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1.
Hum Pathol ; 31(9): 1074-80, 2000 Sep.
Article in English | MEDLINE | ID: mdl-11014574

ABSTRACT

The adult rhabdomyoma is a rare, benign skeletal muscle neoplasm that usually occurs in the head and neck. A case report of an adult rhabdomyoma arising in the thigh is presented with a review of the literature. This is the first case of an extremity adult rhabdomyoma to be reported. It is also the largest at 13 centimeters. Distinction from a highly differentiated rhabdomyosarcoma is important. Recent chromosomal studies suggest that the adult rhabdomyoma is a true neoplasm. Total resection is curative but the lesion may recur if incompletely excised.


Subject(s)
Muscle Neoplasms/diagnosis , Muscle, Skeletal/pathology , Rhabdomyosarcoma/diagnosis , Aged , Aged, 80 and over , Biomarkers, Tumor/analysis , Female , Humans , Immunohistochemistry , Magnetic Resonance Imaging , Muscle Neoplasms/chemistry , Muscle Neoplasms/surgery , Muscle, Skeletal/chemistry , Muscle, Skeletal/surgery , Neoplasm Proteins/analysis , Rhabdomyosarcoma/chemistry , Rhabdomyosarcoma/surgery , Thigh/pathology , Treatment Outcome
3.
Dis Colon Rectum ; 43(5): 708-12, 2000 May.
Article in English | MEDLINE | ID: mdl-10826435

ABSTRACT

PURPOSE: Spontaneous nonocclusive ischemic colitis involving only the right colon is an infrequent occurrence. Because this problem is less recognized than its counterpart involving the left colon, the correct diagnosis may not be considered. The purpose of this article was to describe the presentation and management of this unusual clinical problem. METHODS: Five cases of nonocclusive ischemic cecal necrosis are described. Four of the patients presented with right-sided abdominal pain, tenderness, and leukocytosis. The preoperative diagnosis was incorrect in all patients, although cecal necrosis was considered in one. Two patients were thought to have. appendicitis, two were thought to have carcinoma, and one was thought to have a perforated viscus. Each patient underwent a right hemicolectomy and four survived. RESULTS: Each of the patients had ischemic cecal necrosis without evidence of emboli or vasculitis. Although cecal gangrene may occur after systemic hypotension, no such event preceded these patients' presentation. We believe that the patients we treated had a form of nonocclusive ischemic colitis, which occasionally affects only the right colon. CONCLUSION: Ischemic necrosis of the cecum is an infrequent variant of ischemic colitis that should be considered in the differential diagnosis of the elderly patient presenting with right lower quadrant pain.


Subject(s)
Cecal Diseases/surgery , Cecum/blood supply , Colitis, Ischemic/surgery , Aged , Aged, 80 and over , Cecal Diseases/diagnostic imaging , Cecal Diseases/etiology , Cecum/pathology , Colitis, Ischemic/diagnostic imaging , Colitis, Ischemic/etiology , Diagnosis, Differential , Female , Humans , Male , Middle Aged , Necrosis , Radiography
4.
Arch Surg ; 133(4): 373-6; discussion 377, 1998 Apr.
Article in English | MEDLINE | ID: mdl-9565116

