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1.
J Biol Regul Homeost Agents ; 34(5 Suppl. 3): 87-96. Technology in Medicine, 2020.
Article in English | MEDLINE | ID: mdl-33386038

ABSTRACT

There is a significant request for wearable systems for vital signs and athletic performance monitoring during sport practice, both in professional and non-professional fields. Respiratory rate is a rather neglected parameter in this field, but several studies show that it is a strong marker of physical exertion. The aim of the present scoping review is to evaluate the number and kind of existing studies on wearable technologies for the analysis of the chest wall movement for respiratory monitoring in sport and fitness. The review included studies investigating the use of contact-based wearable techniques for the detection of chest wall movement for respiratory monitoring during professional or amateur sport, during fitness and physical activity. The search was conducted on PubMed/Medline, Scopus and Google Scholar electronic databases using keywords. Data extracted were entered into a Microsoft Excel spreadsheet by the leading author and then double-checked by the second author. A total of 25 descriptive studies met the inclusion criteria. Few studies on small number of athletes were found, technologies were often evaluated without a reference system, data on participants are sometimes missing. To date, we are not able to draw conclusions on which is the best and most reliable device to use during sport practice.


Subject(s)
Abdominal Wall , Sports , Wearable Electronic Devices , Athletes , Exercise , Humans
2.
Annu Int Conf IEEE Eng Med Biol Soc ; 2019: 162-165, 2019 Jul.
Article in English | MEDLINE | ID: mdl-31945869

ABSTRACT

The treatment of choice for the unresectable cholangiocarcinoma is based on biliary decompression procedures. Despite stent placement is the standard of care, it is related to well-known complications. Hence, alternative techniques were proposed. Ideally, they should guarantee an adequate intraductal disobstruction, without injuring the surrounding tissues.This pre-clinical study aims to investigate the thermal effects of the laser ablation (LA) in the biliary tree, in terms of intraductal and surrounding tissue temperature achieved with different laser settings. The common bile ducts (in their upper and lower portions) of two pigs were ablated for 6 minutes with a diode laser at 3 W and 5 W. A custom-made laser applicator was used to obtain a circumferential ablation within the ducts. The intraductal temperature (Tid) was monitored by means of a fiber Bragg grating (FBG) sensor, while an infrared thermal camera monitored the T distribution in the surrounding tissues (Tsup). A maximum T difference of 65 °C and 57 °C was evidenced between the two power settings for the Tid measured in the upper and lower ducts, respectively. The mean difference between Tid and the averaged Tsup values was evaluated. At 5 W, a difference of 37±3 °C and 44±10 °C were obtained for the upper and lower ducts, respectively. At 3 W, a T difference of 2±1 °C was obtained for the upper biliary duct, while a difference of 8±1 °C was documented for the lower duct. Based on the results obtained in this preliminary study, the possibility to equip the laser probe with temperature sensor can improve the control and the safety of the procedure; this solution will guarantee the monitoring of the treatment while preserving the lumen and the surrounding structures.


Subject(s)
Bile Ducts , Laser Therapy , Animals , Lasers, Semiconductor , Swine , Temperature
3.
Annu Int Conf IEEE Eng Med Biol Soc ; 2019: 1851-1854, 2019 Jul.
Article in English | MEDLINE | ID: mdl-31946258

ABSTRACT

Thermal ablation is a minimally invasive technique used to induce a controlled necrosis of malignant cells by increasing the temperature in localized areas. This procedure needs an accurate and real-time monitoring of thermal effects to evaluate and control treatment outcome. In this work, a hyperspectral imaging (HSI) technique is proposed as a new and non-invasive method to monitor ablative therapy. HSI provides images of the target object in several spectral bands, hence the reflectance/absorbance spectrum for each pixel. This paper presents a preliminary and original HSI-based analysis of the thermal state in the in vivo porcine liver undergoing laser ablation. In order to compare the spectral response between treated and untreated areas of the organ, proper Regions of Interest (ROIs) were chosen on the hyperspectral images; for each ROI, the absorbance variation for the selected wavelengths (i.e., 630, 760, and 960nm, for deoxyhemoglobin, methemoglobin, and water respectively) was assessed. Results obtained during and after laser ablation show that the absorbance of the methemoglobin peaks increases up to 40% in the burned region with respect to the non-ablated one. Conversely, the relative change of deoxyhemoglobin and water peaks is less marked. Based on these results, absorbance threshold values were retrieved and used to visualize the ablation zone on the images. This preliminary analysis suggests that a combination of the absorbance information is essential to achieve a more accurate identification of the ablation region. The results encourage further studies on the correlation between thermal effects and the spectral response of biological tissues undergoing thermal ablation, for final clinical use.


