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1.
IUCrdata ; 7(Pt 10): x220947, 2022 Oct.
Article in English | MEDLINE | ID: mdl-36405850

ABSTRACT

The title compound, C35H57NO3·0.25H2O, was synthesized from de-oxy-cholic acid followed by a protection, a Mitsonobu substitution, a Staudinger reduction, formation of an amide and final reduction in the lateral chain. The compound crystallizes in the P1 space group with four steroid mol-ecules and one water mol-ecule in the triclinic cell unit. The crystal structure features O-H⋯O hydrogen bonding. The crystal studied was refined as a non-merohedral twin.

2.
Prensa méd. argent ; 103(7): 389-393, 20170000. fig
Article in Spanish | LILACS, BINACIS | ID: biblio-1372348

ABSTRACT

La trombosis auricular masiva impide el pasaje de la sangre a través del orificio mitral Un paciente de 39 años de edad, HIV positivo, con diagnóstico previo de criptococosis meníngea cumplía tratamiento antifúngico con fluconazol por vía oral, consulta por mialgias y dolor cervical. Fallece repentinamente 24 horas después de su internación. La necropsia determinó la presencia de una trombosis biauricular masiva. La criptococosis meníngea es una infección oportunista que se presenta en pacientes HIV positivos con inmunodeficiencia avanzada. Clínicamente se manifiesta por un síndrome meníngeo, por lo general incompleto, o sólo con persistencia de fiebre y cefalea, sin signos meníngeos. La letalidad de la criptococosis meníngea es elevada. La causa del fallecimiento obedece a una enfermedad no relacionada con el sida


Massive atrial thrombosis prevents passage of blood through the mitral orifice. A 39-year-old HIV-positive patient with previous diagnosis of meningeal cryptococcosis and receiving antifungal treatment with oral fluconazole, consults for myalgias and neck pain and dies suddenly 24 hours after admission. Necropsy determined the presence of massive biauricular thrombosis. Meningeal cryptococcosis is an opportunistic infection that occurs in HIV-positive patients with severe immunodeficiency. Clinically it is manifested by an incomplete meningeal syndrome, or only with persistence of fever and headache, without meningeal signs. The lethality of meningeal cryptococcosis is high. The cause of the death is due to a disease not related to AIDS


Subject(s)
Humans , Male , Adult , Autopsy , Thrombosis/complications , Acquired Immunodeficiency Syndrome/immunology , Meningitis, Cryptococcal/complications , Meningitis, Cryptococcal/mortality , AIDS-Related Opportunistic Infections/complications
3.
Neuroradiol J ; 21(6): 835-8, 2009 Jan 20.
Article in English | MEDLINE | ID: mdl-24257054

ABSTRACT

Malignant glioma is the most common primary brain neoplasm. Generally, gliomas are not included in the differential diagnosis of enhancing lesions of the central nervous system in patients infected by the human immunodeficiency virus. We report a case of gliosarcoma in a patient with AIDS presenting as a single cerebral lesion. Stereotactic brain biopsy was obtained and definitive histopathological diagnosis of gliosarcoma was made. A decline in the incidence of opportunistic infections associated with highly active antiretroviral therapy suggest the importance of early stereotactic biopsy to confirm the diagnosis of these neoplasms.

6.
Rev. argent. infectol ; 11(7): 24-6, 1998. ilus
Article in Spanish | LILACS | ID: lil-240649

ABSTRACT

El Rhodococcus es un bacilo gram+, aerobio, inmóvil, que toma la coloración ácido alcohol resistente en forma inconstante. No esporulado e intracelular, origina una zoonosis que en pacientes VIH+ provoca una infección con localización pulmonar y extrapulmonar. En el 80 por ciento de los casos la forma de presentación primaria es la neumonía cavitada. La inmunodeficiencia del huésped, la localización intracelular y un tratamiento insuficiente se relacionan con la recidiva de la infección. Se presentan 2 casos de infección por este microorganismo, en pacientes VIH+ con localización pulmonar y extrapulmonar y en uno de ellos con carácter recidivante


Subject(s)
Humans , Adult , Actinomycetales Infections/physiopathology , AIDS-Related Opportunistic Infections , Rhodococcus/drug effects , Rhodococcus/pathogenicity , Argentina
7.
Rev. argent. infectol ; 11(7): 24-6, 1998. ilus
Article in Spanish | BINACIS | ID: bin-15422

ABSTRACT

El Rhodococcus es un bacilo gram+, aerobio, inmóvil, que toma la coloración ácido alcohol resistente en forma inconstante. No esporulado e intracelular, origina una zoonosis que en pacientes VIH+ provoca una infección con localización pulmonar y extrapulmonar. En el 80 por ciento de los casos la forma de presentación primaria es la neumonía cavitada. La inmunodeficiencia del huésped, la localización intracelular y un tratamiento insuficiente se relacionan con la recidiva de la infección. Se presentan 2 casos de infección por este microorganismo, en pacientes VIH+ con localización pulmonar y extrapulmonar y en uno de ellos con carácter recidivante (AU)


