A general chemotherapy myelotoxicity score to predict febrile neutropenia in hematological malignancies.

BACKGROUND: Chemotherapy-induced neutropenia is the most common adverse effect of chemotherapy and is often complicated by febrile neutropenia (FN). The objective of this study is to validate a classification of aggressiveness of a chemotherapy regimen and to evaluate its usefulness in a risk prediction model of FN in patients with hematological cancer at the beginning of a chemotherapy cycle. PATIENTS AND METHODS: Two hundred and sixty-six patients were prospectively enrolled and followed during 1053 cycles. Relevant patient informations were collected at the beginning of the first cycle and the number of days of FN were counted in the follow-up [dichotomized (no FN versus >or= 1 day of FN)]. RESULTS: Aggressive chemotherapy regimen is the major predictor of FN [odds ratio 5.2 (3.2-8.4)]. The other independent predictors are the underlying disease, an involvement of bone marrow, body surface

Interactions between benthic macroinvertebrates and fishes in a low order stream in Campos de Cima da Serra, RS, Brazil / Interações entre macroinvertebrados bentônicos e peixes em um rio de baixa ordem nos Campos de Cima da Serra, RS, Brasil

Benthic macroinvertebrates constitute the link between organic matter input in streams and fishes. However, the possibility of influence of predators on the invertebrates is still a controversial issue. The possibility of alteration of the benthic community by the modification in predation in a stream in the South of Brazil was studied by means of an exclusion experiment under semi-natural conditions. The exclusion showed an increase in the abundance of Plecoptera in the river where the rainbow trout was introduced, the larvae of Trichoptera also increased in abundance in the units of fish exclusion. This difference does not confirm the pressure applied by the trout on the benthic macro fauna due to differences in ichthyofauna and in the habitat of both rivers. Nevertheless, it points to the need for the development of studies concerning the trophic relations and the possible effects of this introduction in the aquatic biota.

Os macroinvertebrados bentônicos exercem a ligação entre a entrada de matéria orgânica nos rios e os peixes. Porém, a possibilidade de influência dos predadores sobre os invertebrados é uma questão ainda controversa. A possibilidade de alteração da comunidade bentônica, pela modificação na predação em um rio no sul do Brasil, foi estudada através de um experimento de exclusão em condições seminaturais. A exclusão resultou no aumento na abundância de Plecoptera no rio onde é feita a introdução de truta arco-íris; as larvas de Trichoptera também aumentaram em abundância nas unidades onde se efetuou a exclusão. Essa diferença não pode ser atribuída à presença das trutas, devido às diferenças na ictiofauna e de habitat dos dois rios. Entretanto mostra a necessidade de desenvolvimento de estudos acerca das relações tróficas e possíveis efeitos desta introdução sobre a biota aquática

Interactions between benthic macroinvertebrates and fishes in a low order stream in Campos de Cima da Serra, RS, Brazil.

Benthic macroinvertebrates constitute the link between organic matter input in streams and fishes. However, the possibility of influence of predators on the invertebrates is still a controversial issue. The possibility of alteration of the benthic community by the modification in predation in a stream in the South of Brazil was studied by means of an exclusion experiment under semi-natural conditions. The exclusion showed an increase in the abundance of Plecoptera in the river where the rainbow trout was introduced, the larvae of Trichoptera also increased in abundance in the units of fish exclusion. This difference does not confirm the pressure applied by the trout on the benthic macro fauna due to differences in ichthyofauna and in the habitat of both rivers. Nevertheless, it points to the need for the development of studies concerning the trophic relations and the possible effects of this introduction in the aquatic biota.

The influence of reperitonization on the induction of formation of intraperitoneal adhesions by a polypropylene mesh prosthesis. An experimental study in rats.

The correction of groin hernias has increasingly been performed by transperitoneal videolaparoscopic methods, using a polypropylene mesh. This could lead to an increased incidence of adhesion formation. The incidence of adhesions induced by mesh placement and the influence of reperitonization was observed on 40 male adult Wistar rats. Adhesions were significantly more common on the groups in which the prosthesis was placed (59% vs 95%; p = 0.01), as well as on the groups in which reperitonization was performed (58% vs 100%; p = 0.03). The results suggest that polypropylene mesh placement and reperitonization are each independent factors in the induction of adhesions formation.