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1.
JAMA Otolaryngol Head Neck Surg ; 149(8): 754-755, 2023 08 01.
Article in English | MEDLINE | ID: mdl-37382925

ABSTRACT

A 15-year-old male presented with dysphagia to solid foods, and dyspnea when laying on the right side that had progressed during 8 months. What is your diagnosis?


Subject(s)
Deglutition Disorders , Humans , Adolescent , Deglutition Disorders/diagnosis , Deglutition Disorders/etiology , Dyspnea/diagnosis , Dyspnea/etiology , Diagnosis, Differential
2.
Head Neck ; 45(7): E31-E35, 2023 07.
Article in English | MEDLINE | ID: mdl-37141398

ABSTRACT

INTRODUCTION: Metastatic renal cell carcinoma (RCC) represents 25%-42% of metastatic thyroid malignancies. Propensity for RCC to demonstrate intravascular extension to the inferior vena cava is well documented. We present an analogous phenomenon of intravascular extension to the internal jugular vein (IJV) from thyroid gland metastasis. METHODS: A 69-year-old male presented with metastatic RCC of the right thyroid lobe. Imaging demonstrated tumor thrombosis of the ipsilateral IJV, extending inferiorly to the junction of the brachiocephalic, subclavian, and internal jugular veins within the mediastinum. RESULTS: Surgical excision required control of both the IJV in the neck and mediastinal venous great vessels via sternotomy, prior to subtotal thyroidectomy and venotomy for en bloc resection. CONCLUSION: This case report describes metastatic RCC to the thyroid gland with cervicothoracic venous tumor thrombosis successfully treated with subtotal thyroidectomy, sternotomy for venotomy and tumor thrombectomy, and preservation of IJV conduit.


Subject(s)
Carcinoma, Renal Cell , Kidney Neoplasms , Thrombosis , Thyroid Neoplasms , Venous Thrombosis , Male , Humans , Aged , Carcinoma, Renal Cell/surgery , Carcinoma, Renal Cell/pathology , Kidney Neoplasms/surgery , Kidney Neoplasms/pathology , Venous Thrombosis/diagnostic imaging , Venous Thrombosis/etiology , Venous Thrombosis/surgery , Thyroid Neoplasms/pathology
3.
Int J Pediatr Otorhinolaryngol ; 167: 111336, 2023 Apr.
Article in English | MEDLINE | ID: mdl-36868145

ABSTRACT

OBJECTIVES: Determine if systemic corticosteroids administration is associated with reduced length of stay, surgical intervention, and abscess formation in pediatric patients with orbital complications of rhinosinusitis. METHODS: Systematic review and meta-analysis were performed utilizing the PubMed and MEDLINE databases to identify articles published between January 1990 and April 2020. Retrospective cohort study of the same patient population over the same time period at our institution. RESULTS: Eight studies, 477 individuals, met criteria for inclusion in the systematic review. 144 patients (30.2%) received systemic corticosteroids, while 333 patients (69.8%) did not. Meta-analyses of frequency of surgical intervention and subperiosteal abscess showed no difference between those who did and did not receive systemic steroids ([OR = 1.06; 95% CI: 0.46 to 2.48] and [OR = 1.08; 95% CI: 0.43 to 2.76], respectively). 6 articles evaluated hospital length of stay (LOS). 3 of these reported enough data to perform meta-analysis, which showed patients with orbital complications who received systemic corticosteroids had shorter mean hospital LOS when compared with those who did not receive systemic steroids (SMD = -2.92, 95% CI: 5.65 to -0.19). CONCLUSION: While available literature was limited, systematic review and meta-analysis suggests systemic corticosteroids decrease length of stay for hospitalized pediatric patients with orbital complications of sinusitis. Further research is needed to more clearly define the role of systemic corticosteroids as an adjunctive treatment.


Subject(s)
Abscess , Sinusitis , Child , Humans , Abscess/drug therapy , Abscess/etiology , Retrospective Studies , Adrenal Cortex Hormones/therapeutic use , Steroids , Sinusitis/complications , Sinusitis/drug therapy
4.
Ann Otol Rhinol Laryngol ; 132(4): 431-439, 2023 Apr.
Article in English | MEDLINE | ID: mdl-35656804

