ABSTRACT
A patient is described with a hormone-secreting interstitial cell tumor, manifesting metastasis 7 years after removal of a reportedly benign primary tumor. The late course of the disease was followed by computerized tomography and serum hormone assays. Previously reported cases of metastatic interstitial cell tumor are reviewed, and prognostic features and treatment are discussed.
Subject(s)
Hormones, Ectopic/metabolism , Leydig Cell Tumor/secondary , Retroperitoneal Neoplasms/secondary , Testicular Neoplasms/metabolism , Aldosterone/metabolism , Estradiol/metabolism , Humans , Hydrocortisone/metabolism , Leydig Cell Tumor/metabolism , Male , Middle Aged , Testosterone/metabolism , Time FactorsABSTRACT
A limited course of intravesical mitomycin C was tested in 12 patients who had at least three, and an average of six, occurrences of superficial bladder cancer, and were at high risk for subsequent recurrences. After intravesical chemotherapy, recurrence rates were significantly less than rates prior to chemotherapy.
Subject(s)
Mitomycins/therapeutic use , Neoplasm Recurrence, Local/drug therapy , Urinary Bladder Neoplasms/drug therapy , Administration, Intravesical , Aged , Humans , Middle Aged , Mitomycin , Mitomycins/administration & dosageABSTRACT
A rare, if not unique, case of sigmoid colon perforation by a balloon, self-inserted transanally, is described. Mechanical properties of the sigmoid colon make it prone to rupture by pneumatic distention. Management depends on amount of peritoneal contamination, timing, and associated injury. With prompt surgery, isolated traumatic sigmoid colon perforations have a good prognosis.