Subject(s)
Humans , Adult , AIDS-Related Opportunistic Infections , Rhodococcus/pathogenicity , Rhodococcus/drug effects , Actinomycetales Infections/physiopathology , Argentina
8.
Rev. argent. infectol ; 9(1): 3-11, 1996. ilus
Article in Spanish | LILACS | ID: lil-240620

ABSTRACT

Los LNH constituyen un grupo heterogéneo de neoplasias malignas, cuyo comportamiento biológico fluctúa desde cuadros indolentes hasta neoplasias graves, con uina corta sobrevida a largo plazo. En pacientes con enfermedad debida al VIH son 60 veces más frecuentes que en la población general, con una incidencia del 2,6 por ciento. En estos enfermos, las localizaciones más frecuentes son el encéfalo, tubo digestivo, médula ósea e hígado. El compromiso cutáneo y miocárdico es poco frecuente. Se presentan dos casos de LNH en mujeres con enfermedad por el VIH-1, con localización subcutánea


Subject(s)
Humans , Female , Adult , Middle Aged , AIDS-Related Opportunistic Infections/pathology , Lymphoma, Non-Hodgkin/diagnosis , Lymphoma, Non-Hodgkin/physiopathology , Acquired Immunodeficiency Syndrome/complications , Argentina
9.
Rev. argent. infectol ; 9(1): 3-11, 1996. ilus
Article in Spanish | BINACIS | ID: bin-15451

ABSTRACT

Los LNH constituyen un grupo heterogéneo de neoplasias malignas, cuyo comportamiento biológico fluctúa desde cuadros indolentes hasta neoplasias graves, con uina corta sobrevida a largo plazo. En pacientes con enfermedad debida al VIH son 60 veces más frecuentes que en la población general, con una incidencia del 2,6 por ciento. En estos enfermos, las localizaciones más frecuentes son el encéfalo, tubo digestivo, médula ósea e hígado. El compromiso cutáneo y miocárdico es poco frecuente. Se presentan dos casos de LNH en mujeres con enfermedad por el VIH-1, con localización subcutánea (AU)


Subject(s)
Humans , Female , Adult , Middle Aged , Acquired Immunodeficiency Syndrome/complications , Lymphoma, Non-Hodgkin/diagnosis , Lymphoma, Non-Hodgkin/physiopathology , AIDS-Related Opportunistic Infections/pathology , Argentina
10.
Medicina (B Aires) ; 55(4): 337-40, 1995.
Article in Spanish | MEDLINE | ID: mdl-8728875

ABSTRACT

This paper presents the fourth case reported on the association of primary bronchial actinomycosis and foreign body. The pathogenesis of this rare association has been linked to the low respiratory tract and a foreign body (chicken bone); it depends on its characteristics and how long it has remained lodged into the bronchial tree. The diagnosis of this case was very difficult and late. Several endoscopy procedures were required in order to detect it. Our patient has been treated successfully with parenteral penicillin in association with an original bronchoscopic procedure using a laser technique to find the foreign body and take it out of the respiratory tract. We consider that it is necessary to remember this association in every patient who suffers from recurrent pneumonia, in those who are at risk of foreign body aspiration and when the presence of an endobronchial mass is suspected.


Subject(s)
Actinomycosis/etiology , Bronchi , Bronchial Diseases/microbiology , Foreign Bodies/complications , Actinomycosis/diagnosis , Actinomycosis/therapy , Adult , Aged , Bronchial Diseases/diagnostic imaging , Bronchial Diseases/pathology , Bronchial Diseases/surgery , Diagnosis, Differential , Female , Foreign Bodies/diagnosis , Foreign Bodies/surgery , Humans , Lasers , Male , Middle Aged , Radiography
11.
Medicina [B Aires] ; 55(4): 337-40, 1995.
Article in Spanish | BINACIS | ID: bin-37102

ABSTRACT

This paper presents the fourth case reported on the association of primary bronchial actinomycosis and foreign body. The pathogenesis of this rare association has been linked to the low respiratory tract and a foreign body (chicken bone); it depends on its characteristics and how long it has remained lodged into the bronchial tree. The diagnosis of this case was very difficult and late. Several endoscopy procedures were required in order to detect it. Our patient has been treated successfully with parenteral penicillin in association with an original bronchoscopic procedure using a laser technique to find the foreign body and take it out of the respiratory tract. We consider that it is necessary to remember this association in every patient who suffers from recurrent pneumonia, in those who are at risk of foreign body aspiration and when the presence of an endobronchial mass is suspected.

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