Cutaneous larva migrans in travelers: a prospective study, with assessment of therapy with ivermectin.

The purpose of this prospective study was to update epidemiological data on cutaneous larva migrans (CLM) and to assess the therapeutic efficacy of ivermectin. We performed the study between June 1994 and December 1998 at our travel clinic. Ivermectin (a single dose of 200 microg/kg) was offered to all the patients with CLM, and its efficacy and tolerability were assessed by a questionnaire. Sixty-four patients were enrolled. All were European and had stayed in tropical areas. After the patients had returned from their destinations, 55% had lesions occur within a mean of 16 days (range, 1-120 days; >1 month in 7 patients). The initial diagnosis was wrong in 55% of patients. The mean number of lesions was 3 (range, 1-15), and the main sites were the feet (48%) and buttocks (23%). The cure rate after a single dose of ivermectin was 77%. In 14 patients, 1 or 2 supplementary doses were necessary, and the overall cure rate was 97%. The median time required for pruritus and lesions to disappear was 3 and 7 days, respectively. No systemic adverse effects were reported. Physicians' knowledge of CLM, which can have a long incubation period, is poor. Single-dose ivermectin therapy appears to be effective and well tolerated, even if several treatments are sometimes necessary.

Geotrichum capitatum septicaemia in neutropenic patients: case report and review of the literature.

We report a case of systemic infection with Geotrichum capitatum in a patient with acute myeloid leukaemia. Three days before death, the patient developed acute renal failure, probably caused by occlusion of glomerula with hyphae of G. capitatum. Up until now, prophylaxis and treatment of infections caused by Geotrichum capitatum have not been established. However, the prophylactic administration of high-dose itraconazole and the therapeutic use of liposomal amphotericin B are subjects of discussion.

[Energy and nitrogen metabolism of pregnant and lactating sows and suckling piglets. 6. Comparative studies of energy and nitrogen metabolism of non-pregnant and pregnant sows]. / Untersuchungen zum Energie- und Stickstoffumsatz von Graviden und Laktierenden Sauen Sowie von Saugferkeln. 6. Mitteilung--Vergleichende Energie- und Stickstoffumsatzmessungen an güsten und graviden Sauen.

Aim of the studies was to attain new scientific findings for the influence of the physiological state of sows (non-pregnant and pregnant respectively) on energy and nitrogen metabolism. The experiments were carried out according to a 3 x 3 factorial experimental plan with 3 variants of litter number (1, 2 and 4) and 3 variants of energy supply (120, 100 and 80%). Within the variants the non-pregnant and pregnant sows were fed equally related to the metabolic live weight. The metabolism measurements run from the 1st to the 115th experimental and gestation day respectively. The methods of indirect calorimetry and slaughtering technique were applied. The chemical composition of the whole bodies of the non-pregnant sows was like that of the maternal bodies of the pregnant sows (dry matter 410 g/kg, protein 160 g/kg and fat 210 g/kg). The physiological state for the sows did not influence the nutrients digestibility (OM 77.0 and 76.7%) and the energy metabolizability. About conformable intakes of metabolizable energy (601 and 586 kJ/kg LW0.75.d) and of digestible nitrogen (0.77 and 0.75 g/kg LW0.75.d) in non-pregnant and pregnant sows resulted in higher deposition of energy (64 and 79 kJ/kg LW0.75.d) and of nitrogen (0.15 and 0.19 g/kg LW0.75.d) in the pregnant sows due to energy and nitrogen deposition in the conception products and in the reproductive organs. The energy maintenance requirement and the partial efficiency of the energy utilization for the deposition as well as the nitrogen maintenance requirement and the partial efficiency of the nitrogen utilization for the deposition in the non-pregnant and the pregnant sows were determined.

[Energy and nitrogen metabolism of pregnant and lactating sows and suckling piglets. 7. Energy and nitrogen metabolism in suckling piglets]. / Untersuchungen zum Energie- und Stickstoffumsatz von graviden und laktierenden Sauen sowie fon Saugferkeln. 7. Mitteilung--Energie und Stickstoffumsatz von Saugferkeln.

