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Chem Commun (Camb)
; 47(28): 8007-9, 2011 Jul 28.
Article
in English
| MEDLINE
| ID: mdl-21670803
ABSTRACT
Using circular dichroism spectroscopy, we show evidence of unusual folding behaviour for several designed peptides in neat ionic liquid. Helical peptides, AKA(2) and Trp-cage, exhibit heat-induced folding, with stable helical structure persisting to 96 °C, whereas the ß-hairpin Trpzip4 is destabilized by the neat [C(4)mpy][Tf(2)N].
