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1.
The courage of one's convictions: the due diligence of Frances Oldham Kelsey at the FDA.
Scheindlin, Stanley.
Mol Interv ; 11(1): 3-9, 2011 Feb.
Article in English | MEDLINE | ID: mdl-21441115

Subject(s)
Thalidomide/adverse effects , Thalidomide/history , United States Food and Drug Administration/history , Animals , Drug Approval/history , Drug-Related Side Effects and Adverse Reactions/history , Ectromelia/chemically induced , History, 19th Century , History, 20th Century , Humans , United States
2.
Studies that keep rolling along: longitudinal analyses trade intervention for observations of change.
Scheindlin, Stanley.
Mol Interv ; 10(4): 190-6, 2010 Aug.
Article in English | MEDLINE | ID: mdl-20729484

Subject(s)
Epidemiologic Research Design , Longitudinal Studies/methods , Humans
3.
Episodes in the story of physostigmine.
Scheindlin, Stanley.
Mol Interv ; 10(1): 4-10, 2010 Feb.
Article in English | MEDLINE | ID: mdl-20124558

Subject(s)
Cholinesterase Inhibitors/history , Physostigmine/history , Cholinesterase Inhibitors/pharmacology , Cholinesterase Inhibitors/therapeutic use , Cholinesterase Inhibitors/toxicity , History, 18th Century , History, 19th Century , History, 20th Century , History, 21st Century , Humans , Physostigmine/pharmacology , Physostigmine/therapeutic use , Physostigmine/toxicity
4.
Our man in dorpat: Rudolf Buchheim and the birth of pharmacology.
Scheindlin, Stanley.
Mol Interv ; 10(6): 331-5, 2010 Dec.
Article in English | MEDLINE | ID: mdl-21263158

Subject(s)
Drug Discovery/history , Pharmacology/history , History, 18th Century , History, 19th Century , History, 20th Century , Humans , Male , Russia
5.
The problematic placebo.
Scheindlin, Stanley.
Mol Interv ; 9(3): 108-13, 2009 Jun.
Article in English | MEDLINE | ID: mdl-19592669

Subject(s)
Drug Evaluation , Placebo Effect , Research Design , Clinical Trials as Topic , Drug Evaluation/methods , Humans
6.
The flu in retrospect: etiology and immunization.
Scheindlin, Stanley.
Mol Interv ; 9(6): 284-90, 2009 Dec.
Article in English | MEDLINE | ID: mdl-20048132

Subject(s)
Immunization/history , Influenza Vaccines/history , Influenza Vaccines/immunology , Influenza, Human/history , Influenza, Human/virology , History, 19th Century , History, 20th Century , History, 21st Century , Humans , Influenza, Human/epidemiology , Influenza, Human/prevention & control
7.
The drug that launched a thousand sleds.
Scheindlin, Stanley.
Mol Interv ; 8(4): 152-8, 2008 Aug.
Article in English | MEDLINE | ID: mdl-18829839

Subject(s)
Diphtheria Antitoxin/history , Diphtheria Antitoxin/therapeutic use , Diphtheria/drug therapy , Diphtheria/history , Snow Sports/history , Alaska/epidemiology , Animals , Diphtheria/epidemiology , Dogs , Drug Industry/history , History, 19th Century , History, 20th Century , Humans , Immunization , United States
8.
Obesity, body image and diet drugs: 100 years of change.
Scheindlin, Stanley.
Mol Interv ; 8(2): 64-9, 2008 Apr.
Article in English | MEDLINE | ID: mdl-18403649

Subject(s)
Anti-Obesity Agents/therapeutic use , Body Image , Diet , Obesity/drug therapy , Anti-Obesity Agents/chemistry , Diet/history , History, 20th Century , History, 21st Century , History, Ancient , Humans , Obesity/history , Sympathomimetics/pharmacology , Thyroid Gland/drug effects , Weight Loss/drug effects
9.
The food and drug legislation of 1906.
Scheindlin, Stanley.
Mol Interv ; 8(1): 4-11, 2008 Feb.
Article in English | MEDLINE | ID: mdl-18332477

ABSTRACT

Pray for the welfare of government; since were it not for the fear of government; men would swallow each other alive.


Subject(s)
Legislation, Drug/history , Legislation, Food/history , United States Food and Drug Administration/organization & administration , History, 20th Century , Humans , Male , United States
10.
Something old... something blue.
Scheindlin, Stanley.
Mol Interv ; 8(6): 268-73, 2008 Dec.
Article in English | MEDLINE | ID: mdl-19144897

Subject(s)
Alzheimer Disease/drug therapy , Methylene Blue/chemistry , Methylene Blue/therapeutic use , Alzheimer Disease/history , Animals , Antimalarials/chemical synthesis , Antimalarials/chemistry , Antimalarials/history , Antimalarials/therapeutic use , History, 19th Century , History, 20th Century , History, 21st Century , Humans , Methemoglobinemia/drug therapy , Methemoglobinemia/history , Methylene Blue/analysis , Methylene Blue/history
11.
A new look at the xanthine alkaloids.
Scheindlin, Stanley.
Mol Interv ; 7(5): 236-42, 2007 Oct.
Article in English | MEDLINE | ID: mdl-17932410