In 23 litters, each with 10 or 11 piglets, the energy and nitrogen metabolism was measured on base of 218 body analyses in suckling piglets and on base of 96 total metabolism experiments in early weaned piglets, combined with 134 body analyses. The studies were carried out as part of a complex experimental program for the factorial derivation of energy and protein requirement of piglets and for measuring the milk production of lactating sows. The energy maintenance requirement of suckling piglets (sow's milk nutrition, I) and of early weaned piglets (sow's milk replacement on the basis of cow's milk, II) amounted to 468 (I) and 451 kJ (II) metabolizable energy per kg LW0.75 . d, the utilization of of metabolizable energy for energy deposition to 70(I) and 72% (II). With mean live weight gains (LWG) of 161 and 162 g per animal and day the cost per kg LWG amounted to 19.9 and 20.4 MJ gross energy, 19.3 and 19.4 MJ metabolizable energy as well as 14.4 and 14.2 MJ net energy-fat in suckling and early weaned piglets resp. The mean energy content of the LWG amounted to 8.9 (I) and to 7.9 MJ/kg (II).

[Energy and nitrogen metabolism of pregnant and lactating sows and suckling piglets. 5. Energy and nitrogen metabolism of pregnant sows]. / Untersuchungen zum Energie- und Stickstoffumsatz von graviden und laktierenden Sauen sowie von Saugferkeln. 5. Mitteilung--Energie- und Stickstoffumsatz von graviden Sauen.

The energy and nitrogen metabolism of pregnant sows was measured with the method of indirect calorimetry in dependence on the number of gestation (1,2 and 4), on the energy supply (120, 100 and 80% of the requirement recommendation) and on the gestation stage. Values of maintenance requirement and of energy and nitrogen utilization for body deposition were calculated on the basis of results of energy and nitrogen metabolism. The energy maintenance requirement increased from 389 to 435 and 473 kJ metabolizable energy per kg LW0.75.d with rising number of gestation. The heat production increased from 85th to 115th day of gestation by 6%. The efficiency of the partial energy utilization for the energy deposition amounted to 66% on the average. The efficiency of the partial utilization of digestible nitrogen for the nitrogen deposition was calculated to 75%. The nitrogen maintenance requirement values amounted to 0.5 and 0.4 g digestible nitrogen per kg LW0.75.d in the 1st and 2nd half of gestation.

[Energy and nitrogen metabolism of pregnant and lactating sows in addition to the suckling piglets. 4. Chemical composition and energy content of the conception products, reproductive organs and the live weight gain or loss in pregnant or lactating sows]. / Untersuchungen zum Energie- und Stickstoffumsatz von graviden und laktierenden Sauen sowie von Saugferkeln. 4. Mitteilung--Chemische Zusammensetzung und Energiegehalt der Konzeptionsprodukte, der reproduktiven Organe und der Lebendmassezunahmen oder -abnahmen bei graviden und laktierenden Sauen.

The chemical composition and the energy content of the conception products, the reproductive organs and the live weight gains or losses of pregnant and lactating sows were determined in dependence on the litter number (1, 2 and 4) and the energy supply (120, 100 and 80% of requirement recommendation) of sows as well as on the course of gestation and lactation. The results will be used as a basis for factorial derivation of requirement recommendation. The deposition of protein and energy in the conception products in dependence on the time is characterized by an exponential function. The deposition of nutrients and energy in the conception products is increased with rising litter size. The deposition of nutrients and energy per fetus is lower in the litter number 1 than in the litter number 2 and 4. The energy supply in the selected limits has no significant influence on the litter size as well as on the intrauterine deposition of nutrients and energy. The litter number, the energy supply as well as the course of gestation and lactation influence considerably the weight, the chemical composition and the energy content in the mammary gland. The chemical composition and the energy content of the live weight gains or losses of pregnant and lactating sows are strong affected by the energy supply. The increased energy supply of the pregnant sows is connected with increased live weight gains and with increased contents of dry matter, fat and energy however decreased contents of protein in the live weight gains. The live weight losses of the lactating sows are connected with mobilisation of body fat and body protein. The proportion of body fat to body protein degradation is increased with increased losses of body weight. Regression equations are calculated for the relationships between course of gestation and lactation respectively and deposition of protein and energy in the conception products, reproductive organs and maternal live weight gains or losses of sows.

