1.
Seizure
; 21(3): 227-8, 2012 Apr.
Article
in English
| MEDLINE
| ID: mdl-22265576
ABSTRACT
Minocycline, a tetracycline family antibiotic, is known to inhibit microglial activation and proinflammatory cytokine release in animal models. Experimental data show that these immune processes may play a role in epilepto- and ictogenesis. We present the case of a patient with marked reduction in seizure frequency during minocycline therapy with severe symptomatic epilepsy due to an astrocytoma.
Subject(s)
Anticonvulsants/therapeutic use , Astrocytoma/complications , Brain Neoplasms/complications , Epilepsy/drug therapy , Minocycline/therapeutic use , Astrocytoma/radiotherapy , Astrocytoma/surgery , Brain Neoplasms/radiotherapy , Brain Neoplasms/surgery , Epilepsy/etiology , Humans , Male , Melanoma/complications , Middle Aged , Neoplasms, Multiple Primary/pathology , Skin Neoplasms/complications
2.
Transplant Proc
; 22(4): 1666-70, 1990 Aug.
Article
in English
| MEDLINE
| ID: mdl-2389430