approach is a procedure with a low number of PFFs within 90 days from index surgery. Fracture rates are comparable to other MIS approaches, and comparable femoral short stems are used. Age, sex, and BMI were not identified as risk factors of PFF, while risk for PFF increased with ASA Score. LEVEL OF EVIDENCE: Level IV.


Subject(s)
Arthroplasty, Replacement, Hip/methods , Hip Prosthesis/adverse effects , Periprosthetic Fractures/etiology , Adult , Aged , Aged, 80 and over , Female , Femoral Fractures/surgery , Femur/surgery , Humans , Intraoperative Complications/etiology , Intraoperative Complications/surgery , Male , Middle Aged , Postoperative Period , Reoperation , Retrospective Studies , Risk Factors , Young Adult
11.
Animals (Basel) ; 11(2)2021 Jan 22.
Article in English | MEDLINE | ID: mdl-33499389

ABSTRACT

The present study describes an outbreak of Pseudomonas (P.) aeruginosa mastitis in a 20-cow dairy herd where throughout genotyping of isolates reusable udder towels were identified as the source of infection. Sampling of cows during three herd surveys and bacteriological culturing showed that P. aeruginosa was isolated from nine cows with a total of 13 infected quarters. Mastitis occurred as mild clinical or subclinical infection. P. aeruginosa was additionally isolated from a teat disinfectant solution, containing N-(3-aminopropyl)-N-dodécylpropane-1,3-diamine 1 as active component, and microfiber towels used for pre-milking teat preparation. Disc diffusion antimicrobial resistance testing revealed that all isolates were susceptible to piperacillin, piperacillin-tazobactam, ceftazidime, cefepime, aztreonam, imipenem, meropenem, tobramycin, amikacin, and ciprofloxacin. Thirty-two isolates of milk samples and 22 randomly selected isolates of one udder towel and of the teat disinfectant solution were confirmed as P. aeruginosa with matrix-assisted laser desorption, ionization time-of-flight mass spectrometry (MALDI Tof MS). Isolates were further characterized with rep-PCR and randomly amplified polymorphic DNA (RAPD) as well as with multiple locus variable-number tandem repeat analysis (MLVA). Results obtained in this study suggested that one single strain was responsible for the whole outbreak. The transmission occurred throughout a contaminated teat cleaning solution as a source of infection. The farmer was advised to change udder-preparing routine and to cull infected cows.

12.
Vet Microbiol ; 235: 118-126, 2019 Aug.
Article in English | MEDLINE | ID: mdl-31282369

ABSTRACT

The aim of the present study was to investigate the diversity of methicillin-resistant Staphylococcus aureus (MRSA) that originated from Austrian companion animals during the last five-year period. A total of 90 non-repetitive MRSA isolates were obtained during diagnostic activities from autumn 2013 to autumn 2018. They originated from horses (n = 62), cats (n = 13), dogs (n = 10), rabbits (n = 2), a domestic canary, a zoo-kept hammer-headed bat (Hypsignathus monstrosus) and a semi-captive northern bald ibis (Geronticus eremita). Antimicrobial susceptibility testing was performed. All isolates were mecA-positive and mecC-negative. The isolates were genotyped by SCCmec, spa and dru typing, Multiple-Locus Variable number of tandem repeat Analyses (MLVA), S. aureus DNA microarray, and whole-genome sequencing (WGS). Eight sequence types (STs - ST398, ST5275 (new ST), ST225, ST8, ST22, ST152, ST1, and ST45), three SCCmec types (II, IV, and V), sixteen spa types (t003, t008, t011, t015, t032, t034, t1381, t1928, t1985, t223, t334, t355, t430, t6447, t6867, and t7105), fourteen dru types (dt10a, dt10az, dt10q, dt10r, dt11a, dt5e, dt6j, dt9a, dt9ak, dt9g, and four new types dt8as, dt7ak, dt4j, dt14n), and thirty-five MLVA types were detected. WGS-based core genome MLST (cgMLST) displayed five main clusters. Compared to the time period 2004-2013, the results of the present study show not only a higher diversity among the MRSA isolates within the population of Austrian companion animals, but also the introduction of new clones. Although ST398 isolates remained predominant, mainly due to high presence of this lineage among horses, increasing isolation rates of human-associated MRSA clones were observed in cats and dogs.


Subject(s)
Genetic Variation , Methicillin-Resistant Staphylococcus aureus/classification , Methicillin-Resistant Staphylococcus aureus/genetics , Pets/microbiology , Staphylococcal Infections/veterinary , Animals , Anti-Bacterial Agents/pharmacology , Bacterial Typing Techniques , Cats/microbiology , Dogs/microbiology , Genotype , Humans , Methicillin-Resistant Staphylococcus aureus/isolation & purification , Microbial Sensitivity Tests , Multilocus Sequence Typing , Oligonucleotide Array Sequence Analysis , Whole Genome Sequencing
13.
J Orthop ; 16(2): 182-186, 2019.
Article in English | MEDLINE | ID: mdl-30899147

ABSTRACT

OBJECTIVE: The aim of this study was to evaluate our long-term results with the Alloclassic CSF screw cup total hip arthroplasty system. This is the first study to provide a 30-year follow-up, based upon our 30-year follow up study on the Alloclassic stem system. METHODS: We reviewed 178 Alloclassic CSF screw cup systems, implanted in 171 patients from 1986 to 1987. The Zweymüller stem family was used in all cases. 136 patients had died over the last 30 years, so twenty-nine out of 35 patients being still alive, with a mean follow-up of 29,46 years (SD 0,48), were contacted by telephone and evaluated radiologically and clinically. Our loss-to-follow up was 17,14%. The mean age at follow-up was 83,01 years (72,4-95,2; SD 6,86). RESULTS: If the endpoint is defined as the removal of the cup for aseptic loosening (3 cases), the overall survival rate is 98,31%. If the endpoint is revision for any reason (27 cases), the survival rate is 84,83%. Eleven patients needed an exchange of head and liner. The mean time from implantation until change of head and liner was 21,44 years (SD 5,92). CONCLUSION: After 30 years of monitoring we can state that the evaluated system is very reliable in primary and secondary THA.

