1.
Berl Munch Tierarztl Wochenschr
; 97(10): 349-56, 1984 Oct 01.
Article
in German
| MEDLINE
| ID: mdl-6517845
Subject(s)
Antiplatyhelmintic Agents/therapeutic use , Artiodactyla , Benzimidazoles/therapeutic use , Fascioliasis/veterinary , Animals , Animals, Domestic , Animals, Wild , Antiplatyhelmintic Agents/pharmacology , Benzimidazoles/pharmacology , Fasciola hepatica/drug effects , Fascioliasis/drug therapy , Fascioliasis/parasitology , Sheep , Sheep Diseases/parasitology , Species Specificity , Triclabendazole
2.
Vet Parasitol
; 13(2): 145-50, 1983 Sep.
Article
in English
| MEDLINE
| ID: mdl-6685399
ABSTRACT
Triclabendazole (Fasinex), a new fasciolicide of the benzimidazole group, was tested in sheep and goats. A controlled test with 24 artificially-infected sheep revealed a 100% efficacy of triclabendazole at a dose of 10 mg kg-1 body weight against Fasciola hepatica aged 4 and 13 weeks, respectively. In naturally-acquired severe subacute to chronic fascioliasis in 66 sheep and 10 goats, the drug was highly effective in three trials when applied at 10 mg kg-1 in sheep and at 5 mg kg-1 in goats. Triclabendazole was well tolerated, whereas side effects occurred in one trial with niclofolan (Bilevon-M) (3 mg kg-1) which was used for comparison.