ABSTRACT
Twenty-nine patients with a thyroid carcinoma invading the larynx and trachea were treated over a 25-yr period. Eight patients had invasion of the walls of the trachea or larynx and 21 had invasion into the lumen. Of the 15 patients who underwent limited surgery, i.e. total thyroidectomy, tracheostomy and neck dissection, 8 had intraluminal invasion and 7 suffered from bleeding into the trachea or airway obstruction. In contrast, none of the 13 who underwent extensive surgery, i.e. thyroidectomy, laryngectomy, partial resection of the trachea and one resection of the pharynx, (12 of whom had intraluminal invasion) showed either bleeding into the trachea or airway obstruction. Although the prognosis was no better in the group undergoing extensive operation there is the feeling that in cases with intraluminal invasion extensive surgery is indicated to prevent the severe airway difficulties which often develop in such patients.
Subject(s)
Laryngeal Neoplasms/pathology , Thyroid Neoplasms/pathology , Tracheal Neoplasms/pathology , Adult , Aged , Child , Female , Humans , Laryngeal Neoplasms/surgery , Male , Methods , Middle Aged , Neoplasm Invasiveness , Thyroid Neoplasms/surgery , Tracheal Neoplasms/surgeryABSTRACT
Bilateral involvement of the temporal bones is a rare manifestation of eosinophilic granuloma, a disease characterized by solitary or multiple foci of osteolytic damage. We report two cases in which the ambiguous and unusual initial symptoms and clinical course constituted a difficult diagnostic problem. In each case, the therapeutic approach used was different: the first was treated with a combination of radiotherapy and corticosteroids and the second with a combination of chemotherapy and corticosteroids. We have reviewed the literature, and the possible symptoms and clinical course are described. We report our views on the diagnostic and therapeutic aspects of the disease.
Subject(s)
Eosinophilic Granuloma/diagnosis , Hearing Loss, Bilateral/etiology , Hearing Loss/etiology , Temporal Bone , Child , Child, Preschool , Eosinophilic Granuloma/therapy , Female , HumansABSTRACT
A review of the literature on tumors of the small salivary and mucous glands reveals that mucoepidermoid carcinoma of the upper respiratory system is a very rare occurrence. Three such cases are reported in detail, representing 3% of all tumors of small salivary and mucous gland origin recorded by the authors over a period of 20 years. This incidence is high. Follow-up was from 3 to 12 1/2 years.
