ABSTRACT
In a prospective investigation, a rapid latex test for Helicobacter pylori in the serum (Pyloriset) was carried out in 39 patients with recurrent abdominal pain aged from six to 15 years. The test was positive in 19 patients. All of these children were subjected to gastroduodenoscopy. Seven cases showed a Helicobacter-associated chronic active antrum gastritis, whereas in the remaining 12 children gastritis not induced by Helicobacter or normal mucosa was found. Of the 20 Pyloriset-negative patients, only five could be biopsied. One of these showed a Helicobacter pylori-induced antrum gastritis. The latex test investigated had a positive predictive value which was too low (37%) to make it helpful in deciding for or against gastroduodenoscopy and the general anesthesia mostly associated with this.
Subject(s)
Abdominal Pain/etiology , Gastritis/diagnosis , Helicobacter Infections/diagnosis , Helicobacter pylori , Latex Fixation Tests , Abdominal Pain/microbiology , Adolescent , Child , Chronic Disease , Diagnosis, Differential , Endoscopy, Digestive System , Female , Gastritis/complications , Gastritis/microbiology , Helicobacter Infections/complications , Helicobacter Infections/microbiology , Humans , Male , Predictive Value of TestsABSTRACT
Two cases of aggressive fibromatosis of the thyroid gland region were studied by histological, immunhistological and electron-microscopic methods. Contractile cells can be found in all tissue preparations using human serum containing antibodies to smooth muscle, especially in the periphery of the tumor. These cells have the characteristics of myofibroblasts by electron microscopy. The central areas of the tumor are composed of hyalin thickened bundles of collagen fibres with few cellular elements. The myofibroblast is thus considered to be the characteristic cell type of the tumor, and the pathogenesis and histogenesis of the lesion are discussed.
Subject(s)
Fibroma/ultrastructure , Head and Neck Neoplasms/ultrastructure , Adult , Aged , Collagen , Connective Tissue/ultrastructure , Female , Fibroblasts/ultrastructure , Humans , Immunoenzyme Techniques , Microscopy, Electron , Muscle, SmoothABSTRACT
A case of irreversible panmyelophthisis with fatal outcome in a 28-year-old patient is reported, following 8-year continuous abuse of anorectic drugs.
