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1.
IEEE Trans Image Process ; 7(1): 13-26, 1998.
Article in English | MEDLINE | ID: mdl-18267376

ABSTRACT

In this paper, we present fast and efficient methods for the lossy encoding of object boundaries that are given as eight-connect chain codes. We approximate the boundary by a polygon, and consider the problem of finding the polygon which leads to the smallest distortion for a given number of bits. We also address the dual problem of finding the polygon which leads to the smallest bit rate for a given distortion. We consider two different classes of distortion measures. The first class is based on the maximum operator and the second class is based on the summation operator. For the first class, we derive a fast and optimal scheme that is based on a shortest path algorithm for a weighted directed acyclic graph. For the second class we propose a solution approach that is based on the Lagrange multiplier method, which uses the above-mentioned shortest path algorithm. Since the Lagrange multiplier method can only find solutions on the convex hull of the operational rate distortion function, we also propose a tree-pruning-based algorithm that can find all the optimal solutions. Finally, we present results of the proposed schemes using objects from the Miss America sequence.

2.
IEEE Trans Image Process ; 7(11): 1505-23, 1998.
Article in English | MEDLINE | ID: mdl-18276217

ABSTRACT

We propose an optimal quadtree (QT)-based motion estimator for video compression. It is optimal in the sense that for a given bit budget for encoding the displacement vector field (DVF) and the QT segmentation, the scheme finds a DVF and a QT segmentation which minimizes the energy of the resulting displaced frame difference (DFD). We find the optimal QT decomposition and the optimal DVF jointly using the Lagrangian multiplier method and a multilevel dynamic program. We introduce a new, very fast convex search for the optimal Lagrangian multiplier lambda(*), which results in a very fast convergence of the Lagrangian multiplier method. The resulting DVF is spatially inhomogeneous, since large blocks are used in areas with simple motion and small blocks in areas with complex motion. We also propose a novel motion-compensated interpolation scheme which uses the same mathematical tools developed for the QT-based motion estimator. One of the advantages of this scheme is the globally optimal control of the tradeoff between the interpolation error energy and the DVF smoothness. Another advantage is that no interpolation of the DVF is required since we directly estimate the DVF and the QT-segmentation for the frame which needs to be interpolated. We present results with the proposed QT-based motion estimator which show that for the same DFD energy the proposed estimator uses about 25% fewer bits than the commonly used block matching algorithm. We also experimentally compare the interpolated frames using the proposed motion compensated interpolation scheme with the reconstructed original frames.

3.
IEEE Trans Image Process ; 6(11): 1487-502, 1997.
Article in English | MEDLINE | ID: mdl-18282908

ABSTRACT

We present a theory for the optimal bit allocation among quadtree (QT) segmentation, displacement vector field (DVF), and displaced frame difference (DFD). The theory is applicable to variable block size motion-compensated video coders (VBSMCVC), where the variable block sizes are encoded using the QT structure, the DVF is encoded by first-order differential pulse code modulation (DPCM), the DFD is encoded by a block-based scheme, and an additive distortion measure is employed. We derive an optimal scanning path for a QT that is based on a Hilbert curve. We consider the case of a lossless VBSMCVC first, for which we develop the optimal bit allocation algorithm using dynamic programming (DP). We then consider a lossy VBSMCVC, for which we use Lagrangian relaxation, and show how an iterative scheme, which employs the DP-based solution, can be used to find the optimal solution. We finally present a VBSMCVC, which is based on the proposed theory, which employs a DCT-based DFD encoding scheme. We compare the proposed coder with H.263. The results show that it outperforms H.263 significantly in the rate distortion sense, as well as in the subjective sense.

4.
Eur J Pharmacol ; 224(1): 97-8, 1992 Nov 24.
Article in English | MEDLINE | ID: mdl-1451747

ABSTRACT

It is shown that D-cycloserine has cognition-enhancing properties in quinolinic acid hippocampal-lesioned rats. Lesioned rats had a severe impairment of working memory in an allocentric spatial reversal paradigm in the 8-arm maze, and performance could be restored with 12 mg/kg i.p. D-cycloserine, given 30 min before testing. The present findings favour the testing of D-cycloserine for clinical efficacy in patients with Alzheimer's disease with loss of pyramidal neurons and disconnected glycine-NMDA receptor activation.


Subject(s)
Cognition Disorders/drug therapy , Cycloserine/pharmacology , Hippocampus/drug effects , Memory Disorders/drug therapy , Analysis of Variance , Animals , Male , Quinolinic Acid/toxicity , Rats , Rats, Sprague-Dawley
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