Subject(s)
Ablation Techniques , Hyperthermia, Induced , Laser Therapy , Liver/surgery , Spectrum Analysis , Animals , Liver/diagnostic imaging , Necrosis , Swine
4.
Annu Int Conf IEEE Eng Med Biol Soc ; 2018: 5794-5797, 2018 Jul.
Article in English | MEDLINE | ID: mdl-30441652

ABSTRACT

Today clinicians may access large medical datasets, but very few systems have been designed to allow a practical and efficient exploration of data directly in critical medical environments such as operating rooms (OR). This work aims to assess during tests in laboratory and clinical settings a Surgery Touchless System (STS). This system allows clinicians to interact with medical images by using two different approaches: a gesture recognition and a voice recognition based system. These two methods are based on the use of a Microsoft Kinect and of a selective microphone, respectively. The STS allows navigating in a specifically designed interface, to perform several tasks, among others, to manipulate biomedical images. In this article, we assessed both the recognitions approaches in laboratory with 5 users. In addition, the STS was tested using only the voice-based recognition approach in clinical settings. The assessment was performed during three procedures by two interventionalradiologists. The five volunteers and the 2 radiologists filled two questionnaires to assess the system. The system usability was positively evaluated in laboratory tests. From clinical trials emerged that the STS was considered safe and useful by both the radiologists: they used the system an averaged number of times of 10 and 15 for patients, and found the system useful. These promising results allow considering this system useful for providing information not otherwise accessible and limiting the impact of human error during the operation. Future work will be focused on the use of the STS on a high number and different types of procedure.


Subject(s)
Computers , Image Interpretation, Computer-Assisted , Operating Rooms , Speech Recognition Software , User-Computer Interface , Gestures , Humans , Surgical Procedures, Operative
5.
Annu Int Conf IEEE Eng Med Biol Soc ; 2018: 1616-1619, 2018 Jul.
Article in English | MEDLINE | ID: mdl-30440702

ABSTRACT

In recent years, no-invasive and small size systems are meeting the demand of the new healthcare system, in which the vital signs monitoring is gaining in importance. In this context, Fiber Bragg grating (FBG) sensors are becoming very popular and FBG-based systems could be used for monitoring vital signs. At the same time, FBG could be able to sense chemical parameters by the polymer functionalization. The aim of our study was investigating the ability of a polymer-coated FBG-based probe for monitoring breathing patterns and respiratory rates. We tested the proposed FBG-based probe on 9 healthy volunteers during spirometry, the most common pulmonary function test. Results showed the high accuracy of the proposed probe to detect respiratory rate. The comparison between the respiratory rates estimated by the probe with the ones by the spirometer showed the absolute value of the percentage errors lower than 2.07% (in the 78% of cases <.91%). Lastly, a Bland Altman analysis was performed to compare the instantaneous respiratory rate values gathered by the spirometer and the FBG probe showing the feasibility of breath-by-breath monitoring by the proposed probe. Results showed a bias of 0.06± 2.90 $\mathrm{breaths}\square {\mathrm {min}}^{-1}$. Additionally, our system was able to follow the breathing activities and monitoring the breathing patterns.