Subject(s)
Alkaloids/history , Xanthines/history , Alkaloids/pharmacology , Alkaloids/therapeutic use , History, 18th Century , History, 19th Century , History, 20th Century , History, 21st Century , Humans , Xanthines/pharmacology , Xanthines/therapeutic use
12.
Medicine in the days of the caliphs.
Scheindlin, Stanley.
Mol Interv ; 7(2): 59-64, 2007 Apr.
Article in English | MEDLINE | ID: mdl-17468383

Subject(s)
History, Medieval , Medicine , Arabia , Humans , Islam , Jews , Physicians/history
13.
Clinical enzymology: enzymes as medicine.
Scheindlin, Stanley.
Mol Interv ; 7(1): 4-8, 2007 Feb.
Article in English | MEDLINE | ID: mdl-17339600

Subject(s)
Enzyme Therapy , Animals , Catalysis , Cystic Fibrosis/drug therapy , History, 20th Century , Humans , Inflammation/drug therapy , Legislation, Drug/history , Legislation, Drug/standards , Trypsin/therapeutic use , Wounds and Injuries/drug therapy
14.
Rare diseases, orphan drugs, and orphaned patients.
Scheindlin, Stanley.
Mol Interv ; 6(4): 186-91, 2006 Aug.
Article in English | MEDLINE | ID: mdl-16960139

Subject(s)
Legislation, Drug , Orphan Drug Production/legislation & jurisprudence , Patient Advocacy , Rare Diseases/drug therapy , Antipsychotic Agents/therapeutic use , Drug Approval , Drug Industry/legislation & jurisprudence , Haloperidol/therapeutic use , Humans , Pimozide/therapeutic use , United States , United States Food and Drug Administration/legislation & jurisprudence
15.
The fight against tuberculosis.
Scheindlin, Stanley.
Mol Interv ; 6(3): 124-30, 2006 Jun.
Article in English | MEDLINE | ID: mdl-16809472

Subject(s)
Mycobacterium/physiology , Tuberculosis/drug therapy , Tuberculosis/history , Animals , Antitubercular Agents/chemical synthesis , Antitubercular Agents/chemistry , Antitubercular Agents/isolation & purification , Antitubercular Agents/therapeutic use , BCG Vaccine/immunology , Depression/drug therapy , History, 15th Century , History, 16th Century , History, 17th Century , History, 18th Century , History, 19th Century , History, 20th Century , History, 21st Century , History, Medieval , Humans , Mycobacterium/drug effects , Smallpox/drug therapy , Smallpox/virology , Tuberculosis/metabolism , Tuberculosis/microbiology
16.
When she says yes, but he needs no: some reflections on nitric oxide.
Scheindlin, Stanley.
Mol Interv ; 6(1): 8-13, 2006 Feb.
Article in English | MEDLINE | ID: mdl-16507744

Subject(s)
Nitric Oxide/metabolism , Female , Humans , Male , Nitrates/metabolism , Nitrites/metabolism , Piperazines/pharmacology , Purines/pharmacology , Racial Groups , Sildenafil Citrate , Sulfones/pharmacology , Vasodilator Agents/metabolism
17.
Antimalarials: shortages and searches.
Scheindlin, Stanley.
Mol Interv ; 5(5): 268-72, 2005 Oct.
Article in English | MEDLINE | ID: mdl-16249521

Subject(s)
Antimalarials/history , Antimalarials/supply & distribution , Artemisia/chemistry , Artemisinins/therapeutic use , History, 20th Century , History, 21st Century , Humans , Hydrangea/chemistry , Methaqualone/therapeutic use , Piperidines , Plant Extracts/therapeutic use , Quinazolines/therapeutic use , Quinine/therapeutic use , World War II
18.
A century of ulcer medicines.
Scheindlin, Stanley.
Mol Interv ; 5(4): 201-6, 2005 Aug.
Article in English | MEDLINE | ID: mdl-16123533

Subject(s)
Anti-Ulcer Agents , Stomach Ulcer/drug therapy , Stomach Ulcer/history , Anti-Ulcer Agents/history , Anti-Ulcer Agents/therapeutic use , Gastric Mucosa/metabolism , Helicobacter pylori/metabolism , History, 19th Century , History, 20th Century , History, 21st Century , Humans , Stomach/pathology , Stomach Ulcer/microbiology
19.
The duplicitous nature of inorganic arsenic.
Scheindlin, Stanley.
Mol Interv ; 5(2): 60-4, 2005 Apr.
Article in English | MEDLINE | ID: mdl-15821152

Subject(s)
Arsenic Poisoning/history , Arsenic/toxicity , Antineoplastic Agents/pharmacology , Arsenic/chemistry , Arsenic/pharmacology , Arsenic Trioxide , Arsenicals/pharmacology , Chemistry, Inorganic , Environmental Exposure , History, 19th Century , History, 20th Century , Humans , Models, Chemical , Oxides/pharmacology
20.
Transdermal drug delivery: PAST, PRESENT, FUTURE.
Scheindlin, Stanley.
Mol Interv ; 4(6): 308-12, 2004 Dec.
Article in English | MEDLINE | ID: mdl-15616157

Subject(s)
Drug Administration Routes , Administration, Cutaneous , Humans , Molecular Weight , Skin Absorption
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