14.
Vet Microbiol ; 230: 138-144, 2019 Mar.
Article in English | MEDLINE | ID: mdl-30827379

ABSTRACT

The presence of the methicillin resistance gene mecC in coagulase-negative Staphylococcus spp. (CoNS) is scarce. The aim of this study was to characterize mecC-positive CoNS isolated from various wild and domestic animals. The presence of the mecC gene was screened in 4299 samples from wild animals and domestic animals. Fifteen coagulase-negative staphylococci, that displayed a cefoxitin-resistant phenotype, were tested mecC-positive by PCR. Antimicrobial susceptibility testing was performed for all isolates. The 15 isolates were genotyped by sequencing of the entire class E mec gene complex (blaZ-mecC-mecR1-mecI), the ccrA and ccrB recombinase genes and other determinants within the type XI SCCmec element. DNA microarray analysis was performed and five selected isolates were additionally whole genome sequenced and analyzed. S. stepanovicii (n = 3), S. caprae (n = 1), S. warneri (n = 1), S. xylosus (n = 1) and S. sciuri (n = 9) were detected. All but the S. sciuri isolates were found to be susceptible to all non-beta lactams. The entire class E mec gene complex was detected in all isolates but ccrA and ccrB genes were not identified in S. stepanovicii and S. xylosus. The genes erm(B) and fexA (n = 4, each) were the most predominant non-beta lactam resistance genes detected in the S. sciuri isolates. Even though the presence of the mecC gene among CoNS is a rare observation, this study further expands our knowledge by showing that the mecC gene, including its allotypes, are present in more staphylococcal species from different animal species than has been previously described.


Subject(s)
Bacterial Proteins/genetics , Methicillin Resistance/genetics , Staphylococcus/genetics , Staphylococcus/isolation & purification , Animals , Animals, Domestic/microbiology , Animals, Wild/microbiology , Anti-Bacterial Agents/pharmacology , Cefoxitin/pharmacology , Coagulase/genetics , DNA, Bacterial/genetics , Drug Resistance, Multiple, Bacterial , Goats/microbiology , Lynx/microbiology , Microbial Sensitivity Tests , Oligonucleotide Array Sequence Analysis , Polymerase Chain Reaction , Sheep/microbiology , Staphylococcus/drug effects
15.
J Orthop ; 15(1): 18-23, 2018 Mar.
Article in English | MEDLINE | ID: mdl-29187778

ABSTRACT

OBJECTIVE: The aim of this study was to evaluate our long-term results with the Zweymüller hochgezogen and SL total hip arthroplasty system. This is the first study to provide a 30-year follow-up. METHODS: We reviewed 186 Alloclassic stem systems (Zweymüller hochgezogen (112) and SL (74), implanted in 179 patients from 1986 to 1987.Two different types of cementless acetabular components were used.143 patients had died over the last 30 years, so thirty out of 36 patients being still alive, with a mean follow-up of 29,48 years (SD 0,51), were contacted by telephone and evaluated radiologically and clinically. Our loss-to-follow up was 16,7%. The mean age at follow-up was 83,57 years (72,4-95,2; SD 6,77). RESULTS: If the endpoint is defined as the removal of the stem for aseptic loosening (3 cases), the overall survival rate is 98,38%. If the endpoint is revision for any reason (27 cases), the survival rate is 85,48%. Eleven patients needed an exchange of head and liner. The mean time from implantation until change of head and liner was 21,44 years (SD 5,92).Most of the radiolucent lines and osteolytic zones were found in the proximal Gruen-zones 1 and 7 (69,7 and 21,2%). CONCLUSION: After 30 years of monitoring we can state that the evaluated system is very reliable in primary and secondary THA.

16.
J Orthop ; 14(1): 192-194, 2017 Mar.
Article in English | MEDLINE | ID: mdl-28115797

ABSTRACT

Wear debris seems to be the most likely reason for osteolysis in THA. The aim was to show the influence of head and acetabular liner revision surgery on osteolytic zones around the femoral component. Can head and inlay revision surgery reduce the size of the osteolytic zones around the femoral component? Which patients could benefit? 47 patients (51 hips), who had undergone THA head and inlay revision surgery between 1999 and 2011, were reviewed. The mean lifetime for the prosthesis was 15.1 years (8-26, standard deviation 4.5) and the mean follow-up for head and inlay was 39.2 months (12-113, standard deviation 30). The heads used in revision surgery were made of metal (26) and ceramics (25). In 36 cases a ultra-high-molecular-weight polyethylene inlay was taken, in 15 cases a regular PE-inlay. We compared the pre-surgical and follow-up anterior-posterior X-rays. The mean size of radiolucent areas before revision surgery was 147 sq.mm (5-389 sq.mm, standard deviation 115). Thirty-nine months (12-113) after surgery, their mean size was 145 sq.mm (7-604 sq.mm, standard deviation 124). Radiolucent zones exceeding 100 sq.mm could be reduced by an average of 28% in 18 out of 29 cases. The results showed an improvement in 29 out of 51 cases and a stop of progress in one case. According to the findings there may be a benefit for patients with big radiolucent areas.

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