Subject(s)
Fiber Optic Technology , Polymers , Respiratory Rate , Humans , Spirometry
6.
Annu Int Conf IEEE Eng Med Biol Soc ; 2018: 2865-2868, 2018 Jul.
Article in English | MEDLINE | ID: mdl-30440999

ABSTRACT

Wearable systems are gaining broad acceptance for monitoring physiological parameters in several medical applications. Among a number of approaches, smart textiles have attracted interest because they are comfortable and do not impair patients' movements. In this article, we aim at developing a smart textile for respiratory monitoring based on a piezoresistive sensing element. Firstly, the calibration curve of the system and its hysteresis have been investigated. Then, the proposed system has been assessed on 6 healthy subjects. The volunteers were invited to wear the system to monitor their breathing rate. The results of the calibration show a good mean sensitivity (i.e., approximately 0.11V·%-1); although the hysteresis is not negligible, the system can follow the cycles also at high rates (up to 36 cycle·min-1). The feasibility assessment on 6 volunteers (two trials for each one) shows that the proposed system can estimate with good accuracy the breathing rate. Indeed, the results obtained by the proposed system were compared with the ones collected with a spirometer, used as reference. Considering all the experiments, a mean percentage error was approximately 2%. In conclusion, the proposed system has several valuable features (e.g., the sensing element is lightweight, the sensitivity is high, and it is possible to develop comfortable smart textile); in addition, the promising performances considering both metrological properties and assessment on volunteers foster future tests focused on: i) the possibility of developing and system embedding several sensing elements, and ii) to develop a wireless acquisition system, to allow comfortable and long-term acquisition in both patients and during sport activities.


Subject(s)
Silver , Wearable Electronic Devices , Humans , Monitoring, Physiologic , Respiratory Rate , Textiles
7.
Annu Int Conf IEEE Eng Med Biol Soc ; 2017: 759-762, 2017 Jul.
Article in English | MEDLINE | ID: mdl-29059983

ABSTRACT

During recent decades epidural analgesia has gained widespread recognition in many applications. In this complex procedure, anaesthetist uses a specific needle to inject anesthetic into the epidural space. It is crucial the appropriate insertion of the needle through inhomogeneous tissues placed between the skin and the epidural space to minimize anesthetic-related complications (e.g., nausea, headache, and dural puncture). Usually, anaesthetists perform the procedure without any supporting tools, and stop pushing the syringe when they sense a loss of resistance (LOR). This phenomenon is caused by the physical properties of the epidural space: the needle breaks the ligamentum flavum and reaches the epidural space, in this stage the anaesthetist perceives a LOR because the epidural space is much softer than the ligamentum flavum. To support the clinician in this maneuver we designed a non-invasive system able to detect the LOR by measuring the pressure exerted on the syringe plunger to push the needle up to the epidural space. In a previous work we described the system and its assessment during in vitro tests. This work aims at assessing the feasibility of the system for LOR detection on a more realistic model (ex vivo pig model). The system was assessed by analyzing: its ability to hold a constant value (saturation condition) during the insertion of the needle, and its ability to detect the entrance within the epidural space by a decrease of the system's output. Lastly, the anaesthetist was asked to assess how the ex vivo procedure mimics a clinical scenario. The system reached the saturation condition during the needle insertion; this feature is critical to avoid false positive during the procedure. However, it was not easy to detect the entrance within the epidural space due to its small volume in the animal model. Lastly, the practitioner found real the model, and performed the procedures in a conventional manner because the system did not influence his actions.


Subject(s)
Anesthesia, Epidural , Animals , Epidural Space , Ligamentum Flavum , Needles , Syringes
8.
Annu Int Conf IEEE Eng Med Biol Soc ; 2017: 873-876, 2017 Jul.
Article in English | MEDLINE | ID: mdl-29060011

