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Z Gerontol Geriatr ; 44(4): 268-9, 2011 Aug.
Article in English | MEDLINE | ID: mdl-21732154

ABSTRACT

An 85-year-old man with myasthenia gravis was successfully treated with methotrexate (10 mg/week), pyridostigmine and prednisolone (0-30 mg/day) for over 10 years. Then, he developed dysphagia and lost weight. Gastroscopy revealed Candida esophagitis. The patient received nystatin for 2 weeks. Methotrexate was stopped, and immunosuppressive therapy was continued with prednisolone alone. The patient has now remained in good condition for over 1 year. Although dysphagia is a typical symptom of myasthenia gravis, swallowing disturbances should not be attributed hastily to this disease, since they may also be a complication of therapy.


Subject(s)
Candidiasis/complications , Candidiasis/diagnosis , Deglutition Disorders/diagnosis , Deglutition Disorders/etiology , Esophagitis/complications , Esophagitis/diagnosis , Myasthenia Gravis/diagnosis , Aged , Antifungal Agents/therapeutic use , Candidiasis/drug therapy , Diagnosis, Differential , Drug Therapy, Combination , Esophagitis/drug therapy , Gastroscopy , Humans , Immunosuppressive Agents/therapeutic use , Male , Methotrexate/therapeutic use , Myasthenia Gravis/drug therapy , Nystatin/therapeutic use , Prednisolone/therapeutic use , Pyridostigmine Bromide/therapeutic use
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