ABSTRACT

OBJECTIVES: Retrospectively analyze head and neck Langerhans Cell Histiocytosis at a rural tertiary referral center and compare results with previously published data. METHODS: Electronic health record review was performed from 2003 to 2019. Patients with biopsy proven LCH with primary head and neck involvement were included. Demographics, presentation, imaging characteristics, treatment modality, delay in diagnosis (DD, ≥60 days), and outcomes were analyzed and reported. RESULTS: Twenty-four patients were included. The most common presenting symptoms were otorrhea (n = 6) and scalp pain or swelling (n = 6). All patients had bony involvement. The most common site was facial or skull lesions (n = 20). Most skull lesions (75%) demonstrated CNS risk. Six patients were treated with primary surgery, 15 with primary chemotherapy, and 3 with surgery plus adjuvant chemotherapy. Nine patients experienced relapse of disease with median time to documented relapse of 11.4 months; all were treated with salvage chemotherapy to achieve complete remission (median follow-up: 72 months). Patients most likely to relapse were those with multisystem disease (5/7, 71.4%), temporal bone lesions (4/7, 57.1%), and DD (7/12, 58.3%). Of the 9 total patients who experienced relapse, 78% had a delay in diagnosis. CONCLUSIONS: LCH is a complex disease process in which diagnosis can be delayed if not considered in the differential. Within the head and neck, the skull, including isolated temporal bone involvement, is the most common site of involvement. Treatment modality does not appear to have an influence on relapse rates. Relapse was more likely to occur in the first year after treatment and close monitoring is required.


Subject(s)
Head , Histiocytosis, Langerhans-Cell , Humans , Retrospective Studies , Tertiary Care Centers , Head/pathology , Histiocytosis, Langerhans-Cell/diagnosis , Recurrence
5.
Ann Otol Rhinol Laryngol ; 130(10): 1125-1131, 2021 Oct.
Article in English | MEDLINE | ID: mdl-33629604

ABSTRACT

OBJECTIVES: This is a qualitative study to explore the utility of gray-scale inversion or the "invert" function of high-resolution computed tomography (HRCT) scans in the diagnosis of temporal bone anatomy and pathology. METHODS: This is a case series describing an innovative application of an existing image processing tool to visualize temporal bone anatomy and pathology. Illustrative patients at a tertiary referral center with otologic symptoms and findings leading to HRCT scans of the temporal bone were included. Diagnostic HRCT scans were evaluated utilizing the gray-scale inversion function (invert function). RESULTS: Nine illustrative cases which demonstrate conditions such as persistent stapedial artery, membranous stapes footplate, total ossicular prosthesis migration into the vestibule, third window syndrome such as superior semicircular canal dehiscence (SSCD) and cochlea-facial nerve dehiscence, otosclerosis, and ossicular chain discontinuity are included. The enhanced visualization was confirmed surgically in 3 cases, and 1 had physiological confirmation using cervical vestibular evoked myogenic potentials (cVEMP). CONCLUSIONS: Gray-scale inversion can be used to improve visualization of temporal bone anatomy and pathologic changes when diagnoses are in doubt. The invert function is a useful adjunct in the armamentarium of both radiologists and otologists when evaluating HRCT of the temporal bone.


Subject(s)
Labyrinth Diseases/diagnosis , Otosclerosis/diagnosis , Temporal Bone/diagnostic imaging , Tomography, X-Ray Computed/methods , Vestibule, Labyrinth/diagnostic imaging , Adult , Aged , Aged, 80 and over , Cochlea/diagnostic imaging , Female , Humans , Male , Middle Aged
6.
Int J Pediatr Otorhinolaryngol ; 112: 80-81, 2018 Sep.
Article in English | MEDLINE | ID: mdl-30055745

ABSTRACT

The disease of parapharyngeal abscess is well known to the otolaryngologist and is commonly managed via transoral, transcervical, or combined incision and drainage. We report a novel approach to an abscess that was drained through the external auditory canal (EAC). An otherwise healthy 2-year-old female presented with a 4-day history of fevers, decreased oral intake, neck stiffness, and voice changes. CT neck with contrast revealed a deep abscess in the left neck extending from the peritonsillar space into the parapharyngeal space in close proximity to the anterior aspect of the EAC. Because the EAC was the closest surface to the abscess collection, we elected to attempt drainage through this route. Successful incision and drainage was performed via transcanal approach. She received intravenous antibiotics and steroids post-operatively and surgical packing was removed. She was discharged home on post-operative day 5 afebrile and tolerating a regular diet and continued to do well at most recent outpatient follow-up.


Subject(s)
Abscess/surgery , Drainage/methods , Ear Canal/surgery , Pharyngeal Diseases/surgery , Abscess/diagnostic imaging , Abscess/drug therapy , Adrenal Cortex Hormones/therapeutic use , Anti-Bacterial Agents/therapeutic use , Child, Preschool , Female , Fever , Humans , Pharyngeal Diseases/diagnostic imaging , Pharyngeal Diseases/drug therapy , Tomography, X-Ray Computed
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