ABSTRACT

Thermal treatments are a valid clinical option in the management of several solid tumors. The difficulties to perform an accurate prediction improve the selectivity of the treatment effects represent the main hurdles in the spread of these techniques. Among other solutions, thermometric techniques are gaining acceptance in monitoring the effects of thermal treatments because they provide a clear end-point to obtain the complete removal of cancer without damaging the surrounding healthy tissue. This paper proposes a custom needle-like probe made of carbon fibers to embed seven fiber Bragg grating (FBG) sensors. This tool aims at a multiple points monitoring the tissue temperature during the thermal procedures, streamlining the FBG sensors insertion within the organ. After the description of the probe manufacturing, we reported the calibration of the seven sensors embedded within the probe, their step response, and the feasibility assessment of the probe for temperature monitoring during laser ablation on animal model (both in vivo and ex vivo). Results show that the proposed probe is easily maneuverable by the clinician, the sensors have a linear response with the temperature and a short step response; moreover, the probe allows measuring the temperature in seven points of the tissue; finally, it can be used during CTand MR-guided procedures without causing any artifact to the images. Thanks to these features the probe may be an useful solution to improve the safety and the outcomes of minimally invasive thermal ablation procedures, so to spread these procedures in the clinical field.


Subject(s)
Temperature , Animals , Carbon , Carbon Fiber , Fiber Optic Technology , Hyperthermia, Induced , Thermometers
9.
Annu Int Conf IEEE Eng Med Biol Soc ; 2017: 881-884, 2017 Jul.
Article in English | MEDLINE | ID: mdl-29060013

ABSTRACT

In mechanical ventilation, in particular when neonates are ventilated, it is crucial to accurately control the amount of the gas delivered to the patients. Mechanical ventilators are equipped with one of more flowmeters. The signal of the flowmeter is used as feedback to control the amount of gas delivered to the patients. Therefore, the accuracy of the flowmeter plays a crucial role in the accurate adjustment of the gas amount delivered by the ventilator. Among several solutions, variable area orifice meters (VAOMs) have several valuable features (e.g., good accuracy, and adequate frequency response), moreover they have the main advantage, with respect to orifice meters, related to the linearity of the response. Despite of their spread in this field, there are not studies focused on the analysis of the air temperature influence on VAOMs response. This study focuses on this topic by investigating the gas temperature influence on the response of a commercial VAOM. Experiments have been performed at low airflow (up to 1.5 L·min-1) and at four different temperatures (i.e., from 22°C to 38°C) covering the range of interest in the field of artificial ventilation. Results show that the response of the VAOM under test is sensitive to temperature: at constant airflow the higher the temperature the higher the sensor output. This analysis may be useful to add correction to sensor output in order to reject the influence of temperature, so to minimize the measurement error due to this factor.


Subject(s)
Flowmeters , Respiration, Artificial , Respiratory Physiological Phenomena , Temperature , Ventilators, Mechanical
10.
Annu Int Conf IEEE Eng Med Biol Soc ; 2017: 4423-4426, 2017 Jul.
Article in English | MEDLINE | ID: mdl-29060878

ABSTRACT

The interest on wearable textiles to monitor vital signs is growing in the research field and clinical scenario related to the increasing demands of long-term monitoring. Despite several smart textile-based solutions have been proposed for assessing the respiratory status, only a limited number of devices allow the respiratory monitoring in a harsh environment or in different positions of the human body. In this paper, we investigated the performances of a smart textile for respiratory rate monitoring characterized by 12 fiber optic sensors (i.e., fiber Bragg grating) placed on specific landmarks for compartmental analysis of the chest wall movements during quiet breathing. We focused on the analysis of the influence of sensor position on both peak-to-peak amplitude of sensors output and accuracy of respiratory rate measurements. This analysis was performed on two participants, who wore the textile in two positions (i.e., standing and supine). Bland-Altman analysis on respiratory rate showed promising results (better than 0.3 breaths per minute). Referring to the peak-to-peak output amplitude, the abdomen compartment showed the highest excursions in both the enrolled participants and positions. Our findings open up new approaches to design and develop smart textile for respiratory rate monitoring.


