Subject(s)
Antineoplastic Agents/administration & dosage , Imidazoles/administration & dosage , Leukemia, Myelogenous, Chronic, BCR-ABL Positive/therapy , Precursor Cell Lymphoblastic Leukemia-Lymphoma/therapy , Pyridazines/administration & dosage , Stem Cell Transplantation , Adult , Allografts , Female , Humans , Middle Aged , RecurrenceABSTRACT
In the forensic literature only a few scientific reports are dealing with series of histopathological bone marrow (BM) investigations, mainly concerning changes after drug abuse and alcoholic consumption. In a period of 13 years (1995-2008) we routinely investigated 225 BM specimens from anterior iliac crests taken at forensic autopsies if the cause of death was unclear or vague, septicaemia was suspected or known, in cases of presumed haemorrhagic diathesis or bleeding tendencies, spleens were found to be enlarged or intoxications were suspected or proofed. In 78 cases (34.66%) abnormal histopathologic changes were found. Forty of those revealed neoplastic, mainly haematological diseases, which were unknown during lifetime. Referring to our findings, extraction of post-mortem BM specimens for histopathological investigations should become an essential issue for both the forensic and clinical pathologist.
Subject(s)
Bone Marrow/pathology , Hematologic Diseases/pathology , Adolescent , Adult , Aged , Aged, 80 and over , Biopsy , Child , Child, Preschool , Female , Forensic Pathology , Humans , Ilium/pathology , Immunohistochemistry , Infant , Infant, Newborn , Male , Mast Cells/pathology , Megakaryocytes/pathology , Middle Aged , Plasma Cells/pathology , Sepsis/pathology , Young AdultABSTRACT
We present a compact source of polarization-entangled photon pairs at a wavelength of 805 nm using a violet single-mode laser diode as the pump source of type-II spontaneous parametric down-conversion. The source exhibits entanglement and pair-rate comparable to conventional systems utilizing large frame ion lasers thus significantly increases the practicality of novel quantum information or quantum metrology applications.
ABSTRACT
An 85-year-old patient suffered from progressive deterioration (NYHA III) for several months. Cardiac disease was suspected. Echocardiography as well as a CT scan of the heart revealed a heart tumor to be the cause. Tumor staging was negative. After transvenous biopsy, the diagnosis of a Burkitt lymphoma could be established. Due to the advanced age of the patient, the intended surgical therapy was turned down and the patient was treated with 6 courses of a potentially therapeutic chemotherapy (CHOP scheme), which was well tolerated by the patient. The following CT scan showed a complete remission of the tumor. Six months after chemotherapy the patient is in NYHA stage I.
Subject(s)
Burkitt Lymphoma/diagnostic imaging , Heart Atria/diagnostic imaging , Heart Neoplasms/diagnostic imaging , Aged , Aged, 80 and over , Antineoplastic Combined Chemotherapy Protocols/administration & dosage , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Burkitt Lymphoma/drug therapy , Burkitt Lymphoma/pathology , Burkitt Lymphoma/surgery , Chemotherapy, Adjuvant , Cyclophosphamide/administration & dosage , Diagnosis, Differential , Doxorubicin/administration & dosage , Heart Atria/pathology , Heart Atria/surgery , Heart Neoplasms/drug therapy , Heart Neoplasms/pathology , Heart Neoplasms/surgery , Humans , Male , Prednisone/administration & dosage , Tomography, X-Ray Computed , Vincristine/administration & dosageABSTRACT
An 85-year-old patient suffered from progressive deterioration (NYHA III) for several months. Cardiac disease was suspected. Echocardiography as well as a CT scan of the heart revealed a heart tumor to be the cause. Tumor staging was negative. After transvenous biopsy, the diagnosis of a Burkitt lymphoma could be established. Due to the advanced age of the patient, the intented surgical therapy was turned down and the patient was treated with 6 courses of a potentially therapeutic chemotherapy (CHOP scheme), which was well tolerated by the patient. The following CT scan showed a complete remission of the tumor. Six months after chemotherapy the patient is in NYHA stage I.
