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1.
BJS Open ; 5(5)2021 09 06.
Article in English | MEDLINE | ID: mdl-34498667

ABSTRACT

BACKGROUND: In adults, intussusception has been considered traditionally to have an underlying aetiology. The aim of this study was to determine CT and clinical features of small-bowel intussusceptions that required surgical intervention. METHODS: Adult patients were identified in whom small-bowel intussusceptions were noted on CT images. The appearance, number, type (enteroenteric versus enterocolic), length and maximum short-axis diameter of intussusceptions, and presence of bowel obstruction (short-axis diameter of proximal small bowel greater than 3 cm) were analysed. The outcome was defined as surgical (complicated) or self-limiting (uncomplicated). Associations between complicated and uncomplicated intussusceptions and patient characteristics were investigated. RESULTS: Among 75 patients (56 male) with a mean age of 45 years, 103 intussusceptions were identified, of which 98 (95 per cent) were enteroenteric and 5 (5 per cent) enterocolic. Only 12 of 103 intussusceptions (12 per cent) in 12 of 75 (16 per cent) patients required surgical therapy and were considered to be complicated, with half of these having a neoplastic lead point. Length (P < 0.001), diameter (P < 0.001) and type (P = 0.002) of intussusception as well as presence of vessels (P = 0.023) within an intussusception on a CT scan, clinical symptoms (P = 0.007) and signs of bowel obstruction (P < 0.001) were associated with a surgical outcome. CONCLUSION: Clinical symptoms, signs of bowel obstruction, type and length of intussusception, and a visible tumour within an intussusception on CT scan were critical signs of complicated intussusception, requiring surgical intervention.


Subject(s)
Intussusception , Abdomen , Adult , Humans , Intestine, Small/diagnostic imaging , Intestine, Small/surgery , Intussusception/diagnostic imaging , Intussusception/surgery , Male , Middle Aged , Tomography, X-Ray Computed
2.
Sci Rep ; 9(1): 19876, 2019 12 27.
Article in English | MEDLINE | ID: mdl-31882716

ABSTRACT

The incidence and evolution of venous thrombosis adjacent to the ablation zone after percutaneous irreversible electroporation (IRE) were evaluated to identify potential risk factors in patients with hepatic malignancies. 205 venous structures (in 87 patients) within a ≤1.0 cm radius of the ablation zone were assessed after IRE of 112 hepatic lesions (74 primary, 38 secondary hepatic malignancies) by pre-interventional and post-interventional (1-3 days, 6 weeks and 3 months after IRE) contrast-enhanced magnetic resonance imaging. The relationships between venous thrombosis and clinical features were analysed using a binary logistic regression model. In 27 of 87 patients (31%), a total of 67 venous complications were noted during the 3 months follow-up. Thrombosis represented the most frequently observed complication (n = 47; 70.1%), followed by vessel narrowing (n = 20; 29.9%). 5 (10.6%) of 47 thromboses showed spontaneous regression 3 months after IRE. A small vessel diameter (p = 0.011) and post-interventional vessel narrowing (p = 0.006) were independently associated with delayed post-ablative thrombosis. Delayed venous thrombosis frequently occurs after IRE of hepatic malignancies. Pre-existing vessel narrowing and a small vessel diameter represent significant risk factors that require further surveillance and potentially therapeutic intervention.


Subject(s)
Carcinoma, Hepatocellular/complications , Carcinoma, Hepatocellular/pathology , Electroporation , Liver Neoplasms/complications , Liver Neoplasms/pathology , Venous Thrombosis/etiology , Venous Thrombosis/pathology , Adult , Aged , Aged, 80 and over , Female , Humans , Incidence , Logistic Models , Male , Middle Aged , Retrospective Studies , Risk Factors , Venous Thrombosis/complications
3.
Clin Hemorheol Microcirc ; 72(1): 85-93, 2019.
Article in English | MEDLINE | ID: mdl-30584122

ABSTRACT

PURPOSE: To assess the postprocedure findings after percutaneous irreversible electroporation (IRE) of hepatocellular carcinoma (HCC) in contrast-enhanced ultrasound (CEUS). MATERIALS AND METHODS: Percutaneous IRE was performed in a total of 22 patients with 24 HCC tumours following interdisciplinary tumour board review. The lesions were documented using CEUS before, immediately and within 24 hours after IRE. During follow-up CEUS was performed at 6 weeks and 3, 9, and 12 months after ablation. Two experienced radiologists evaluated the acquired CEUS image date in a consensus reading. RESULTS: Median tumour size before treatment was 13.7±4.8 mm (short axis) and 16.0±5.2 mm (long axis). All HCC lesions showed arterial hyperenhancement in CEUS. Median size of the ablation defect after ablation was 29.3±5.2 mm (short axis) and 31.6±5.6 mm (long axis). After IRE all tumours showed complete devascularization. The size of the ablation defects showed significant shrinkage and reduced peripheral enhancement in the course of follow-up. At 12 months follow-up the ablation defect size decreased to 16.7±4.3 mm (short axis) and 18.3±4.1 mm (long axis). CONCLUSION: CEUS showed a complete devascularization of HCC tumours after IRE. Post-intervetional peripheral enhancement returned to normal during follow-up and may represent zones of reversible damage of cellular integrity through electroporation. A significant shrinkage of the ablation defects during 12 month of follow-up was seen in all cases.


