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Tumori ; 104(6): 466-470, 2018 Dec.
Article in English | MEDLINE | ID: mdl-28315510

ABSTRACT

PURPOSE: To assess the contribution of Italian radiation oncologists in the current management of recurrent high-grade gliomas (HGG), focusing on a reirradiation (reRT) approach. METHODS: In 2015, the Reirradiation and the Central Nervous System Study Groups on behalf of the Italian Association of Radiation Oncology (AIRO) proposed a survey. All Italian radiation oncologists were individually invited to complete an online questionnaire regarding their clinical management of recurrent HGG, focusing on a reRT approach. RESULTS: A total of 37 of 210 questionnaires were returned (18% of all centers): 16 (43%) from nonacademic hospitals, 14 (38%) from academic hospitals, 5 (13%) from private institutions, and 2 (6%) from hadron therapy centers. The majority of responding centers (59%) treated ≤5 cases per year. Performance status at the time of recurrence, along with a target diameter <5 cm and an interval from primary radiation ≥6 months, were the prevalent predictive factors considered for reRT. Sixty percent of reirradiated patients had already received a salvage therapy, either chemotherapy (40%) or reoperation (20%). The most common approach for reRT was fractionated stereotactic radiotherapy to a mean (photon) dose of 41.6 Gy. CONCLUSIONS: Although there were wide variations in the clinical practice of reRT across the 37 centers, the core activities were reasonably consistent. These findings provide a basis for encouraging a national collaborative study to develop, implement, and monitor the use of reRT in this challenging clinical setting.


Subject(s)
Glioma/radiotherapy , Neoplasm Recurrence, Local/radiotherapy , Radiation Oncologists/statistics & numerical data , Re-Irradiation/statistics & numerical data , Re-Irradiation/standards , Adolescent , Combined Modality Therapy/standards , Combined Modality Therapy/statistics & numerical data , Female , Humans , Italy , Male , Salvage Therapy/standards , Salvage Therapy/statistics & numerical data , Surveys and Questionnaires
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