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Cancer Cell
; 23(3): 265-7, 2013 Mar 18.
Article
in English
| MEDLINE
| ID: mdl-23518342
ABSTRACT
Cancer stem cells display an epithelial-mesenchymal transition phenotype and are resistant to current therapies. In this issue of Cancer Cell, Dong and colleagues demonstrate that these phenotypes in basal-like breast cancer are promoted by a metabolic switch to glucose metabolism, resulting in decreased reactive oxygen species levels.