[Energy and nitrogen metabolism of pregnant and lactating sows and suckling piglets. 3. Chemical composition and energy content of the animal body fractions as well as portions of the animal body fractions of empty body of nonpregnant, pregnant and lactating sows]. / Untersuchungen zum Energie- und Stickstoffumsatz von graviden und laktierenden Sauen sowie von Saugferkeln. 3. Mitteilung--Chemische Zusammensetzung und Energiegehalt von Tierkörperfraktionen sowie Anteile der Tierkörperfraktionen am Leerkörper von güsten, graviden und laktierenden Sauen.

The study is based on the results obtained from the slaughter of 5 sows on the first day of pregnancy and the first day of the experiment respectively (pregnant and non-pregnant sows resp.), of 43 pregnant sows on the 56th, 84th, 98th, 105th and 113rd day of gestation as well as 17 lactating sows on the 26th day of lactation. The animal bodies of pregnant sows were divided in 15 fractions and those of non-pregnant and lactating sows in 12 fractions. The investigations were carried out with 3 x 3 variants of litter number (1, 2, 4) and energy supply (120, 100, 80% of requirement recommendation). The chemical composition and the energy content of the animal body fractions as well as their relative portions of the empty body were largely constant during the course of gestation with the exception of the reproductive organs and the conception products. The physiological stage of lactation connected with limited mobilization of body reserves resulted in a reduction in fat content of some body fractions as well as a limited increase of the portions of body organs contrary to the portions of body tissues of the empty body. In comparison with sows of litter numbers 1 and 2 the sows of litter number 4 were characterized by higher portions of bones and meat, valuable parts as well as by smaller portions of depotfat and meat from head and belly of empty body. The raising of the energy supply of the pregnant sows increased the portion of the depotfat and decreased the portion of the meat, valuable parts of the empty body. The chemical composition of the reproductive organs and the conception products as well as the portions of these fractions of the empty body were influenced strongly from the course of the gestation and lactation resp. The portions of the reproductive organs and of the conception products are small (related to energy < or = 5.7 and < or = 2.6% resp.)

[The effect of the phosphorus supply on the energy metabolism of growing swine]. / Untersuchungen zum Einfluss der Phosphor-Versorgung auf den Energieumsatz wachsender Schweine.

In growing barrows (live weight 17-30 kg) 3 g P/kg DM feed resulted in comparison to 6 g P/kg DM in 8% lower live weight gain. The lower live weight gain had no relation to N- and energy retention. The lower P feeding has only low effect on energy excretion in faeces and urine (1% of gross energy). A submarginal P feeding has no influence on N- and energy metabolism of growing pigs.

[The energy and nitrogen metabolism of pregnant and lactating sows and suckling piglets. 1. Experimental plan and results concerning the live weight development of pregnant, non-pregnant and lactating sows and the reproductive performance during gestation and lactation]. / Untersuchungen zum Energie- und Stickstoffumsatz von graviden und laktierenden Sauen sowie von Saugferkeln. 1. Mitteilung--Versuchsplan und Ergebnisse zur Lebendmasseentwicklung von graviden, güsten und laktierenden Sauen sowie zu Reproduktionsleistungen in Gravidität und Laktation.

The aim of the experiments was to work out new results for a factorial derivation of energy and protein requirement. The experiments were carried out according to a 3 x 3 factorial experimental plan with 3 variants of litter number (1, 2 and 4, age of sows) and 3 variants of energy supply (120, 100 and 80% of the norm of pregnancy, continued in lactation with 80, 100 and 120%). Methods of the indirect calorimetry and the slaughtering technique were used. The mean cumulative live weight changes of the sows for the 9 experimental variants amounted from 13.1 to 63.2 kg for the 115 days of pregnancy and from -17.0 to 6.8 kg for the first 26 days of lactation. The chosen variation of energy supply of pregnant and lactating sows had no relevant effect on the reproductive performances, measured by litter size, weight of conception products, litter weight at birth and the quantity of milk per sow and day respectively. In comparison with the sows of litter number 1 the sows of litter number 2 and 4 had higher litter weights at birth and higher milk quantities.

[The energy and nitrogen metabolism of pregnant and lactating sows and suckling piglets. 2. Chemical composition and energy content of the animal bodies of pregnant, non-pregnant and lactating sows]. / Untersuchungen zum Energie- und Stickstoffumsatz von graviden und laktierenden Sauen sowie von Saugferkeln. 2. Mitteilung--Chemische Zusammensetzung und Energiegehalt der Tierkörper von graviden, güsten und laktierenden Sauen.