Subject(s)
Carcinoma, Hepatocellular/diagnostic imaging , Contrast Media/therapeutic use , Electroporation/methods , Liver Neoplasms/diagnostic imaging , Ultrasonography/methods , Carcinoma, Hepatocellular/pathology , Contrast Media/pharmacology , Female , Follow-Up Studies , Humans , Liver Neoplasms/pathology , Male , Middle Aged , Retrospective Studies , Time Factors
4.
Injury ; 47(8): 1608-12, 2016 Aug.
Article in English | MEDLINE | ID: mdl-27297706

ABSTRACT

INTRODUCTION: Mobile C-arm imaging is commonly used in operating rooms worldwide. Especially in orthopaedic surgery, intraoperative C-arms are used on a daily basis. Because of new minimally-invasive surgical procedures a development in intraoperative imaging is required. The purpose of this article is investigate if the choice of mobile C-arms with flat panel detector technology (Siemens Cios Alpha and Ziehm Vision RFD) influences image quality and dose using standard, commercially available test devices. MATERIALS AND METHODS: For a total of four clinical application settings, two zoom formats, and all dose levels provided, the transmission dose was measured and representative images were recorded for each test device. The data was scored by four observers to assess low contrast and spatial resolution performance. The results were converted to a relative image quality figure allowing for a direct image quality and dose comparison of the two systems. RESULTS: For one test device, the Cios Alpha system achieved equivalent (within the inter-observer standard error) or better low contrast resolution scores at significantly lower dose levels, while the results of the other test device suggested that both systems achieved similar image quality at the same dose. The Cios Alpha system achieved equivalent or better spatial resolution at significantly lower dose for all application settings except for Cardiac, where a comparable spatial resolution was achieved at the same dose. CONCLUSION: The correct choice of a mobile C-arm is very important, because it can lead to a reduction of the intraoperative radiation dose without negative effects on image quality. This can be a big advantage to reduce intraoperative radiation not only for the patient but also for the entire OR-team.


Subject(s)
Fluoroscopy/instrumentation , Monitoring, Intraoperative/instrumentation , Orthopedic Procedures , Radiation Dosage , Radiographic Image Interpretation, Computer-Assisted/instrumentation , X-Rays , Dose-Response Relationship, Radiation , Equipment Design , Humans , Intraoperative Period , Quality Control , Signal-To-Noise Ratio
5.
Sportverletz Sportschaden ; 29(4): 231-5, 2015 Dec.
Article in German | MEDLINE | ID: mdl-26574887

ABSTRACT

BACKGROUND: Injuries to the spinal cord are not only dreaded because of the high risks existing during the acute phase, but also because of their potential long-term sequelae. Horseback riding also poses a high risk of spinal injuries. We therefore evaluated the most frequent characteristics of accidents leading to long-term sequelae, the primary long-term discomfort resulting from such injuries caused by horseback riding accidents and the way injured persons changed their behaviour after the accidents. PATIENTS: Our study included all cases of horseback riding injuries registered in the Department of Trauma, Hand, Plastic and Restorative Surgery at the University Hospital of Ulm between May 2005 and October 2012. Sequelae of the accidents were examined via follow-up interviews by phone. These included questions about protective gear worn during the accident as well as behavioural changes after the injury. In addition, a spine-specific questionnaire based on the Visual Analogue Scale (VAS) was used to assess long-term complications. RESULTS: Overall, we recorded 50 cases of spinal injuries caused by horseback riding accidents over a time span of 7 years and 5 months. 41 (82 %) of the patients were female and 9 (18 %) were male. The average patient age was 32.0 ±â€Š15.2 years. All in all, the 50 patients sustained 84 injuries: 59 fractures and 25 other injuries such as distorsions or discoligamentous injuries. Most injuries were located in the lumbar spine (n = 43), corresponding to 51 % of all recorded injuries, followed by 32 % in the thoracic spine (n = 27) and 17 % in the cervical spine (n = 14). After sustaining a fracture to the spine, 9 out of 24 patients quit horseback riding. All patients used a helmet after the accident, but only 7 out of 15 used back protection. 11 out of 24 patients suffer from back pain while resting with a mean VAS score of 3.4 ±â€Š1.9. More than half (17 out of 24) have back pain while working with a VAS score of 4.8 ±â€Š2.2. CONCLUSION: The frequency and severity of back injuries sustained by horseback riders increases with age. This can be due to various reasons such as biomechanical factors. The low acceptance of back protection is remarkable.


Subject(s)
Back Pain/epidemiology , Horses , Protective Devices/statistics & numerical data , Spinal Fractures/epidemiology , Spinal Fractures/prevention & control , Sports Equipment/statistics & numerical data , Adult , Age Distribution , Animals , Back Pain/diagnosis , Back Pain/prevention & control , Causality , Comorbidity , Female , Germany/epidemiology , Humans , Lumbar Vertebrae/injuries , Male , Risk Factors , Sex Distribution , Spinal Fractures/diagnosis
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