Free-living core body temperature monitoring using a wrist-worn sensor after COVID-19 booster vaccination: a pilot study.

Core body temperature (CBT) is a key vital sign and fever is an important indicator of disease. In the past decade, there has been growing interest for vital sign monitoring technology that may be embedded in wearable devices, and the COVID-19 pandemic has highlighted the need for remote patient monitoring systems. While wrist-worn sensors allow continuous assessment of heart rate and oxygen saturation, reliable measurement of CBT at the wrist remains challenging. In this study, CBT was measured continuously in a free-living setting using a novel technology worn at the wrist and compared to reference core body temperature measurements, i.e., CBT values acquired with an ingestible temperature-sensing pill. Fifty individuals who received the COVID-19 booster vaccination were included. The datasets of 33 individuals were used to develop the CBT prediction algorithm, and the algorithm was then validated on the datasets of 17 participants. Mean observation time was 26.4 h and CBT > 38.0 °C occurred in 66% of the participants. CBT predicted by the wrist-worn sensor showed good correlation to the reference CBT (r = 0.72). Bland-Altman statistics showed an average bias of 0.11 °C of CBT predicted by the wrist-worn device compared to reference CBT, and limits of agreement were - 0.67 to + 0.93 °C, which is comparable to the bias and limits of agreement of commonly used tympanic membrane thermometers. The small size of the components needed for this technology would allow its integration into a variety of wearable monitoring systems assessing other vital signs and at the same time allowing maximal freedom of movement to the user.

Correction: Schiboni et al. DynDSE: Automated Multi-Objective Design Space Exploration for Context-Adaptive Wearable IoT Edge Devices. Sensors 2020, 20, 6104.

Due to formal academic regulations, the affiliation of the university has been amended, and an "Acknowledgements" section has been added to the original publication [...].

DynDSE: Automated Multi-Objective Design Space Exploration for Context-Adaptive Wearable IoT Edge Devices.

We describe a simulation-based Design Space Exploration procedure (DynDSE) for wearable IoT edge devices that retrieve events from streaming sensor data using context-adaptive pattern recognition algorithms. We provide a formal characterisation of the design space, given a set of system functionalities, components and their parameters. An iterative search evaluates configurations according to a set of requirements in simulations with actual sensor data. The inherent trade-offs embedded in conflicting metrics are explored to find an optimal configuration given the application-specific conditions. Our metrics include retrieval performance, execution time, energy consumption, memory demand, and communication latency. We report a case study for the design of electromyographic-monitoring eyeglasses with applications in automatic dietary monitoring. The design space included two spotting algorithms, and two sampling algorithms, intended for real-time execution on three microcontrollers. DynDSE yielded configurations that balance retrieval performance and resource consumption with an F1 score above 80% at an energy consumption that was 70% below the default, non-optimised configuration. We expect that the DynDSE approach can be applied to find suitable wearable IoT system designs in a variety of sensor-based applications.