The influence of litter number (1, 2 and 4, age of sows) as well as gestation and lactation stage of sows on the chemical composition and on the quantities of protein and fat of their bodies was investigated. The slaughter of 46 pregnant, 18 non-pregnant and 17 lactating sows were carried out at the 1st, 56th, 84th, 98th, 105th and 113th day of gestation, 113th day of experiment (non-pregnant sows) and 26th day of lactation. The results were related to the sows' energy supply (120, 100 and 80%) with equal supply of protein, vitamins and minerals. Within the tested litter numbers the chemical composition of the bodies was nearly constant during the whole time of gestation and lactation. A good agreement existed for the chemical composition of the sows' bodies of litter number 1 and 2. In comparison to them the bodies of litter number 4 contained more protein and less fat per kg dry matter. The quantities of body protein and fat increased in the gestation and decreased in the lactation period, in each case the quantities of fat exceeded than the quantities of protein. The quantities of body protein increased with higher litter number. The quantities of body fat increased from litter number 1 to 2 and were nearly equal in the sows of litter numbers 1 and 4. Within one litter number the amounts of body protein and fat attained the same level in pregnant, non-pregnant and lactating sows.

[Determination of kinetic parameters of protein metabolism in growing rats in conjunction with measurement of energy metabolism. 1. Determination of kinetic parameters of protein metabolism in relation to body weight and protein content of the feed]. / Bestimmung von kinetischen Parametern des Proteinmetabolismus bei wachsenden Ratten in Verbindung mit Energieumsatzmessungen. 1. Mitteilung. Bestimmung von kinetischen Parametern des Proteinmetabolismus in Abhängigkeit von der Lebendmasse und dem Proteingehalt des Futters.

The digestibility, the N balance, the rate of protein synthesis and other parameters, characterising the protein metabolism in dependence on live weight, protein- and energy supply are estimated on Wistar rats (4-5 animals/group). These experiments were done in 5 alternating consecutive growth and energy maintenance periods at 4 different levels of protein (6, 10, 17, 26% CP) during the live weight period of 70 to 230 g. The rate of protein synthesis was calculated from the course of renale 15N excretion by means of the end product method after giving a single dose of a mixture of 17 15N labelled amino acids. N deposition, rate of protein synthesis and flux rate increased with the protein level of the ration. During maintenance these data were much lower, but showed the same dependence on the protein level. The absolute protein synthesis (g/d) increased up to the live weight of 130... 180 g and decreased afterwards according to the age. The reutilization rate varied between 44 and 87% and decreased with increasing dietary protein level by 27% and during proceeding age by 8 ... 12%. In contrast to the absolute metabolism rates (g/d) the fractional rates (%/d) clearly decreased with the age of the animals. The stimulation of these rates by the dietary protein level resembled that for the absolute rates of synthesis. The protein deposition showed the typical course of a growing curve according to the N intake and the protein synthesis showed practically the same course but on a higher level. The break down remained constantly (approximately 140 mg N/d) up to an N intake of about 360 mg and afterwards it increased too.

[Determination of kinetic parameters of protein metabolism in growing rats in conjunction with the measurement of energy metabolism. 2. Determination of the energy requirement for protein retention in conjunction with measurement of the protein synthesis rate at different levels of protein supply]. / Bestimmung von kinetischen Parametern des Proteinmetabolismus bei wachsenden Ratten in Verbindung mit Energieumsatzmessungen. 2. Mitteilung. Bestimmung des Energiebedarfs für den Proteinansatz in Verbindung mit Messungen der Proteinsyntheserate auf unterschiedlichen Niveaus der Proteinversorgung.

Energy metabolism-by means of indirect calorimetry-and kinetic parameters of the protein metabolism on the basis of the 3-compartment model were measured with 4 groups of 4 or 5 male Wistar rats in the growth range of between 70 and 230 g live weight in a total of 5 alternately successive periods at the feeding levels growth and energy maintenance as well as 4 different levels of protein supply (6, 10, 17 and 26% crude protein in the feed). The partial energy requirement values for protein retention (bp) for every animal and every period are calculated from the data of energy metabolism. On an average of the 3 growth periods they amounted to 1.75 +/- 0.37 kJ/kJ. A statistically significant linear relation with a slope of approximately 1 could be derived regressively between the protein synthesis rate and the protein retention rate, including all 5 test periods. There was no proven relation between the bp values and the corresponding individual values of the ratio of protein synthesis rate-diminished by the regressively derived protein synthesis rate in the N balance-to the protein retention rate. The results do not permit proven statements on the quantitative relations between protein turnover and energy requirement for protein retention, which is first of all due to methodical shortcomings in measuring both protein metabolism and energy metabolism. They indicate, however, that the heat production from protein synthesis has only a relatively low share in the additional energy expenditure for protein retention and does not considerably surpass the necessary minimal cost for the synthesis of the deposited protein in growing rats.