Subject(s)
Wearable Electronic Devices , Humans , Monitoring, Physiologic , Respiratory Rate , Textiles , Vital Signs
11.
Annu Int Conf IEEE Eng Med Biol Soc ; 2017: 4529-4532, 2017 Jul.
Article in English | MEDLINE | ID: mdl-29060904

ABSTRACT

Laser Ablation (LA) is a minimally invasive technique for tumor removal. The laser light is guided into the target tissue by a fiber optic applicator; thus the physical features of the applicator tip strongly influence size and shape of the tissue lesion. This study aims to verify the geometry of the lesion achieved by a tapered-tip applicator, and to investigate the percentage of thermally damaged cells induced by the tapered-tip fiber optic applicator. A theoretical model was implemented to simulate: i) the distribution of laser light fluence rate in the tissue through Monte Carlo method, ii) the induced temperature distribution, by means of the Bio Heat Equation, iii) the tissue injury, by Arrhenius integral. The results obtained by the implementation of the theoretical model were experimentally assessed. Ex vivo porcine liver underwent LA with tapered-tip applicator, at different laser settings (laser power of 1 W and 1.7 W, deposited energy equal to 330 J and 500 J, respectively). Almost spherical volume lesions were produced. The thermal damage was assessed by measuring the diameter of the circular-shaped lesion. The comparison between experimental results and theoretical prediction shows that the thermal damage discriminated by visual inspection always corresponds to a percentage of damaged cells of 96%. A tapered-tip applicator allows obtaining localized and reproducible damage close to spherical shape, whose diameter is related to the laser settings, and the simple theoretical model described is suitable to predict the effects, in terms of thermal damage, on ex vivo liver. Further trials should be addressed to adapt the model also on in vivo tissue, aiming to develop a tool useful to support the physician in clinical application of LA.


Subject(s)
Fiber Optic Technology , Animals , Hyperthermia, Induced , Laser Therapy , Lasers , Models, Theoretical , Swine
12.
Br J Anaesth ; 117 Suppl 1: i92-i96, 2016 Sep.
Article in English | MEDLINE | ID: mdl-27307290

ABSTRACT

BACKGROUND: Pressures (Pe) exerted by bronchial blockers on the inner wall of the bronchi may cause mucosal ischaemia. Our aims were as follows: (i) to compare the intracuff pressure (Pi) and Pe exerted by commercially available bronchial blockers in an in vitro and an ex vivo model; (ii) to investigate the influence of both the inflated intracuff volume and cuff diameter on Pe; and (iii) to estimate the minimal sealing volume (VSmin) and the corresponding Pe for each bronchial blocker studied. METHODS: The Pe exerted by seven commercial bronchial blockers was measured at different inflation volumes using a custom-designed system using in vitro and ex vivo animal models with two internal diameters (12 and 15 mm). RESULTS: In the same conditions, Pi was significantly lower than Pe (P<0.05), and Pe was higher in the in vitro model than in the ex vivo model. The Pe increased with the inflated volume, with use of the small-diameter model (P<0.05). Ex vivo models needed a higher minimal sealing volume than the in vitro models, and this volume increased with the diameter (e.g. the VSmin at a positive pressure of 25 cm H2O required a Pe ranging from 12 to 78 mm Hg on the 15 mm ex vivo model and from 66 to 110 mm Hg on the 12 mm ex vivo model). CONCLUSIONS: The Pi cannot be used to approximate Pe. The diameter of the model, the inflated volume, and the bronchial blocker design all influence Pe. A pressure higher than the critical ischaemic threshold (i.e. 25 mm Hg) was needed to prevent air leak around the cuff in the in vitro and ex vivo models.


Subject(s)
Bronchi/physiology , Intubation, Intratracheal/instrumentation , One-Lung Ventilation/instrumentation , Thoracic Surgical Procedures/instrumentation , Animals , Bronchi/anatomy & histology , Equipment Design , Humans , Intubation, Intratracheal/adverse effects , Intubation, Intratracheal/methods , Models, Anatomic , Models, Animal , One-Lung Ventilation/adverse effects , Pressure , Sus scrofa
13.
Annu Int Conf IEEE Eng Med Biol Soc ; 2016: 194-197, 2016 Aug.
Article in English | MEDLINE | ID: mdl-28268312

