ABSTRACT
O presente relato refere-se à experiência de estágio realizada em um Centro de Referência Especializado em Assistência Social da Grande Florianópolis, com um grupo de adolescentes em cumprimento de Medida Socioeducativa de Liberdade Assistida. Para o desenvolvimento do trabalho, objetivou-se a reestruturação das potencialidades dos adolescentes, a discussão de questões relacionadas à descrença quanto às possibilidades de reinserção social e a promoção de estratégias para o reconhecimento de possibilidades na vida dos sujeitos. Como metodologia, foram utilizadas oficinas temáticas com assuntos relevantes no contexto cultural e social dos adolescentes. Os encontros permitiram pensar a Medida Socioeducativa de Liberdade Assistida em outra perspectiva, destacando a importância de um ambiente de socialização. Os resultados apontaram uma mudança de comportamento dos jovens, maior capacidade de se comunicarem e de expressarem suas emoções.
This article refers to the training experience in the Specialized Reference Center for Social Assistance in the Great Florianópolis with a group of adolescents in compliance with d Socio-educational Measure of Assisted Freedom. For developing the work, it was objectified restructuring the potential of teenagers, discussing issues related to the disbelief of the possibilities of social reintegration, and promoting strategies with them to recognize the possibilities in their lives. The methodology used was to hold thematic workshops on topics identified as relevant to the cultural and social context of those teenagers. These meetings allowed thinking the Socio-educational Measure of Assisted Freedom with another perspective, as an effective socialization environment. The results pointed a change in behavior of the teenagers, an improvement of their communication skills, and a better expression of their emotions.
Este artículo se refiere a la experiencia en un Centro de Referencia Especializado para la Asistencia Social en la Grande Florianópolis con un grupo de adolescentes en cumplimiento de Medida Socioeducativa de Libertad Asistida. Para el desarrollo del trabajo, fue objetivada la reestructuración del potencial de los adolescentes, la discusión de temas relacionados con la incredulidad acerca de las posibilidades de reinserción social y la promoción de estrategias para el reconocimiento de las posibilidades en la vida de los individuos. La metodología utilizada fue la realización de talleres temáticos sobre temas identificados como relevantes para el contexto cultural y social de los adolescentes. Las reuniones posibilitaran pensar la Medida Socioeducativa de Libertad Asistida en otra perspectiva, identificando la importancia de un ambiente de socialización. Los resultados indicaron un cambio de comportamiento de los jóvenes, mayor capacidad de comunicación y expresión de emociones.
Subject(s)
Adolescent , Crime , Psychology, Social , Public Policy , Social WorkABSTRACT
Este estudo objetiva descrever a prevalência das hepatites B e C no município de Palhoça entre 2008 e 2012, traçar o perfil epidemiológico e diagnosticar prováveis fontes de infecção. O estudo é descritivo baseado no Sistema de Informação de Agravos de Notificação. Foram encontrados 275 casos de hepatite B e C, com prevalência variando entre 14,80 (2008) e 53,93 (2010) por 100.000 habitantes, mediana de idade de 45 anos, sendo 60% do sexo masculino e 40% do feminino, das quais 6 eram gestantes. A raça branca predominou com 91,6%; 24% dos indivíduos concluíram ensino médio; 65,9% não eram vacinados contra Hepatite B; 26,9% tinham HIV/Aids; e 5% apresentaram outra DST associada. Concluiu-se que o perfil correspondeu a homens brancos acima de 40 anos, cujas fontes de transmissão para hepatite B foram tratamento cirúrgico e uso de drogas, para a Hepatite C.
This study aimed to describe the prevalence of hepatitis B and C at Palhoça in 2008-2012, trace the epidemiological profile and diagnose probable sources of infection. The study is descriptive based on the Information System of Notifiable Diseases. There were found 275 cases of hepatitis B and C, with prevalence ranging between 14.80 (2008) and 53.93(2010) per 100.000 inhabitants, with an age median of 45 years, 60% males and 40% female, of which 6 of them were pregnant. Caucasians were predominant with 91.6%; 24%-completed high school; 65.9% were not vaccinated against hepatitis B; 26.9% had HIV/Aids; and 5% had other STD associated. Concluded that the profile corresponded to over 40-yearold, caucasians men and the most related hepatitis B transmission were the surgical treatment and hepatitis C transmission were drug use.
Subject(s)
Humans , Male , Female , Pregnancy , Child , Adolescent , Adult , Middle Aged , Young Adult , Prevalence , Hepatitis C/epidemiology , Hepatitis B/epidemiology , Epidemiology, Descriptive , Epidemiological Monitoring , Health Information SystemsABSTRACT
A hemicryptophane ligand soluble in water at neutral pH was obtained thanks to the derivatization of the cyclotribenzylene unit with three carboxylate groups. The corresponding Cu(ii) complex was then synthesized and its spectroscopic and electrochemical properties in water were investigated, showing that water solubilisation retains the geometry of the complex around the metal center but strongly affects its redox properties, compared to previously reported Cu(ii)@hemicryptophane complexes soluble in organic solvents.