[The energy metabolism of growing swine in the liveweight range of 10-50 kg. I. Study design, feed intake and digestibility]. / Untersuchungen zum Energieumsatz wachsender Schweine im Lebendmassebereich von 10-50 kg. 1. Mitteilung. Versuchsanlage, Futteraufnahme und Verdaulichkeit.

Studies of the energy metabolism at maintenance and growth levels after the feeding of rations with a crude protein content of 17-24% and 44-47% resp. were carried out with hybrid pigs of line 150 in the live weight range between 10 and approximately 50 kg. This paper gives information on the methods and the outlay of the experiment and presents results concerning feed intake, live weight development and digestibility. Feed intake increased on average with growing live weight by 30-35 g DM/kg live weight. Feed conversion ranged from 1.2 to 1.8 kg DM/kg live weight gain in the first period and from 2.3 to 3.2 kg DM/kg live weight gain in the last period. The digestibility of the energy in the rations with a crude protein content of between 17 and 24% averaged 80% and that of the rations with a crude protein content of 44-47% averaged 86%. In the course of ontogenetic development the digestibility increased up to about 30 kg LW. The influence of the nutritional level on the level of digestibility was unequal in the experiments. In one experiment a decrease (1% unit) and in two experiments an increase (1-3% units) of the digestibility after the feeding of growth level in contrast to maintenance level could be observed. The change of rations with a varying protein content did not result in an influence on the digestibility level in comparison with the constant feeding of one ration.

[The energy utilization of alfalfa leaf by adult swine]. / Zur energetischen Verwertung von Luzerneblatt durch adulte Schweine.

By means of the respiration test technique the energy metabolism of adult pigs fed with a basic ration plus alfalfa leaves with 110-200 g crude fibre/kg DM was measured in 3 test periods. The digestibility of the energy of the alfalfa leave ranks amounted to--decreasing with increasing crude fibre content--66, 60 and 59%; the respective energy retention values were 7.5, 6.9 and 6.9 MJ NEFs or 510, 470 and 470 EFs/kg DM. According to the measured values there were no significant differences in the digestibility of the energy and in the energy concentration of NEFs between fresh and dried alfalfa leaves of largely equal chemical composition.

[The energetic utilization of rations with dried concentrates, potatoes, sugar beets, apple pectin and cane sugar by growing, intact and ileorectostomized swine. 1. Results in swine with ileorectal anastomoses]. / Untersuchungen zur energetischen Verwertung von Rationen mit Trockenkonzentraten, Kartoffeln, Zuckerrüben, Apfelpektin und Rohrzucker durch wachsende, intakte und ileorektostomierte Schweine. 1. Mitteilung. Ergebnisse an Schweinen mit Ileo-Rektal Anastomosen.

Rations with dried feedstuffs and rations with between 30 and 50% raw potatoes in the dry matter as well as steamed potatoes and sugar beets, sucrose and apple pectin were tested in measurings of the total metabolism in growing pigs with ileo-rectal anastomoses. The prececal digestibility of the energy of the rations ranged between 42% (rations with raw potatoes) and 79% (rations with sucrose). The digestibility of the rations with a 50% quota of steamed potatoes was better by 30%--units than that of rations with raw potatoes. In addition to crude nutrient digestibility, data are given on the digestibility of starch, water soluble carbohydrates and pectin. The wide variation in the N retention of 6-25 g/animal.day can only be partly connected with energy retention. Urine energy amounted to between 2.5 and 5% of gross energy. The average utilization of metabolizable energy amounted to 69.4%. A connection is to be seen with the value of energy maintenance requirement of 646 kJ retention energy/kg LW0.62.d.