ABSTRACT

Epidural blockade procedures have gained large acceptance during last decades. However, the insertion of the needle during epidural blockade procedures is challenging, and there is an increasing alarming risk in accidental dural puncture. One of the most popular approaches to minimize the mentioned risk is to detect the epidural space on the base of the loss of resistance (LOR) during the epidural needle insertion. The aim of this paper is to illustrate an innovative and non-invasive system able to monitor the pressure exerted during the epidural blockade procedure in order to detect the LOR. The system is based on a Force Sensing Resistor (FSR) sensor arranged on the top of the syringe's plunger. Such a sensor is able to register the resistance opposed to the needle by the different tissues transducing the pressure exerted on the plunger into a change of an electrical resistance. Hence, on the base of a peculiar algorithm, the system automatically detects LOR providing visual and acoustic feedbacks to the operator improving the safety of the procedure. Experiments have been performed to characterize the measurement device and to validate the whole system. Notice that the proposed solution is able to perform an effective detection of the LOR.


Subject(s)
Anesthesia, Epidural/economics , Anesthesia, Epidural/methods , Cost-Benefit Analysis , Needles , Pressure , Algorithms , Calibration , Epidural Space/physiology , Female , Humans , Syringes
14.
Annu Int Conf IEEE Eng Med Biol Soc ; 2016: 344-347, 2016 Aug.
Article in English | MEDLINE | ID: mdl-28268347

ABSTRACT

Radiofrequency ablation (RFA) is a minimally invasive procedure used to treat tumors by means of hyperthermia, mostly through percutaneous approach. The tissue temperature plays a pivotal role in the achievement of the target volume heating, while sparing the surrounding healthy tissue from thermal damage. Several techniques for thermometry during RFA are investigated, most of them based on the use of single-point measurement system (e.g., thermocouples). The measurement of temperature map is crucial for the real-time control and fine adjustment of the treatment settings, to optimize the shape and size of the ablated volume. The recent interest about fiber optic sensors and, among them, fiber Bragg gratings (FBGs) for the monitoring of thermal effects motivated further investigation. In particular, the feature of FBGs to form an array of several elements, thus to be inscribed within the same fiber, allows the use of a single probe for the multi-points monitoring of the tissue temperature during RFA. Hence, the aim of this study is the development and characterization of a needle-like probe embedding an array of three FBGs, which was tested on pig liver during in vivo trials. The needle allows a safe and easy insertion of the fiber optic within the liver. It was inserted by ultrasound guidance into the liver, and monitored the change of tissue temperature during RFA controlled by the roll-off technique. Also the measurement error induced by breathing movements of the liver was assessed (less than 3 °C). Results encourage the use of the probe in clinical settings, as well as the improvement of some features, e.g., a higher number of FBGs for performing quasi-distributed measurement.


Subject(s)
Catheter Ablation/methods , Liver/surgery , Temperature , Animals , Electrodes , Female , Fiber Optic Technology , Humans , Liver/diagnostic imaging , Liver/pathology , Movement , Needles , Respiration , Sus scrofa , Ultrasonography
15.
Annu Int Conf IEEE Eng Med Biol Soc ; 2016: 3366-3369, 2016 Aug.
Article in English | MEDLINE | ID: mdl-28269025

ABSTRACT

Aim of this work is to design and develop an instrumented cylindrical object equipped with force sensors, which is able to assess grasping performance of both human and robotic hands. The object is made of two concentric shells between which sixteen piezoresistive sensors have been located in order to measure the forces applied by the hand fingers during grasping. Furthermore, a magneto-inertial unit has been positioned inside the object for acquiring information about object orientation during manipulation. A wireless communication between the electronic boards, responsible for acquiring the data from the sensors, and a remote laptop has been guaranteed. The object has been conceived in such a way to be adopted for evaluating both power and precision grasps and for measuring the forces applied by each finger of the hand. In order to evaluate object performance, a finite element analysis for estimating the deformation of the external shell for different force values has been carried out. Moreover, to evaluate object sensitivity, a static analysis of the force transmitted by the external shell to the underlying sensors has been performed by varying the thickness of the shells. The obtained preliminary results have validated the feasibility of using the developed object for assessing grasping performed by human and robotic hands.


