ABSTRACT
Techniques for quantitatively describing the firing properties of neurons have been used to identify thalamic cells with a firing pattern which is correlated with EMG activity during tremor. By locating these cells relative to the anterior border of the somatosensory nucleus and the anterior commissure-posterior commissure line, it may be possible to select the optimal lesion site for the relief of parkinsonian tremor on a rational rather than an empirical basis.
Subject(s)
Neurons/physiology , Parkinson Disease/surgery , Stereotaxic Techniques , Thalamus/surgery , Tremor/surgery , Humans , Parkinson Disease/physiopathology , Thalamus/cytology , Tremor/physiopathologyABSTRACT
Stainless-steel cylinders of different pore size were implanted into the tibia, and small tubes, 500 micrometers diameter, of the same material into the iliac crests of 19 rabbits. It was found that after three weeks ingrowing bone tissue anchored the cylinders if the pore size was adequate. The same applied to the tubes. A stable implantation was the prerequisite for the ingrowth of fibre-bone trabeculae. Additionally, the use of fibrinogen adhesive system seems to be advantageous for this anchorage. These results were established by mechanical tensile tests and morphological examinations.