Peripheral versus central cannulation for extracorporeal membrane oxygenation: a comparison of limb ischemia and transfusion requirements.

BACKGROUND: Extracorporeal membrane oxygenation (ECMO) can be instituted centrally, through the right atrium and ascending aorta, or peripherally, most commonly using the femoral artery and vein. We sought to investigate the impact of the mode of cannulation on the incidence of limb ischemia, perfusion and overall morbidity. METHODS: A retrospective analysis of 50 consecutive patients over 5 years who underwent ECMO by central or peripheral cannulation was performed. RESULTS: There was no difference in the incidence of limb ischemia and end-organ perfusion when peripheral and central cannulation cohorts were compared. Central cannulation was associated with a higher incidence of bleeding from the cannulation site (64% vs. 18%, P = 0.002), blood product utilization and reoperation (66% vs. 14%, P < 0.0001). 30-day mortality was similar in both cohorts (46% peripheral, 50% central, P = 0.8). CONCLUSION: Our results suggest that there is comparable tissue perfusion and limb ischemia with both cannulation techniques. Central cannulation is associated with a higher incidence of bleeding, higher transfusion rates, a greater need for reoperation and greater resource utilization. Therefore, peripheral cannulation is safe and may be advantageous in certain clinical scenarios.

Surgical treatment of permanent atrial fibrillation using microwave energy ablation: a prospective randomized clinical trial.

OBJECTIVE: Radiofrequency or the use of microwave energy in combination with atrial size reduction during open heart surgery have been reported to be effective in up to 75% in the treatment of permanent atrial fibrillation. However, no data from prospective randomized trials using microwave energy are available. METHODS: Forty-three patients with permanent atrial fibrillation undergoing open-heart surgery were randomly stratified into treatment group receiving microwave ablation and atrial size reduction (n=24) or control group (n=19). Patients in either group were treated with amiodarone or sotalol for 3 months if sinus rhythm or any atrioventricular rhythm was successfully restored. Follow-up time points were at 3, 6 and 12 month after surgery. RESULTS: In the treatment group 22 out of 24 patients (91,7%) were successfully converted to sinus rhythm by using intraoperative microwave ablation therapy whereas only six out of 19 (31.5%) patients converted to sinus rhythm directly after surgery. At 12-month follow-up there were still a significantly higher percentage of patients in the treatment group free from atrial fibrillation when compared to control (80 vs. 33.3%, P=0.036). CONCLUSION: The preliminary data from this first prospectively randomized trial indicate that microwave ablation combined with atrial size reduction is a safe and highly efficient treatment in permanent atrial fibrillation.

[Surgical treatment of aortic valve disease in old age]. / Keine Angst vorm Klappenersatz. Auch bei Senioren ist der Nutzen meist grösser als das Risiko.

In terms of long-term survival and quality of life, excellent results with aortic valve replacement (AVR) can also be achieved in patients older than 70 years of age. An indication for this procedure is given in symptomatic patients with significant aortic valve stenosis, patients with severe acute aortic insufficiency (AI), those with signs of cardiac insufficiency but still normal left ventricular function, and asymptomatic AI patients with an ejection fraction of less than 50% and/or an end-diastolic LV diameter (EDD) of more than 75 mm or an end-systolic diameter (ESD) of more than 55 mm. Many patients with a heart defect in need of surgical treatment also have CAD as well, in which case a bypass should be performed at the same time. For AVR, both mechanical and biological prostheses are available, the latter being regarded as the method of choice in patients aged over 70. The mechanical variant requires life-long anticoagulation therapy with phenprocoumon.

Continuous transesophageal echocardiographic (TEE) monitoring during port-access cardiac surgery.