[Energy metabolism of growing broilers in relation to the environmental temperature]. / Energieumsatz wachsender Broiler in Abhängigkeit von der Umgebungstemperatur.

7 experiments with 6 chickens each (origin Tetra B) in the live weight range between greater than 100 and less than 300 g and up to 1800 g were carried out at environmental temperatures (ET) of 35, 30, 25 (2 experiments) 20 (2 experiments) and 15 degrees C. In the course of each experiment the chickens alternatively received feed mixtures containing 20 and 40% crude protein (3 animals/variant) for maintenance and weight gain (semi ad libitum). Energy metabolism was measured according to indirect calorimetry over a total of 645 metabolism periods. In the temperature range studied there was no compensation between thermoregulatory heat and heat from other metabolic processes. The partial utilization of metabolizable energy for energy retention in the body was independent of ET and remained in the limits between 71 and 73%. Energy utilization was dependent on the protein content of the feed. It decreased from 75 to 69% with the increase of the protein content from 20 to 40%. Energy requirement for protein retention varied between 1.67 and 1.89 kJ metabolizable energy/kJ and was independent of ET. Energy requirement (metabolizable energy) for the maintenance of the energy balance was independent of the protein content of the feed. It increased from 433 kJ/kg LW0.75.d at 35 degrees C to 693 kJ/kg LW0.75.d at 15 degrees C ET. The relationship between heat production and ET is parabolic. The thermoneutral temperature decreased from 35 to 25 degrees C in the course of development. In the live weight range of 300-500 g thermoregulatory heat production had its maximum with 19 kJ/kg LW0.75.d.K and decreased in the further development to 10-13 kJ/kg LW0.75.d.K.

[Energy metabolism of growing rats in relation to the environmental temperature]. / Energieumsatz wachsender Ratten in Abhängigkeit von der Umgebungstemperatur.

8 experiments were carried out with 9 albino rats each (Wistar line, bred at the institute) in the live weight range between 70 and 200 g and at environmental temperatures (ET) of 34, 32, 30, 28, 26, 24, 22 and 20 degrees C. In the course of each individual experiment the rats were alternatively fed for maintenance and weight gain (semi ad libitum) with feed mixtures containing 10, 25 and 40% crude protein (3 animals/variant). Energy metabolism was measured according to the method of indirect calorimetry over a total of 780 metabolism periods. In the temperature range studied there was no compensation between thermoregulatory heat and heat from other processes of the metabolism. The partial utilization of metabolizable energy for energy retention in the body was independent of ET and ranged between 73 and 80% for the 7 experiments with ET between 32 and 20 degrees C. Energy utilization depended on the protein content of the feed and decreased from 81 to 79 or 73 resp. when the protein content increased from 10 to 25% or to 40% resp. Energy requirement for protein retention varied between 1.61 and 2.09 kJ metabolizable energy/kJ and was independent of ET. Energy maintenance requirement (measured at 28, 30 and 32 degrees C) increased with the growing protein content from 415 to 439 and 447 kJ/kg LW0.75.d resp. (regression analysis) and from 411 to 420 and 432 kJ/kg LW0.75.d (measuring at maintenance level). The relative weight gain with the increased protein content of the feed largely corresponds to the expected values according to the efficiency of ATP synthesis in the oxidative degradation of nutrients. The relationship between heat production and ET is parabolic. In the live weight range studied the average thermoneutral temperature (TNT) was 32 degrees C. It decreased during the course of development from 34 to 30 degrees C. TNT decreased with the growing protein content of the feed. Thermoregulatory heat production depended on both environmental temperature and the stage of development. Its average value in the development range studied decreased with an increase of the environmental temperature by 2 K each, starting from 20 degrees C and rising to 32 degrees C, in the following linear sequence: 23.3, 21.0, 16.8, 12.5, 8.3, 4.0 and 0.3 kJ/kg LW0.75.d.K.

[The energetic utilization of sugar beets, dried chips, cane sugar and apple pectin by growing swine. 2. Nitrogen and energy metabolism]. / Untersuchungen zur energetischen Verwertung von Zucker-rüben, Trockenschnitzeln, Rohrzucker und Apfelpektin durch wachsende Schweine. 2. Mitteilung. Stickstoff- und Energieumsatz.

