Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
Am J Transplant ; 4(8): 1375-8, 2004 Aug.
Article in English | MEDLINE | ID: mdl-15268744

ABSTRACT

We report a case of a 32-year-old female with histologically and clinically inactive chronic hepatic C infection, who received a cadaveric renal transplant from a hepatitis C-positive donor with a different genotype. The genotype mismatch (genotype 1 to genotype 2) and change to tacrolimus-based immunosuppression resulted in severe hepatitis C infection characterized by a 10-fold increase in transaminase levels and grade 3 inflammation histologically. Our report highlights the risk of genotype-mismatch transplants in solid organ transplantation.


Subject(s)
Genotype , Hepacivirus/genetics , Hepatitis C/etiology , Hepatitis C/genetics , Kidney Transplantation/methods , Liver Transplantation/methods , Adult , Biopsy , Female , Graft Rejection , Hepatitis C/therapy , Histocompatibility Testing , Humans , Immunosuppressive Agents/pharmacology , Liver/pathology , Polymerase Chain Reaction , Tacrolimus/pharmacology , Time Factors , Transaminases/metabolism , Transplantation, Homologous/methods , Treatment Outcome
SELECTION OF CITATIONS
SEARCH DETAIL
...