Subject(s)
Hand Strength , Robotics/instrumentation , Adult , Calibration , Electronics/instrumentation , Equipment Design , Fingers , Hand , Humans , Male , Robotics/methods , Wireless Technology
16.
Annu Int Conf IEEE Eng Med Biol Soc ; 2016: 5174-5179, 2016 Aug.
Article in English | MEDLINE | ID: mdl-28269431

ABSTRACT

In this work, we investigated the temperature increment experienced by biological tissue during radiofrequency ablation (RFA). The measurements were performed by using two custom-made thermal probes based on fiber optic sensors (fiber Bragg gratings, FBGs). The two probes embed a total of 9 FBGs. Experiments were performed during RFA of an ex vivo healthy porcine liver. The RFA heating module was equipped with 5 thermocouples. Results show that the temperature increment close to the applicator (i.e., 0.6 cm-0.7 cm) reaches the temperature which is set as a target on the RFA module (i.e., approximately 100 °C). The distance from the applicator also has an impact on the dynamics of the heating phenomenon: at short distances the tissue temperature reaches a steady state condition after a few minutes, on the other hand the sensors placed at a distance ≥2cm did not reach the steady-state conditions during the 14-minute procedure. The multipoint temperature monitoring, which uses sensors at several distances from the applicator, can provide useful information regarding the boundary of damaged volume. This approach can be combined with the monitoring temperature system embedded in the heating equipment, to better control the damaged volume, and to improve the treatment outcomes.


Subject(s)
Catheter Ablation/instrumentation , Liver/surgery , Monitoring, Intraoperative/instrumentation , Surgery, Computer-Assisted , Tomography, X-Ray Computed , Animals , Fiber Optic Technology/instrumentation , Swine , Temperature
17.
Annu Int Conf IEEE Eng Med Biol Soc ; 2016: 5797-5800, 2016 Aug.
Article in English | MEDLINE | ID: mdl-28269572

ABSTRACT

Optical motion capture systems are widely used in biomechanics although have not been significantly explored for measuring volumes and volume variations yet. The aim of this study was to propose and test a completely novel procedure for the calibration of motion capture systems for the breathing analysis in terms of volume measurements, by the use of a tool consisting in an ad-hoc designed in-situ calibration device (CD) and two algorithms for calibration. Both the calibration tool and the calibration procedure performed in the range 0-2780mL on an Optoelectronic Plethysmography (OEP) system are presented. The CD delivered known volume (ΔVCD) variations to the OEP; the two algorithms performed the calibration by the comparison between ΔVCD and OEP recorded volume (ΔVOEP), in both static and dynamic conditions. Discrimination threshold, accuracy, precision and repeatability for the volume variation measurements have been evaluated, as well as the calibration curve of the OEP. OEP volume threshold of ±8.92mL was assessed; the volume measurement accuracy was always better than 6.0% of measured volume, and a volume repeatability of ±2.7mL was found. Lastly, the calibration curve was assessed to be ΔVOEP= 0.962·ΔVCD. Results demonstrate that the proposed calibration procedure can be useful to provide an in-situ accurate calibration of motion capture systems in the volume analysis, to optimize the hardware and the software of the available system for volume measurement as well as to establish the motion capture system appropriateness, in terms of technical suitability and data quality.


