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1.
Pediatr Med Chir ; 19(2): 137-9, 1997.
Article in Italian | MEDLINE | ID: mdl-9312751

ABSTRACT

The Authors describe a case of renal agenesis with ipsilateral ovarian dysplasia. The clinical features are abdominal mass and pain and then the treatment is laparoscopic ablation.


Subject(s)
Abnormalities, Multiple , Kidney/abnormalities , Ovary/abnormalities , Abdomen/diagnostic imaging , Adolescent , Female , Humans , Kidney/diagnostic imaging , Ovary/diagnostic imaging , Ovary/surgery , Radiography , Ultrasonography
2.
Radiol Med ; 85(4): 416-20, 1993 Apr.
Article in Italian | MEDLINE | ID: mdl-8516469

ABSTRACT

A positive correlation between the attenuation values of blood in vitro and hemoglobin concentration has been described by other authors. Our study is aimed at: 1) investigating the influence of artifacts on the measurement of blood density in vivo, 2) verifying the possible correlation between blood values and Hounsfield's units (HU) in vivo, 3) assessing whether such a correlation may be useful in calculating hemoglobin concentration, 4) investigating whether a significant difference in blood density exists between normal and anemic subjects, and 5) investigating the eventual borderline density values which separate the two populations. Fifty adult patients underwent CT of the upper abdomen for several clinical reasons. Twenty-six males, mean age 63 +/- 15 SD, and 24 females, mean age 63 +/- 14 SD, were included in our series. The two groups were then subdivided into two additional groups including anemic and normal subjects -14 g/dl and 12 g/dl being taken as the borderline values for males and females, respectively. Blood density was measured after defining two regions of interest (ROI) on the aorta and inferior vena cava. The results show that: 1) there are few image artifacts, which are sometimes detected only because of different numbers in aorta and vena cava; for quantitative blood measurement, 4 HU was considered as an acceptable difference; 2) the correlation between HU and hemoglobin concentration which was found in vitro was also seen in vivo (r = 0.76, p < 0.001). Furthermore, high positive correlation was observed between attenuation values and red cell count (r = 0.68) or hematocrit (r = 0.75). 3) However, this correlation cannot be used to calculate the patients's blood count since HU dispersion relative to the regression line is too high. The straight line of regressed computation, reporting the density values on the abscissa axis, shows a b = 0.33 slope and the intersection point is a = -1.43, SE b = 0.04, SE a = 1.76 and SE estimate = 1.56. When the mean density value was 43 HU in our sample, the expected hemoglobin value was 12.76 g/dl (+/- 1.58 SD). 4) Nonetheless, a significant difference in blood attenuation values was seen between normal subjects and anemic patients (p < 0.001). 5) This difference identifies a borderline density value, below which the patient is sure to be anemic (99% confidence), but nothing else can be said on the patient's normality: the value is 33 HU for females and 36 HU for males. These values allowed 20% of anemic subjects to be correctly identified, versus 5% of the same group detected with diagnosis images.


Subject(s)
Hematology/methods , Tomography, X-Ray Computed , Aged , Analysis of Variance , Anemia/blood , Artifacts , Blood Viscosity , Female , Hemoglobins/analysis , Humans , Male , Middle Aged , Regression Analysis
3.
Biochim Biophys Acta ; 1037(3): 265-73, 1990 Mar 01.
Article in English | MEDLINE | ID: mdl-2138033

ABSTRACT

The spleen from a patient with hairy-cell leukaemia had beta-N-acetylhexosaminidase activity that could be resolved into three isoenzymes by chromatography on phenyl boronate agarose. Two of these were the major forms, A and B, found in normal tissues but, in addition, there was an 'extra' form that accounted for 15% of total activity. The 'extra' form hydrolysed the synthetic substrate 4-methylumbelliferyl-beta-N-acetylglucosamine 6-sulphate, indicating the presence of alpha-subunits. It was more acidic than A, was less heat-stable and showed no generation of B on denaturation under a variety of conditions. These findings and the immunoblot (Western blotting) analysis demonstrate that the 'extra' form is entirely composed of alpha-subunits, and most closely resembles S, the residual activity in Sandhoff's disease.


Subject(s)
Isoenzymes/isolation & purification , Leukemia, Hairy Cell/enzymology , Spleen/enzymology , beta-N-Acetylhexosaminidases/isolation & purification , Blotting, Western , Chromatography , Drug Stability , Hot Temperature , Humans , Hydrogen-Ion Concentration , Isoelectric Focusing , Isoenzymes/antagonists & inhibitors , Isoenzymes/metabolism , Kinetics , beta-N-Acetylhexosaminidases/antagonists & inhibitors , beta-N-Acetylhexosaminidases/metabolism
4.
Neurology ; 36(2): 267-70, 1986 Feb.
Article in English | MEDLINE | ID: mdl-3945397

ABSTRACT

After years of episodic monocular visual loss, two migraineurs suffered sudden, persisting loss of vision from retinal vascular occlusion. One was a 34-year-old woman with systemic lupus erythematosus who showed abnormalities of the cilioretinal arterial and retinal venous circulations. The other was a 62-year-old man with hypertension and arteriosclerosis who had a central retinal vein occlusion. Persisting monocular visual loss is a rare consequence of migraine. Our cases suggest a role for venous lesions. Occlusion of retinal vessels in some migraineurs may result from the synergistic effect of another vascular disorder with the migraine.


Subject(s)
Migraine Disorders/complications , Retinal Diseases/etiology , Adolescent , Adult , Aged , Arterial Occlusive Diseases/etiology , Female , Humans , Male , Middle Aged , Retina/blood supply
5.
Ann Ophthalmol ; 17(5): 299-302, 1985 May.
Article in English | MEDLINE | ID: mdl-4004011

ABSTRACT

Bilateral uveitic glaucoma occurred in a patient with giant-cell arteritis. The mechanism appeared to be immunologic, not ischemic.


Subject(s)
Giant Cell Arteritis/complications , Glaucoma/complications , Uveitis/complications , Aged , Female , Humans , Iritis/complications
6.
Am J Ophthalmol ; 99(5): 567-70, 1985 May 15.
Article in English | MEDLINE | ID: mdl-2408476

ABSTRACT

Carotid artery obstructive disease, although infrequently diagnosed as a primary or contributing cause of neovascular glaucoma, can produce distinctive characteristics. Decreased perfusion of the ciliary body may decrease aqueous humor production. As a result, such eyes with neovascular glaucoma may occasionally be normotensive or even hypotensive. Fluorescein angiography may show an increased arm-to-retina time and leakage from the major retinal arterioles. Panretinal photocoagulation may not eliminate the anterior segment neovascularization because of anterior segment ischemia. Endarterectomy can significantly increase intraocular pressure as perfusion to the ciliary body returns to normal. These characteristics were found in two patients, a 67-year-old woman and a 49-year-old man, with diabetes and hypertension. In both cases cyclocryotherapy significantly reduced the intraocular pressure and the rubeosis iridis regressed.


Subject(s)
Arterial Occlusive Diseases/complications , Carotid Artery Diseases/complications , Glaucoma/etiology , Aged , Arterial Occlusive Diseases/diagnosis , Carotid Artery Diseases/diagnosis , Female , Glaucoma/diagnosis , Humans , Male , Middle Aged , Neovascularization, Pathologic/diagnosis , Neovascularization, Pathologic/etiology
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