1.
J Acquir Immune Defic Syndr
; 78(4): e28-e30, 2018 08 01.
Article
in English
| MEDLINE
| ID: mdl-29672350
Subject(s)
Disease Transmission, Infectious/prevention & control , HIV Infections/prevention & control , Health Knowledge, Attitudes, Practice , Patient Acceptance of Health Care , Pre-Exposure Prophylaxis/methods , Adolescent , Adult , Aged , Aged, 80 and over , Chemoprevention/methods , Facilities and Services Utilization , Female , Humans , Male , Middle Aged , Young Adult
2.
3.
Int J Epidemiol
; 46(3): 790-791g, 2017 06 01.
Article
in English
| MEDLINE
| ID: mdl-27272185
Subject(s)
Anti-HIV Agents/therapeutic use , HIV Infections/drug therapy , HIV-1/genetics , Veterans Health , Veterans/statistics & numerical data , Adult , Aged , Antiretroviral Therapy, Highly Active , Cohort Studies , Female , HIV Infections/mortality , HIV-1/immunology , Humans , Male , Middle Aged , Prospective Studies , Retrospective Studies , Treatment Outcome , United States/epidemiology
4.
Antimicrob Agents Chemother
; 49(9): 3930-2, 2005 Sep.
Article
in English
| MEDLINE
| ID: mdl-16127074
ABSTRACT
Serial passage of human immunodeficiency virus type 1 in MT-2 cells in increasing concentrations of the d- and l-enantiomers of beta-2',3'-didehydro-2',3'-dideoxy-5-fluorocytidine (d4FC) resulted in the selection of viral variants with reverse transcriptase substitutions M184I or M184V for l-d4FC and I63L, K65R, K70N, K70E, or R172K for d-d4FC. Phenotypic analysis of site-directed mutants defined the role of these mutations in reducing susceptibility to l- or d-d4FC.