ABSTRACT

OBJECTIVE: To better define the effectiveness of abdominal computed tomographic scanning (ACTS) in adult patients with suspected appendicitis. DESIGN: Retrospective analysis. SETTING: A community teaching hospital. PATIENTS: Ninety-seven patients with appendicitis in the differential diagnosis, whose clinical findings were insufficient to perform surgery or to discharge from the hospital, during a 14-month period. INTERVENTIONS: None. MAIN OUTCOME MEASURES: Accuracy of ACTS, rate of appendectomies that show no appendicitis (negative appendectomy rate), and frequency of ACTS as a definitive diagnostic test. RESULTS: Forty-nine of the 50 patients with appendicitis were correctly diagnosed by ACTS. Forty-three of the 47 patients without appendicitis were correctly diagnosed by ACTS. Positive predictive value was 92%, negative predictive value was 98%, and accuracy was 96%. The ACTS group had a negative appendectomy rate of 5.8% (3/52), lower than the hospital rate of 14% for the preceding 3 years. The ACTS established an alternative diagnosis in 16 patients, allowed 10 other patients to be discharged early or not admitted, and was the critical diagnostic test in 30 of the patients with appendicitis. Therefore, the ACTS played a definitive role in the treatment of 56 (57.7%) of the 97 patients. CONCLUSIONS: The ACTS was an accurate test in the diagnosis of appendicitis and was of significant benefit in 57.7% of the patients studied. However, it was difficult to predict which patients were most likely to benefit. Expanded selective use of ACTS for patients with clinically indeterminate appendicitis may result in a lower negative appendectomy rate and fewer patient admissions for observation.


Subject(s)
Appendicitis/diagnostic imaging , Tomography, X-Ray Computed , Acute Disease , Adult , Appendectomy/economics , Appendectomy/statistics & numerical data , Appendicitis/epidemiology , Appendicitis/surgery , Diagnosis, Differential , Female , Humans , Male , Patient Admission/statistics & numerical data , Predictive Value of Tests , Retrospective Studies , Sensitivity and Specificity , Tomography, X-Ray Computed/economics , Tomography, X-Ray Computed/statistics & numerical data
5.
Arch Surg ; 131(3): 301-8, 1996 Mar.
Article in English | MEDLINE | ID: mdl-8611096

ABSTRACT

OBJECTIVE: To describe the magnitude of changes and opportunities that may arise for simplified surgical procedures for women with breast cancer because of the decreasing size and lymph node involvement in invasive breast cancer and earlier presentation of noninvasive and invasive breast cancer. DESIGN AND MAIN OUTCOME ASSESSMENT: Cases (N=1001) of breast cancer from a tertiary and a community hospital between 1989 and 1993 were analyzed for invasion, size, nodal status, and change over time. RESULTS: Ductal carcinoma in situ constituted 14% and 18% of the cancers at the two hospitals. At the tertiary and community hospitals, the mean maximum diameters were 2.1 and 2.0 cm, respectively, and the median maximum diameters were 1.5 and 1.7 cm, respectively, for invasive breast cancer. Twenty-nine percent and 28%, respectively, were 1 cm or less in diameter. Axillary nodal metastases occurred in only 31% of the invasive cancers (tertiary hospital); only 10% had more than three nodal metastases. In the T1a and T1b cases, nodal metastases occurred in only 10% and 43% of the positive nodes were solitary; only 16% had more than three nodal metastases. The proportion of ductal carcinoma in situ, T1a and T1b, and node-negative cases increased significantly over time. CONCLUSIONS: Within the next decade, the proportion of all breast cancers that are ductal carcinoma in situ will approach 33%, and invasive cancers will approach 1 cm in median maximum diameter. Therapy simplification will be logical because of very small size, low risk of recurrence after breast conservation, and excellent prognosis, and might include increased breast conservation, avoidance of axillary nodal dissection, and omission of radiation therapy to conserve breasts. Adjuvant therapy will be based on the prognostic features of the primary cancer and findings from careful histologic examination of the sentinel lymph nodes.


Subject(s)
Breast Neoplasms/pathology , Breast Neoplasms/prevention & control , Mammography , Adult , Aged , Axilla , Breast Neoplasms/therapy , Carcinoma in Situ/prevention & control , Carcinoma in Situ/secondary , Carcinoma, Ductal, Breast/prevention & control , Carcinoma, Ductal, Breast/secondary , Female , Humans , Lymph Node Excision , Lymphatic Metastasis , Mass Screening/methods , Middle Aged , Neoplasm Invasiveness , Neoplasm Staging , Retrospective Studies
6.
Arch Surg ; 130(6): 662-5, 1995 Jun.
Article in English | MEDLINE | ID: mdl-7763176

