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2.
Obesity (Silver Spring) ; 23(11): 2133-41, 2015 Nov.
Article in English | MEDLINE | ID: mdl-26530929

ABSTRACT

OBJECTIVE: To determine the effect on weight of two mobile technology-based (mHealth) behavioral weight loss interventions in young adults. METHODS: Randomized, controlled comparative effectiveness trial in 18- to 35-year-olds with BMI ≥ 25 kg/m(2) (overweight/obese), with participants randomized to 24 months of mHealth intervention delivered by interactive smartphone application on a cell phone (CP); personal coaching enhanced by smartphone self-monitoring (PC); or Control. RESULTS: The 365 randomized participants had mean baseline BMI of 35 kg/m(2) . Final weight was measured in 86% of participants. CP was not superior to Control at any measurement point. PC participants lost significantly more weight than Controls at 6 months (net effect -1.92 kg [CI -3.17, -0.67], P = 0.003), but not at 12 and 24 months. CONCLUSIONS: Despite high intervention engagement and study retention, the inclusion of behavioral principles and tools in both interventions, and weight loss in all treatment groups, CP did not lead to weight loss, and PC did not lead to sustained weight loss relative to Control. Although mHealth solutions offer broad dissemination and scalability, the CITY results sound a cautionary note concerning intervention delivery by mobile applications. Effective intervention may require the efficiency of mobile technology, the social support and human interaction of personal coaching, and an adaptive approach to intervention design.


Subject(s)
Behavior Therapy/methods , Cell Phone , Mobile Applications , Overweight/therapy , Telemedicine/methods , Weight Reduction Programs/methods , Adolescent , Adult , Body Weight , Female , Humans , Male , Obesity/psychology , Obesity/therapy , Overweight/psychology , Social Support , Weight Loss , Young Adult
3.
Contemp Clin Trials ; 37(2): 333-41, 2014 Mar.
Article in English | MEDLINE | ID: mdl-24462568

ABSTRACT

BACKGROUND: The obesity epidemic has spread to young adults, leading to significant public health implications later in adulthood. Intervention in early adulthood may be an effective public health strategy for reducing the long-term health impact of the epidemic. Few weight loss trials have been conducted in young adults. It is unclear what weight loss strategies are beneficial in this population. PURPOSE: To describe the design and rationale of the NHLBI-sponsored Cell Phone Intervention for You (CITY) study, which is a single center, randomized three-arm trial that compares the impact on weight loss of 1) a behavioral intervention that is delivered almost entirely via cell phone technology (Cell Phone group); and 2) a behavioral intervention delivered mainly through monthly personal coaching calls enhanced by self-monitoring via cell phone (Personal Coaching group), each compared to 3) a usual care, advice-only control condition. METHODS: A total of 365 community-dwelling overweight/obese adults aged 18-35 years were randomized to receive one of these three interventions for 24 months in parallel group design. Study personnel assessing outcomes were blinded to group assignment. The primary outcome is weight change at 24 [corrected] months. We hypothesize that each active intervention will cause more weight loss than the usual care condition. Study completion is anticipated in 2014. CONCLUSIONS: If effective, implementation of the CITY interventions could mitigate the alarming rates of obesity in young adults through promotion of weight loss. ClinicalTrial.gov: NCT01092364.


Subject(s)
Behavior Therapy/methods , Cell Phone , Overweight/therapy , Weight Loss , Adolescent , Adult , Behavior Therapy/instrumentation , Body Weights and Measures , Humans , Obesity/therapy , Self Report , Socioeconomic Factors , Young Adult
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