Intraoral lesions associated with sebaceous nevus syndrome.

The sebaceous nevus syndrome describes the rare association of a sebaceous nevus with systemic features such as mental retardation, seizures and colobomas (among others). It is thought to be a cutaneous mosaic inherited as a paradominant trait. Three cases are provided illustrating the intraoral manifestations of the syndrome. The first histological comparison of contiguous mucosal and cutaneous lesions is provided. We also describe the possible association of SFM syndrome with a benign fibrous histiocytic lesion of the mandible. This and other mandibular tumors associated with the sebaceous nevus syndrome may have significant implications for patients. Awareness of the potential presence or development of significant intraoral lesions in association with the sebaceous nevus syndrome is important for those involved in the care of patients with this syndrome.

The sebaceous nevus as part of the Schimmelpenning-Feuerstein-Mims Syndrome--an obvious phacomatosis first documented in 1927.

The sebaceous nevus is a common nevus and can be easily diagnosed because of its typical rough fatty surface due to its amount of sebaceous glands. In some rare cases, the sebaceous nevus is part of a genetic disorder, the Schimmelpenning-Feuerstein-Mims (SFM) syndrome. If the SFM syndrome is suspected, further investigation is necessary, because multiple organ involvement is highly likely. We suggest that diagnosis of the SFM syndrome is simple, considering the special linear arrangement of sebaceous nevi in cases of SFM syndrome.

[Long-term observation of a case of organoid naevus phakomatosis (Schimmelpenning-Feuerstein-Mims syndrome)]. / Langjährige Verlaufsuntersuchung einer organoiden Nävusphakomatose (Schimmelpenning-Feuerstein-Mims-Syndrom).

The course of an organoid naevus phakomatosis (Schimmelpenning-Feuerstein-Mims syndrome) was observed in one patient over 25 years. Although the syndrome was fully developed, it has so far remained relatively benign, without limiting the patient's ability to work. During the course of the disease various investigations were carried out (CT, brain scintigrams, chromosome analysis). These confirm that the outstanding feature consisting of fibrous bone dysplasia of the skull continues to progress into adult life. In addition, the presence of intracerebral calcification could be demonstrated. Examination of the chromosomes suggests that further similar cases should also be examined, since the aetiology and pathogenesis of this phakomatosis are still unknown.

[Taking offense and illness - the pathology of interaction as seen by a psychiatrist (author's transl)]. / "Kränkung und Krankheit" - Die Pathologie der Interaktion aus der Sicht der Psychiatrie

Theories of interaction matter not only for psychoreactive disturbances, pathologic forms and sequelae of interaction may influence or even determine origin and course of psychoses. Present treatment or schizophrenic problems contains the danger that psychogenetic theories are sharply confronted with biologic concepts. As fas as we know today both are equally ligitimate. Purely psychogenetic theories like that of Bateson do not always avoid the temptation to ask and answer questions of guilt. This is therapeutically nearly always useless and may lead to arrogance. Psychotherapy of endogenous psychoses - up to now mostly only a demand - cannot be realized by adopting a model theory. It is more a question of the attitude of the physician.