ABSTRACT
Four new enantiomerically and diastereomerically pure hemicryptophane hosts (M-SSS-2/P-SSS-2 and M-RRR-2/P-RRR-2 pairs) were designed for the recognition of sugar derivatives. Their absolute configuration was determined from the circular dichroism spectra and DFT calculations. The host molecules were then used for the stereoselective recognition of glucopyranosides. Binding constants were obtained from (1)H NMR titration experiments showing an increase of affinity for this class of receptors, associated with an improved diastereo- and enantio-differentiation.
Subject(s)
Glucosides/chemistry , Polycyclic Compounds/chemistry , Circular Dichroism , Kinetics , Models, Molecular , Molecular Conformation , Proton Magnetic Resonance Spectroscopy , Quantum Theory , StereoisomerismABSTRACT
The first water-soluble hemicryptophane cage compound, 4, was synthesized in seven steps from commercially available products, and its complexation properties were studied. NMR and ITC experiments indicate that 4 is an efficient receptor for choline in water (ΔG° = -5.2 kcal mol(-1)). High substrate selectivity was achieved since no complexation was observed for its closely related substrates: glycine betaine and betaine aldehyde. Density functional theory calculations were performed to analyze the interactions that are involved in the formation of the inclusion complex.
Subject(s)
Choline/chemistry , Polycyclic Compounds/chemical synthesis , Betaine/analogs & derivatives , Betaine/chemistry , Magnetic Resonance Spectroscopy , Molecular Structure , Polycyclic Compounds/chemistry , Quantum Theory , WaterABSTRACT
The synthesis of the first members of a new class of cyclic peptide-containing hemicryptophanes is described. Synthesis was achieved through attachment of veratryl groups to the L-tyrosine side chains of a cyclic hexapeptide, c(YG)3, followed by intramolecular cyclodehydration to generate the CTV unit. The diastereomeric P- and M-hemicryptophanes were generated in a 2 : 1 ratio and were separated by chromatography. The enantioselective binding properties of the hemicryptophanes were investigated by complexation with carnitine. Both isomers were found to have significant selectivity for binding (R)-carnitine.
Subject(s)
Peptides, Cyclic/chemical synthesis , Polycyclic Compounds/chemical synthesis , Models, Molecular , Molecular Conformation , Peptides, Cyclic/chemistry , Polycyclic Compounds/chemistry , StereoisomerismABSTRACT
Enantiopure hemicryptophanes efficiently discriminate chiral ammonium neurotransmitters. The ephedrine and norephedrine molecules associate with hemicryptophane hosts to form 1:1 and 1:2 host-guest complexes. Binding constants are determined by fitting the ¹H nuclear magnetic resonance (NMR) titration curves to give ß1 and ß2 values, which are used to characterize the diastereomeric and enantiomeric discriminating potentials of the hosts.
Subject(s)
Ammonium Compounds , Neurotransmitter Agents/chemistry , Polycyclic Compounds/chemistry , Ammonium Compounds/chemistry , Ephedrine/analysis , Ephedrine/chemistry , Magnetic Resonance Spectroscopy , Models, Molecular , Molecular Structure , StereoisomerismABSTRACT
Questionnaires answered by 476 students (age 15-20 yrs) attending a local school in the neighborhood of Pedra 90 in Cuiabá -MT were analyzed in order to study the characteristics of feline and canine populations in the region. The results showed that 371 (78%) of the 476 families kept 513 dogs and 307 cats. Of 573 dogs, 289 (56.3%) were male and 224 (43.7%) were female. Of 307 cats, 182 (59.28%) were male and 125 (40.72%) were female. The owners of 474 (92.4%) dogs and 267 (86.9%) cats reported that their pets had been vaccinated against rabies.
Subject(s)
Rabies Vaccines , Rabies/veterinary , Surveys and Questionnaires , Adolescent , Adult , Animals , Castration/statistics & numerical data , Cats , Dogs , Female , Humans , Male , Rabies/prevention & control , Rural PopulationABSTRACT
Foram avaliados os questionários respondidos por 476 alunos, com idade entre 15 e 20 anos, de uma escola do bairro Pedra 90 em Cuiabá-MT, objetivando conhecer as características da populaçäo canina e felina daquele local. Dos 476 domicílios, em 371 (78 por cento), foram registrados 513 cäes e 307 gatos. Dos 513 cäes, 289 (56,3 por cento) eram machos e 224 (43,7 por cento) fêmeas. Dos 307 gatos, 182 (59,3 por cento) eram machos e 125 (40,7 por cento) fêmeas. Os proprietários de 474 (92,4 por cento) cäes e 267 (86,9 por cento) gatos afirmaram ter vacinado seus animais contra raiva