Subject(s)
Movement , Plethysmography/methods , Respiration , Algorithms , Calibration , Humans , Optical Devices , Plethysmography/instrumentation
18.
Annu Int Conf IEEE Eng Med Biol Soc ; 2016: 6054-6057, 2016 Aug.
Article in English | MEDLINE | ID: mdl-28269633

ABSTRACT

Comfortable and easy to wear smart textiles have gained popularity for continuous respiratory monitoring. Among different emerging technologies, smart textiles based on fiber optic sensors (FOSs) have several advantages, like Magnetic Resonance (MR)-compatibility and good metrological properties. In this paper we report on the development and assessment of an MR-compatible smart textiles based on FOSs for respiratory monitoring. The system consists of six fiber Bragg grating (FBG) sensors glued on the textile to monitor six compartments of the chest wall (i.e., right and left upper thorax, right and left abdominal rib cage, and right and left abdomen). This solution allows monitoring both global respiratory parameters and each compartment volume change. The system converts thoracic movements into strain measured by the FBGs. The positioning of the FBGs was optimized by experiments performed using an optoelectronic system. The feasibility of the smart textile was assessed on 6 healthy volunteers. Experimental data were compared to the ones estimated by an optoelectronic plethysmography used as reference. Promising results were obtained on both breathing period (maximum percentage error is 1.14%), inspiratory and expiratory period, as well as on total volume change (mean percentage difference between the two systems was ~14%). The Bland-Altman analysis shows a satisfactory accuracy for the parameters under investigation. The proposed system is safe and non-invasive, MR-compatible, and allows monitoring compartmental volumes.


Subject(s)
Monitoring, Physiologic/instrumentation , Respiratory Rate/physiology , Textiles , Humans
19.
Annu Int Conf IEEE Eng Med Biol Soc ; 2016: 6493-6496, 2016 Aug.
Article in English | MEDLINE | ID: mdl-28269734

ABSTRACT

In this work a spatially-resolved fiber optic temperature sensor has been characterized in a wide range of gradient applied on its active area (from -35 °C to +35 °C). Preliminary experiments to assess its feasibility for application in laser ablation have been performed. The sensor under test is a linearly chirped fiber Bragg grating (FBG), with 1.5 cm-length of active area. It can be considered as a chain of several FBGs, each able to sense local temperature. The sensor response to the gradient has been analyzed in terms of its spectrum width (full width at half maximum). There is a linear relationship between the full width at half maximum and the gradient, with a sensitivity of 0.0087 nm°C-1. The feasibility test using the linearly chirped FBG during laser ablation showed promising results: it is able to detect both the thermal gradients along is active area and the average temperature increment during the procedure.


Subject(s)
Fiber Optic Technology/instrumentation , Fiber Optic Technology/methods , Laser Therapy/methods , Liver/surgery , Animals , Equipment Design , Optical Fibers , Signal Processing, Computer-Assisted , Swine , Temperature
20.
Eur J Surg Oncol ; 41(12): 1699-705, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26433708

ABSTRACT

OBJECTIVE: The aim of the present study was to assess the temperature map and its reproducibility while applying two different MWA systems (915 MHz vs 2.45 GHz) in ex vivo porcine livers. MATERIALS AND METHODS: Fifteen fresh pig livers were treated using the two antennae at three different settings: treatment time of 10 min and power of 45 W for both systems; 4 min and 100 W for the 2.45 GHz system. Trends of temperature were recorded during all procedures by means of fiber optic-based probes located at five fixed distances from the antenna, ranging between 10 mm and 30 mm. Each trial was repeated twice to assess the reproducibility of temperature distribution. RESULTS: Temperature as function of distance from the antenna can be modeled by a decreasing exponential trend. At the same settings, temperature obtained with the 2.45 GHz system was higher than that obtained with the 915 MHz thus resulting into a wider area of ablation (diameter 17 mm vs 15 mm). Both systems showed good reproducibility in terms of temperature distribution (root mean squared difference for both systems ranged between 2.8 °C and 3.4 °C). CONCLUSIONS: When both MWA systems are applied, a decreasing exponential model can predict the temperature map. The 2.45 GHz antenna causes higher temperatures as compared to the 915 MHz thus, resulting into larger areas of ablation. Both systems showed good reproducibility although better results were achieved with the 2.45 GHz antenna.


Subject(s)
Catheter Ablation/methods , Liver/surgery , Microwaves/therapeutic use , Animals , Disease Models, Animal , Liver Diseases/surgery , Reproducibility of Results , Swine , Temperature
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