BACKGROUND: Since the introduction of the closed-chest minimally invasive heart surgery using the Port-Access system a variety of monitoring techniques including fluoroscopy, transesophageal echocardiography (TEE) and invasive pressure measurements have been described. We investigated whether or not single TEE is feasible for perioperative monitoring of the placement, localization and proper function of the endovascular cardiopulmonary bypass (CPB) devices. METHODS: Fifty-one patients (35 mitral valve repair or replacement [MVR], 8 coronary artery bypass grafting [CABG], 5 atrial septal defects [ASD] and 3 left atrial myxoma) were subjected to Port-Access surgery (PAS). Intraoperative Omniplane-TEE (2D- and color-flow Doppler techniques) was used as the leading monitoring device for correct positioning of the endopulmonary vent catheter and the venous cannula, and for the visualization of the guide wire and the endoaortic occlusion catheter (Endoclamp). After balloon inflation, its proper positioning and function during endo-aortic occlusion, sufficient delivery of cardioplegia into the coronary ostia, absence of leakage flow and adequate venting were controlled. Left and right radial artery catheters as well as aortic root pressure measurements served as controls. Additional fluoroscopy was used as standby device. RESULTS: In 46 patients (90.1%) sufficient perioperative monitoring was provided by single TEE. In five cases additional intermittent fluoroscopy was necessary for correct positioning of the guide wire (CABG) and the Endoclamp (three MVR and one ASD). Dislocation of the Endoclamp into the left ventricle was observed once but was successfully corrected by TEE guidance. Weaning from CPB and de-airing were easily guided with TEE. We did not observe balloon-mediated aortic injury or aortic valve dysfunction, and myocardial recovery from CPB was uneventful. All cases of MVRs showed sufficient results (68% without evidence of regurgitation, 32% showed residual mitral valve incompetence of less than grade II). Neither perivalvular leakage (MV-replacement) nor shunt- (residual ASD) flow were detectable. CONCLUSIONS: We recommend single TEE as a safe and effective on-line imaging device for monitoring the endovascular CPB system during PAS. Fluoroscopy with its potential risk for the patients and the staff due to x-ray exposure should only be used in the presence of peripheral vascular disease or when echocardiographic imaging is insufficient.

Clinical relevance of accuracy of pedicle screw placement. A computed tomographic-supported analysis.

STUDY DESIGN: The location of pedicle screws (n = 244) and the increase in the pedicle diameter were determined by computed tomography after screw removal in 50 patients with 360 degrees lumbar fusions. The neurologic findings were examined before and after surgery. OBJECTIVES: To evaluate the correlation between the accuracy of pedicle screw placement and preoperative and postoperative neurologic findings. SUMMARY OF BACKGROUND DATA: Incorrect placement of pedicle screws that was detected by computed tomography has been published in several studies. Simultaneous pathologic neurologic deficits are thought to be created by an eccentric screw track. METHODS: Two observers controlled the screw tracts and pedicle diameters. The results were compared with preoperative and postoperative neurologic findings. RESULTS: Fifty-nine percent (144 of 244) of screws were placed centrally in the pedicle. More than half of the eccentric screws (100, 41%; medial 79, 32.4%; lateral 21, 8.6%) penetrated the pedicle wall less than 2 mm (51; 20.9%). In only one patient (0.5%) a radicular irritation was found without objective electrophysiologic correlation when the screw was more than 6 mm medial to the pedicle wall. After screw removal, an insignificant increase in the size of the pedicle diameter in L1-S1 was noted. CONCLUSIONS: Experienced surgeons implant pedicle screws with an accuracy of approximately 80%. The accuracy could be improved by using image-guided insertion equipment. The neurologic symptoms are rarely influenced by an eccentric pedicle screw tract even if penetration of the pedicle wall is more than 6 mm. The results stress the importance of preoperative planning (pedicle diameter, pedicle angle, screw length) when implanting transpedicular fixators.

Exogenous lumbar spondylodiscitis following a stabwound injury and vertebral fracture. A case report and review of the literature.

Exogenous spondylodiscitis is a rare event and is usually iatrogenic. Non-iatrogenic exogenous spondylodiscitis has been described in the literature following transabdominal gunshot wounds associated with injury to the intestines and spine. Several cases of traumatic meningitis and one of a traumatic meningocele following an injury of the spinal sac have been reported. No report of exogenous spondylodiscitis complicating a stabwound has been published. This is a report of exogenous spondylodiscitis following a paravertebral stabwound with a knife in association with a superior wedge fracture of L2.