ABSTRACT

Spontaneous splenic rupture associated with infectious mononucleosis is an infrequent occurrence. Splenectomy has been advocated as the appropriate treatment for these patients. Recently, three patients with spontaneous splenic rupture were successfully treated at our institution without surgery. Management of spontaneous splenic rupture in 37 other patients in the literature was reviewed. Nine of these patients also were treated nonoperatively. Although it has been suggested that splenectomy is the treatment of choice for patients with spontaneous splenic rupture, we believe selective nonoperative treatment of these patients is a realistic and safe option if it is employed appropriately.


Subject(s)
Splenic Rupture/therapy , Adult , Female , Humans , Male , Rupture, Spontaneous
7.
Surgery ; 114(3): 607-12, 1993 Sep.
Article in English | MEDLINE | ID: mdl-8367819

ABSTRACT

Hepatic infarction is an unusual event. A patient is described who had a hepatic infarct after a sigmoid resection. She was found to have occluded superior mesenteric and celiac arteries, with visceral circulation dependent on the inferior mesenteric artery. Disruption of the collateral circulation was presumed to have caused the subsequent liver infarct. A review of the pathophysiology of liver infarction is presented with particular reference to the relation of arterial occlusion to infarction.


Subject(s)
Infarction/etiology , Intestinal Obstruction/surgery , Ischemia/etiology , Liver/blood supply , Mesenteric Arteries , Postoperative Complications , Sigmoid Diseases/surgery , Aged , Aortography , Female , Follow-Up Studies , Humans , Infarction/diagnostic imaging , Infarction/surgery , Ischemia/diagnostic imaging , Ischemia/surgery , Mesenteric Arteries/diagnostic imaging , Tomography, X-Ray Computed
9.
Surgery ; 99(4): 511-3, 1986 Apr.
Article in English | MEDLINE | ID: mdl-3952674

ABSTRACT

A case is presented of postoperative bile peritonitis from an accessory cholecystohepatic bile ductule after cholecystectomy for acute cholecystitis. Accessory bile ductules (ducts of Luschka) are occasionally encountered in the gallbladder fossa but do not drain directly into the gallbladder fundus. Nevertheless, they may be injured during surgery and may go unrecognized. When recognized intraoperatively, ligation is acceptable; however, when they are actively leaking bile and are greater than 2 mm in diameter, repair of injured cholecystohepatic ducts may be indicated. This case serves to reemphasize one argument for the routine placement of drains after cholecystectomy for acute cholecystitis.


Subject(s)
Bile Ducts, Intrahepatic/abnormalities , Cholecystectomy/adverse effects , Chylous Ascites/etiology , Humans , Male , Middle Aged
10.
Surg Gynecol Obstet ; 156(6): 743-8, 1983 Jun.
Article in English | MEDLINE | ID: mdl-6857453

ABSTRACT

Ten patients with diverticulitis of the cecum are reported upon herein. The disease is difficult to distinguish preoperatively from that of appendicitis and may be difficult to distinguish intraoperatively from carcinoma of the cecum. The diverticula are usually solitary and may be of the true or false variety. A review of the literature is presented, and the difficulties of diagnosis and treatment are discussed. We advocate local resection of the diverticulum, when possible, and a right hemicolectomy when the diagnosis is in doubt or when local resection or invagination would jeopardize the ileocecal valve or the blood supply to the intestine. With more awareness of diverticulitis of the cecum, intraoperative diagnosis may be made easier and the treatment simplified.


Subject(s)
Cecal Diseases/diagnosis , Diverticulitis/diagnosis , Adult , Appendicitis/diagnosis , Cecal Diseases/pathology , Cecal Diseases/surgery , Colectomy/methods , Diagnosis, Differential , Diverticulitis/pathology , Diverticulitis/surgery , Female , Humans , Male , Middle Aged
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