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Kardiol Pol ; 66(6): 669-76; discussion 677, 2008 Jun.
Article in Polish | MEDLINE | ID: mdl-18626837

ABSTRACT

Two cases of large, free-floating right heart thrombi in patients with massive pulmonary embolism and a history of deep vein thrombosis are presented. In a 30-year-old male with prominent obesity and a history of hypertension, disappearance of the thrombus at the end of alteplase infusion coexisted with onset of haemodynamic stabilization. In a 70-year-old female, the thrombus, which persisted despite streptokinase administration, translocated suddenly (during echocardiography) to the pulmonary artery, which resulted in a deterioration in her status. After alteplase administration following heparin infusion, steady clinical and echocardiographic improvement was observed.


Subject(s)
Heart Diseases/drug therapy , Pulmonary Embolism/drug therapy , Thromboembolism/drug therapy , Thrombolytic Therapy/methods , Aged , Echocardiography , Female , Heart Diseases/diagnostic imaging , Humans , Male , Pulmonary Embolism/complications , Pulmonary Embolism/diagnosis , Thromboembolism/diagnosis , Thromboembolism/diagnostic imaging , Tissue Plasminogen Activator/therapeutic use , Treatment Outcome , Urokinase-Type Plasminogen Activator/therapeutic use
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