The energetic utilization of rations with raw and steamed sugar beets, dried sugar beet pulp (16 measured values each), sucrose and apple pectin (8 measured values each) as supplement feed to a basic ration was measured at 4 growing pigs each in the live weight range of between 40 and 130 kg. The utilization of the energy in the rations amounted to 69.1 +/- 5.5, 68.3 +/- 7.1, 60.9 +/- 5.8, 70.5 +/- 4.1 and 69.9 +/- 6.9% (same sequence as above). The utilization values for the supplemented feedstuffs were 69.2 +/- 7.4, 68.0 +/- 10.0, 55.9 +/- 9.7, 72.2 +/- 7.6 and 71.7 +/- 17.3%. The average retention value of the digestible pectin was derived from the test results with dried sugar beet pulp and apple pectin as 5.8 kJ/g. An influence of the ontogenetic development on energy utilization cannot be derived from the comparison of the retention effect of digestible nutrients measured at growing pigs and that derived from adult pigs.

[Effect of the nutrition level and sex on the energy maintenance requirement of broilers and rats]. / Einfluss von Ernährungsniveau und Geschlecht auf den Energieerhaltungsbedarf von Broilern und Ratten.

In 3 experiments young broiler chickens were supplied on various feeding levels in the growth range between 200 and 2500 g live weight (2.8 and 2.0 in experiment 1, 2.8, 2.3 and 1.8 in experiments 2 and 4, maintenance = feeding level 1.0). In experiments 1 and 2 short-time measurings (30 min) of heat production by means of gas exchange were made at 500, 1000, 1500 and 2000 g live weight in the post-absorptive state and on the maintenance level of feeding. In experiment 1 the heat production of the restrictively fed chickens was in 3 out of the 4 stages of development studied significantly lower by 10-14% than that of the intensively fed ones. In experiment 2 such an effect could not be observed. Fed on the level of energy maintenance, broilers weighing approximately 2000 g (experiment 3) did not show a significant influence of the sex on heat production as a result of 30-minute gas exchange measurings in the post-absorptive state. In experiment 4 24-hour measurings of the energy metabolism were carried out in the growth development in periods of feeding on the maintenance level by means of indirect calorimetry. In the live weight range between 0.9 and 1.3 kg there was only a low, non-significant decrease of the energy maintenance requirement of 4-6% of the highly restrictively fed chickens in comparison to the intensively fed ones. After continued feed restriction (live weight range 1.7-2.2 kg) an energy maintenance requirement reduced by 17% was measured. In an analogously arranged experiment with 24-hour energy metabolism measurings (experiment 5) male Wistar rats in the growth range between 70 and 280 g were supplied on the feeding levels 1.8 and 1.4 resp. In all three periods studied on the feeding level maintenance--beginning at 140-150 g live weight--the highly restrictively fed animals showed a slightly reduced energy maintenance requirement by 8%, 3% (non-significant) and 6% in comparison with the intensively fed animals.

[The effect of the protein level of feed on the energy maintenance requirement of rats during the course of growth and after the conclusion of the intensive growth phase using different feeding regimens]. / Der Einfluss des Proteinniveaus der Nahrung auf den Energie-erhaltungsbedarf von Ratten im Verlauf des Wachstums und nach Abschluss der intensiven Wachstumsphase bei unterschiedlichem Fütterungsregime.

In two experiments with male Wistar rats energy metabolism was measured on the feeding level of maintenance in the course of growth and in various adult periods after the application of feed mixtures with various protein-carbohydrate quotas (10, 40 and 70% crude protein) according to two different feeding regimes. While there was a change of protein levels between the animal groups in periods 1 to 3 and 8 to 10 from one period to the other, the protein levels in periods 4 to 7 and 11 to 13 remained the same for each animal group. Irrespective of the feeding regime, a dependence of the energy maintenance requirement on the nutrients according to the expected values was measured, which result from the different efficiency of ATP synthesis in the oxidative degradation of the nutrients. On an average of the periods maintenance requirement amounted to 357 +/- 21, 399 +/- 16 and 443 +/- 28 kJ/kg LW0.75.d (experiment 1) and 350 +/- 29, 383 +/- 34 and 442 +/- 30 kJ/kg LW0.75.d (experiment 2) for 10, 40 and 70% crude protein in the feed. The relation between the maintenance requirement values was 100:112:124 and 100:109:126. This contrasts with the relative expected values of 100:108:115 and 100:109:116.