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1.
J Nurses Staff Dev ; 15(5): 198-204, 1999.
Article in English | MEDLINE | ID: mdl-10776133

ABSTRACT

Decentralization, cost containment, and downsizing continue in full force as healthcare organizations continue to adapt to constant economic change. Hospitals are forced to take a second and third look at how health care is managed in order to survive. Six Northwest Florida hospitals were surveyed in an effort to explore current changes within the healthcare delivery system. This article provides both managers and staff with an overview of recent healthcare changes in an area of the country with implications for staff development.


Subject(s)
Attitude of Health Personnel , Decision Making, Organizational , Hospital Costs/organization & administration , Hospital Restructuring/organization & administration , Nurse Administrators/psychology , Personnel Downsizing/organization & administration , Cost Control , Florida , Humans , Needs Assessment , Nurse Administrators/organization & administration , Nursing Staff, Hospital/education , Nursing Staff, Hospital/organization & administration , Nursing Staff, Hospital/psychology , Organizational Innovation , Staff Development , Surveys and Questionnaires
2.
J Exp Med ; 144(1): 241-58, 1976 Jul 01.
Article in English | MEDLINE | ID: mdl-1084405

ABSTRACT

The ability of small numbers of LN cells to produce cytotoxic lymphocytes on in vitro culture with allogeneic stimulator cells is greatly augmented by the addition of spleen cells from athymic nude mice. The possibility that the synergism is a result of improved culture conditions or a "feeder effect" is excluded. All cytotoxic cells found in these cultures are shown to be T cells and to arise from precursors contained in the LN-cell component. The nude spleen cell component appears to be providing a required non-T cell which has been lost from the LN component through dilution. Synergism between the two components can occur whether they are syngeneic or allogeneic provided that both can recognize the same alloantigens in the stimulator population.


Subject(s)
Immunity, Cellular , Lymphocytes/immunology , Animals , Cytotoxicity Tests, Immunologic , Genes , Histocompatibility Antigens , Isoantigens , Mice , Mice, Inbred Strains , Mice, Nude , Spleen/immunology , T-Lymphocytes/immunology
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